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BACKGROUND: Androgen insensitivity is caused by mutations in the androgen receptor gene, and is a common etiological factor to ambiguous genitalia in the newborn. This article discusses the role of androgens in sex differentiation, the structure and function of the androgen receptor, the genetic background to androgen insensitivity as well as clinical aspects. MATERIAL AND METHODS: The article is

Use of the harmonic scalpel versus conventional haemostatic techniques in patients with Grave disease undergoing total thyroidectomy: a prospective randomised controlled trial.

INTRODUCTION: Thyrotoxicosis is often considered to be the most difficult thyroid operation because of the high vascularisation and the risk of bleeding. The conventional haemostatic technique in thyroidectomy today include knot tying and electrocoagulation. The introduction of the harmonic scalpel (HS) has led to further research if the use of the HS has any benefits in thyroid surgery. To our kn

Factors influencing subjective perceptions of everyday occupations: Comparing day centre attendees with non-attendees.

Abstract Background: Subjective perceptions of everyday occupations are important for the well-being of people with psychiatric disabilities (PD) and are likely to vary with factors such as attending a day centre or not, activity level, self-mastery, sociodemographic and clinical factors. Aim: To explore differences in subjective perceptions of occupation and activity level between day centre atte

Vuv Laser Spectroscopy

Recently, new optical non-linear materials and frequency-mixing schemes have been developed. This has moved the frontiers of short-wavelength laser spectroscopy into the VUV spectral region. Spectroscopic methods suitable for short-wavelength laser sources are presented.

Reproductive history, lifestyle factors and season as determinants for serum calcium concentrations in women.

Objective. Serum calcium concentrations have been associated with the risk of malignant disease, especially breast cancer. Thus, determinants of serum calcium concentrations, with special regard to risk factors of breast cancer, are of great interest. Material and methods. Previous studies have either been small or they have not focused on reproductive factors. The present study examined serum cal

PCA3 as a diagnostic marker for prostate cancer: A validation study on a Swedish patient population.

Abstract Objective. Prostate cancer antigen 3 in urine (uPCA3) has been shown to perform better than total prostate-specific antigen in serum (tPSA) to predict prostate cancer (PCa) detection. The aim of this study was to validate the diagnostic precision of uPCA3 in a mixed set of patients with no previous history of PCa, including patients with previous negative biopsies. Material and methods. T

Placed in homecare: Living an everyday life restricted by dependence and monitoring

Through a sociological case study this article analyses how, seen from a relational perspective, everyday life for elderly people receiving care in their own homes is lived with dependence on health-care professionals. The healthcare professionals’ time and tasks are assigned and allocated in advance so that the elderly people are neither allowed nor able to vary their response in relation to the

Clinical severity of Mycoplasma pneumoniae (MP) infection is associated with bacterial load in oropharyngeal secretions but not with MP genotype.

BACKGROUND: Disease severity in Mycoplasma pneumoniae (MP) infection could potentially be related to bacterial factors such as MP genotype (MP1 or MP2; distinguished by different adhesions proteins) or bacterial load in airway secretions. We have compared these parameters in patients who were hospitalized for MP pneumonia, with outpatients with mild MP disease. METHODS: MP bacterial load was measu

Low Power Decoding Circuits for Ultra Portable Devices

A wide spread of existing and emerging battery driven wireless devices do not necessarily demand high data rates. Rather, ultra low power, portability and low cost are the most desired characteristics. Examples of such applications are wireless sensor networks (WSN), body area networks (BAN), and a variety of medical implants and health-care aids. Being small, cheap and low power for the individua

Studying the impact of uncertainty in operational release planning - An integrated method and its initial evaluation

Context: Uncertainty is an unavoidable issue in software engineering and an important area of investigation. This paper studies the impact of uncertainty on total duration (i.e., make-span) for implementing all features in operational release planning. Objective: The uncertainty factors under investigation are: (1) the number of new features arriving during release construction, (2) the estimated

Changing biochemical presentation of primary hyperparathyroidism.

PURPOSE: Patients with primary hyperparathyroidism, pHPT, present with milder symptoms than previously. Some, but not all studies, suggest that this change in clinical pattern also implies lower preoperative parathyroid hormone (PTH) and/or calcium levels and smaller adenomas. This is important since reports indicate that smaller adenomas are more difficult to detect on preoperative imaging, possi

On-off Control of an Active Load for Power System Damping-Theory and Field Test

Controlled resistive loads can contribute to damping of electro-mechanical oscillations. This paper presents an on-off damping controller for a single machine system. It was used at a field test in southern Sweden to damp oscillations of a 0.9 MW hydro power generator. The controller used estimated machine frequency as input and controlled a 20 kW resistive load via thyristor switches. The field m