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Consumption of ultra-processed food is associated with increased caloric intake and impaired health. Here, we conducted a nutrition trial (NCT05368194) with controlled, 2 × 2 crossover design and tested whether ultra-processed food impairs reproductive and metabolic fitness, with further aggravation by excess caloric intake. Comparing the response from an unprocessed to ultra-processed diet identi
Spray drying, a process which is widely used in the food industry, involves the atomizations of a liquid slurry into a drying chamber to produce a powder of desired properties. Although liquid viscosity strongly influences process efficiency, few studies have examined its effect on spray characteristics for specific system designs, where previous work has been hindered by experimental/numerical ch
Giving children with disabilities opportunities to explore how to use a powered mobility device is important for their development and learning. Encouraging and supporting exploration of how to set a device in motion and how to use it, has to be performed in harmony with each child and their abilities, needs and motivation. The experience of self-produced movement gives bodily feelings when action
Importance: Persistent disparities in mortality across countries suggest uneven improvements in living standards and access to life-extending health technologies, as well as context-specific obstacles. Studies have analyzed cross-country inequality in mortality but have not widely contextualized those disparities in terms of developmental progress relative to a frontier representing a level of mor
Ferroelectric thin films present a powerful platform for next-generation computing and memory applications. However, domain morphology and dynamics in buried ferroelectric stacks have remained underexplored, despite their importance for real device performance. Here, nanoprobe X-ray diffraction (nano-XRD) is used to image ferroelectric domains inside BiFeO3-based capacitors, revealing local disord
Certifying solvers have long been standard for decision problems in Boolean satisfiability (SAT), allowing for proof logging and checking with very limited overhead, but developing similar tools for combinatorial optimization has remained a challenge. A recent promising approach covering a wide range of solving paradigms is pseudo-Boolean proof logging, but this has mostly consisted of proof-of-co
In this issue of Cell Stem Cell, Márquez-Valadez, Gallardo-Caballero, and Llorens-Martín1 report that adult hippocampal neurogenesis (AHN) is differentially disrupted in neuropsychiatric disorders. Their findings highlight the role of the neurogenic niche and lifestyle, supporting the view of human AHN as a dynamic process sensitive to biology and behavior.
Transfecting clonal beta cells with large DNA plasmids holds significant promise for diabetes research. Existing transfection techniques like lipofection, viral transduction, and bulk electroporation often face limitations such as low efficiency and cytotoxicity. Nanoelectroporation, which utilizes nanopores or nanostraws and the application of mild electrical pulses, offers a gentle and safe alte
In the physical product development context, agile practices, particularly agile teams, are seldom applied as originally intended. They are often equated with traditional project teams, which conflicts with the fundamental principles of agile teams, undermining several associated benefits. Unlike traditional project teams, agile teams are ideally stable, focusing on continuously delivering value t
The thermal regime is a key indicator of permafrost evolution and thaw trajectories in response to climate change but remains poorly represented in global models. In this study, we applied the Moving-Grid Permafrost Model (MGPM), an efficient numerical model, to simulate the permafrost thermal regime in West Kunlun (WKL), a 55 669 km2 region on the remote northwestern Qinghai-Tibet Plateau charact
Rationally designing and fabricating high-performance core–shell nanostructures for catalytic organic synthesis is significant yet challenging. Here, we report a solvothermal/calcination strategy to prepare novel core–shell iron–aluminum oxide (FeAlOx) nanosphere-based nanoreactors incorporating active heterometals (AHM = Pd, Cu, or Mn). Leveraging the synergistic benefits of their unique core–she
The implementation of low-carbon futures requires both the assembling of new technologies, and practices, as well as the ‘unmaking’ of extant high-carbon infrastructures. Here, we bring together geographical, STS, anthropological, and sociological thinking on time to re-conceptualise such processes of unmaking. We argue that a focus on temporalities is especially pertinent to the unmaking of mater
Designkort för mobil utvecklingDesign cards supporting mobile development
Poster som illustrerar mobil användningPoster illustrating mobile user experiences
Background: People with hemophilia (PwH) or von Willebrand disease (VWD) are at risk of joint bleeding, which can lead to hemophilic arthropathy. Point-of-care musculoskeletal ultrasound (POC-MSKUS) is increasingly used to detect joint bleeds, but a comprehensive compilation of available independent scanning protocols and their respective measurement properties is missing. Objectives: This study a
Using structural properties of groups of small order, we establish the non-existence of varieties isogenous to a higher product of dimension n greater than 3 with fixed topological Euler number (-2)n and trivial first Betti number.
This paper examines the causal effect of public discourse in one or both sides of themarket on overall market socially responsible behavior. In a laboratory setting, wevary whether firms and/or consumers participate in a public discussion before tradingbegins. When both sides take part, the share of socially responsible trades increasesslightly; however, when only one side participates, market soc
