Although sex and gender are recognized as major determinants of health and immunity, their role is rarely considered in clinical practice and public health. We identified six bottlenecks preventing the inclusion of sex and gender considerations from basic science to clinical practice, precision medicine and public health policies. (i) A terminology-related bottleneck, linked to the definitions of

Epileptogenesis is a complex process involving a multitude of changes at the molecular, cellular and network level. Previous studies have identified several key alterations contributing to epileptogenesis and the development of hyper-excitability in different animal models, but only a few have focused on the early stages of this process. For post status epilepticus (SE) temporal lobe epilepsy in p

In recent years, the term circular economy has become central in both research and politics. Inmost writings and policy documents, a circular economy is assumed to presuppose a break fromprevious habits and practices. Cultural and historical perspectives are often neglected, eventhough most preindustrial agriculture and food systems developed methods for the circulationand recycling of resources.

I naturen fångas solljus in via ljus-absorberande molekyler. På liknande sätt kan färgämnen användas för solcells- och artificiell fotosyntes-applikationer för att absorbera solljus, och överföra den exciterade elektronen.Framgångsrika färgämnen har tidigare varit baserade på Ru-polipyridyl-komplex, trots att Ru är ett av de mest ovanliga ämnena i jordskorpan. Detta arbete har som mål att ersätta Nature captures sunlight via light-absorbing molecules.Similarly, photosensitisers are used in applications of solar cells and artificial photosynthesis to absorb sunlight, and transfer the excited electron.Successful photosensitisers have in the past been based on a Ru polipyridyl scaffold, despite Ru being one of the scarcest elements in Earth's crust.This thesis work aims to replace Ru polipyri

Economic history became a discipline with its own chair professors at the Swedish universities at the end of the 1940s. The well-known economic historian Eli Heckscher played a central role for the establishment and his work led to a stronger position for economic history in Sweden than in most other countries. However, his influence was not strong in the formation of the discipline. He always emp

Besides friction and wear, airborne particle emission has become a central parameter when evaluating disc brake performance due to its potential adverse health effects as component of ambient air pollution. The pad friction material of brake system is composed of a mixture of ingredients grouped into four material categories: abrasives, reinforcing fibres, lubricants, and fillers. Some other ingre

The current war in Ukraine has severely disrupted global food supply chains due to the significant decline in the production of grain commodities, of which Ukraine and Russia are major global suppliers. This creates problems in today’s globalised food systems. In particular, a number of countries are heavily dependent on food imports from Ukraine and/or Russia, particularly some developing nations

Hydropower is a clean and efficient technology for producing renewable energy. Assessment and forecasting of hydropower production are important for strategic decision-making. This study aimed to use machine learning models, including adaptive neuro-fuzzy inference system (ANFIS), gene expression programming, random forest (RF), and least square support vector regression (LSSVR), for predicting hy

Why is theorizing important? What does it do? This note reflects on the broad question of what we do when we theorize, taking its starting point from the Greek notion of theoria. The argument is that theorizing as an uncertain journey, i.e. as a form of travelling along a path towards the unknown or unfamiliar, has unjustly fallen into disrepute. The notion of ‘theory’ is today primarily associate

När regeringen, pressad av SD, inte följer ingångna avtal bryter den med svensk tradition. Historiskt har trepartsmodellen haft framgång i att lösa viktiga samhällsproblem. Med staten som opålitlig part riskeras något av det mest svenska vi har, skriver German Bender på den fackföreningsnära tankesmedjan Arena Idé och professor Anders Kjellberg.

In the Asia-Pacific region (APR), extreme precipitation is one of the most critical climate stressors, affecting 60% of the population and adding pressure to governance, economic, environmental, and public health challenges. In this study, we analyzed extreme precipitation spatiotemporal trends in APR using 11 different indices and revealed the dominant factors governing precipitation amount by at

A growing community is constructing a next-generation file format (NGFF) for bioimaging to overcome problems of scalability and heterogeneity. Organized by the Open Microscopy Environment (OME), individuals and institutes across diverse modalities facing these problems have designed a format specification process (OME-NGFF) to address these needs. This paper brings together a wide range of those c