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Vulnerability and stressors on the pathway to depression in a global cohort of young athletics (track and field) athletes

This research set out to identify pathways from vulnerability and stressors to depression in a global population of young athletes. Retrospective data were collected at age 18–19 years from Athletics athletes (n = 1322) originating from Africa, Asia, Europe, Oceania, and the Americas. We hypothesised that sports-related and non-sports-related stressors in interaction with structural vulnerability

Resonant Frequency Ultrasonic P-Waves for Evaluating Uniaxial Compressive Strength of the Stabilized Slag–Cement Sediments

Marina sediment kan stabiliseras med ultrahöghållfasta bindemedel: cement, Cement Kiln Dust (CKD) och slagg. Egenskaperna hos den stabiliserade jorden indikerar potential för återanvändning. Den här studien undersökte prestandan för den enaxiella tryckhållfastheten (UCS) i smarina sediment stabiliserade med bindemedel (cement, CKD, slagg), testade med ultraljuds P-vågor. Material omfattar 194 prov

Geochemical tests to study the effects of cement ratio on potassium and TBT leaching and the pH of the marine sediments from the Kattegat Strait, Port of Gothenburg, Sweden

Cement är ett viktigt byggmaterial inom anläggnings- och geoteknik. Men dess tillämpningar för stabilisering av marina sediment behöver ytterligare undersökas. Denna artikel undersöker effekterna av olika mängder portlandcement tillsatt till sedimentprover vid urlakning av tributyltenn (TBT) från det förorenade marina sedimenterar och utvärderar pH-nivån. Identifiera de bästa kombinationerna av Po

Evaluating Swedish soldiers’ physiological demands in combat

Att vara soldat är väldigt fysiskt krävande, det viktigt att upprätthålla en god fysisk kapacitetsnivå för att klara sin tjänst. Vid militära operationer arbetar soldater på lägre fysiska kravnivåer under lång tid för att ibland gå upp på intensiva kravnivåer. Framgång vid militära operationer är ofta beroende på soldaternas fysiska kapacitet, rörlighet och förmågan att bära sin utrustning. Det är

The gender-resilience nexus in peace building : the quest for sustainable peace

Resilience and gender have become new buzzwords for expressing renewal in peacebuilding. This article unpacks the gender-resilience nexus in theory and analyses global trends and variation in peacebuilding policy and practice. It advances an analytical framework based on three central pillars of peacebuilding: process, outcome, and expertise. A comprehensive analysis of 49 international peacebuild

Short-lasting conditioned stimulus applied to the middle cerebellar peduncle elicits delayed conditioned eye blink responses in the decerebrate ferret

In delay eye blink conditioning, the conditioned stimulus (CS) ends at the time of the unconditioned stimulus (US). If the CS duration is decreased, there will be a 'trace' period with no ongoing CS before the onset of the US. During this period some neural activity has to continue after the CS offset to: (i) permit association between the CS and the US; and (ii) elicit a conditioned response appe

Bilateral disruption of conditioned responses after unilateral blockade of cerebellar output in the decerebrate ferret

1. Lesions of the cerebellar cortex can abolish classically conditioned eyeblink responses, but some recovery with retraining has been observed. It has been suggested that the recovered responses are generated by the intact contralateral cerebellar hemisphere. In order to investigate this suggestion, bilaterally acquired conditioned responses were studied after the unilateral blockade of cerebella

InGaAs Nanowire and Quantum Well Devices

To fulfill the increasing demand for high-speed electronics used for computation or communication is one everlasting challenge for the semiconductor industry. Emerging fields such as quantum computation also has a need for circuits operating at cryogenic temperatures. The metal-oxide-semiconductor field-effect transistor (MOSFET) is the main component in modern electronics, traditionally fabricate

Effect of ethanol on the excitability of the inferior olive in decerebrate ferret

Climbing fibers, which originate in the inferior olive and project to Purkinje cells and Golgi cells in the cerebellar cortex, were activated at low (0.4-Hz) and high (4-Hz) frequencies by peri-orbital stimulation in decerebrate ferrets. Climbing fiber responses were recorded as field potentials from the c3 zone of the cerebellar surface. When periorbital stimulation was applied at high frequency,

Conditioned eyeblink response consists of two distinct components

The aim of these experiments was to obtain a detailed knowledge of how the orbicularis oculi muscle is activated during the execution of a conditioned eyeblink response (CR). This is the first critical step to understand the underlying neural mechanisms involved in the control of the CR. Decerebrate ferrets were trained in a classical conditioning paradigm. The conditioned stimulus (CS) was a trai

Effect of varying the intensity and train frequency of forelimb and cerebellar mossy fiber conditioned stimuli on the latency of conditioned eye- blink responses in decerebrate ferrets

To study the role of the mossy fiber afferents to the cerebellum in classical eye-blink conditioning, in particular the timing of the conditioned responses, we compared the effects of varying a peripheral conditioned stimulus with the effects of corresponding variations of direct stimulation of the mossy fibers. In one set of experiments, decerebrate ferrets were trained in a Pavlovian eye-blink c

Plasma matrix metalloproteinase 2 is associated with severity and mortality in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by vasoconstriction and remodeling of the pulmonary vessels. Risk stratification in PAH could potentially be improved by including novel biomarkers related to PAH pathobiology. We aimed to investigate the relationship between extracellular matrix (ECM)-related proteins, survival, and European Society of Cardiology an

Myocardial perfusion by CMR coronary sinus flow shows sex differences and lowered perfusion at stress in patients with suspected microvascular angina

Background: Patients with chest pain may have normal coronary arteries and suffer from microvascular angina (MVA). The aim of this study was to determine if patients with suspected MVA have lower global myocardial perfusion (global MP) during adenosine stress compared with healthy controls and coronary artery disease (CAD) patients and to determine if there are sex differences in global MP. Method

In situ microstructural evolution of spruce wood during soda pulping using synchrotron X-ray tomography

A new laboratory reactor to perform in situ studies of structural changes in wood during soda pulping using synchrotron X-ray tomography is presented. The reactor is of recirculation type to provide stable reaction conditions and mimic the industrial situation. Experiments have been performed using this reactor in situ at a synchrotron microtomography beamline to provide sequences of 3D images fro

Energy-Efficient Application-Specific Instruction-Set Processor for Feature Extraction in Smart Vision Systems

Smart vision sensor systems enable many computer vision applications such as autonomous drones and wearable devices. These battery-powered gadgets have very stringent power consumption requirements. Close-to-sensor feature extraction compressing the full image into descriptive keypoints, is crucial as it allows for several design optimizations. First, the amount of necessary on-chip memory can be

Release of moth pheromone compounds from Nicotiana benthamiana upon transient expression of heterologous biosynthetic genes

Background: Using genetically modified plants as natural dispensers of insect pheromones may eventually become part of a novel strategy for integrated pest management. Results: In the present study, we first characterized essential functional genes for sex pheromone biosynthesis in the rice stem borer Chilo suppressalis (Walker) by heterologous expression in Saccharomyces cerevisiae and Nicotiana

Comorbidities in hereditary angioedema—A population-based cohort study

Background: In hereditary angioedema (HAE), low levels (type 1) or defect in function (type 2) of the serine-protease inhibitor C1 Inhibitor protein results in activation of the classical pathway of the complement system as well as the contact system. Here, we investigated the risk of comorbidities in HAE. Methods: Individuals with HAE (n = 239; identified through a physician made diagnosis) and a

Associations Between Physical Activity, Self-reported Joint Function, and Molecular Biomarkers in Working Age Individuals With Hip and/or Knee Osteoarthritis

Objective: Previous research has suggested an association between physical activity (PA), joint function, and molecular biomarkers, but more studies are needed. The aim of this study was to explore the associations between PA or self-reported joint function and molecular biomarkers of cartilage and inflammation in individuals with hip and/or knee osteoarthritis (OA). Specific objectives were to ex