Group 2 innate lymphoid cells (ILC2) are a subset of innate lymphocytes that responds to local, tissue-derived signals and initiates allergic immune responses. ILC2 activation promotes the recruitment of eosinophils, polarization of alternatively activated macrophages, and tissue-remodeling, processes associated with the 'weep and sweep' response to helminthic worm colonization and infection. ILC2

Denna uppsats undersöker synen på romer och resande i det svenska samhället mellan åren 1888 och 1904. Även användningen av begreppen zigenare och tattare undersöks i uppsatsen. Föreställningar om ras, etnicitet och upplevd exotism utgör uppsatsens centrala undersökningsområden. Uppsatsen undersöker tidningarna Arbetet och Sydsvenska Dagbladet Snällposten. Uppsatsens resultat visar att grupperna sThis paper examines the perception of Roma and Travelers in Swedish society between 1888 and 1904, including the use of terms "Zigenare" (Gypsy) and "Tattare" (Tinker). It explores notions of race, ethnicity, and perceived exotism. The study focuses on two newspapers, "Arbetet" and "Sydsvenska Dagbladet Snällposten," revealing that the groups referred to as

Celis and Childs have called for a ‘second generation’ of feminist scholarship on representation that foregrounds intersectional heterogeneity and emphasises responsiveness to representatives beyond parliaments. We build on these important contributions, arguing that second-generation feminist scholarship and democratic design can make the greatest gains by operationalising intersectionality in cl

Aims: An increase in psychosomatic symptoms among adolescents has recently been reported. Few studies have examined the relation between food intake and psychosomatic symptoms. The aim was to study the association between food intake and overall psychosomatic burden and separate psychosomatic symptoms. Methods: In this cross-sectional study, we used data from 6248 girls and 7153 boys in south-east

Incomplete wildfire combustion in boreal forests leaves behind legacy plant-soil feedbacks known to restrict plant biodiversity. These restrictions can inhibit carbon recapture after fire by limiting ecosystem transition to vegetation growth patterns that are capable of offsetting warmth-enhanced soil decomposition under climate change. Here, we field-surveyed plant regrowth conditions 2 years aft

This paper investigates a methodology for the precise statistical deconvolution of hardness properties within various metallic matrix multiphase materials. The central focus is on accurately characterizing mechanical behaviour in the context of complex materials. To meet these objectives, we implemented an approach involving nanoindentation analyses of the selected materials. This technique allowe

The performance of a transmission is instrumental to the performance of a vehicle’s powertrain. In the hypercar industry, where lap time performance has a larger influence on the design of vehicle components than in normal vehicles, the impact that the transmission has is further emphasized. One key parameter to understand and model is the efficiency of the transmission, which affects acceleration

Glypicans are linked to various aspects of neoplastic behavior, and their therapeutic value has been proposed in different cancers. Here, we have systematically assessed the impact of GPC4 on cancer progression through functional genomics and transcriptomic analyses across a broad range of cancers. Survival analysis using TCGA cancer patient data reveals divergent effects of GPC4 expression across

BakgrundVaccination är en av de viktigaste folkhälsoinsatserna för att rädda liv och hindra spridning av smittsamma sjukdomar. Tack vare vaccinationer har miljontals liv räddats världen över. Men det räcker inte att säkra och effektiva vaccin tas fram och tillgängliggörs. En förutsättning för framgångarna är att individer accepterar att bli vaccinerade. Under senare tid har forskningsområdet om vaThe vaccination coverage in Sweden's National Immunization Program (NIP) has been highand stable for decades. Although the coverage is high, few studies have assessed parental vaccineacceptance in Sweden. This doctoral thesis aimed to provide an in-depth understanding of currentparental vaccine acceptance, focusing particularly on Human papillomavirus (HPV) and measles, mumps and rubella (MMR) vac

Every living cell is surrounded by a cell membrane that is made up of amphipathicphospholipids, separating the aqueous solutions inside and outside the cell with ahydrophobic barrier. This compartmentalization is a prerequisite for life, but so arethe many molecules that are floating in the membrane, altering its properties andconnecting the inside with the outside. An important group are the tran

Probabilistic solvers provide a flexible and efficient framework for simulation, uncertainty quantification, and inference in dynamical systems. However, like standard solvers, they suffer performance penalties for certain stiff systems, where small steps are required not for reasons of numerical accuracy but for the sake of stability. This issue is greatly alleviated in semi-linear problems by th

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers with limited treatment options, illustrating an urgent need to identify new drugable targets in PDACs.OBJECTIVE: Using the similarities between tumor development and normal embryonic development, which is accompanied by rapid cell expansion, we aimed to identify and characterize embryonic signaling pathways that

We explain how the accelerating field amplitude and phase vary with modulator voltage in pulsed radio frequency high-power amplifiers based on klystron tubes. Changes in modulator voltage give rise to correlated changes of amplitude and phase, affecting the properties of the accelerated beam, in particular energy, arrival time, and bunch duration. We show, both theoretically and experimentally, th