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Background: The assessment of serum neurofilament light chain (sNFL) has emerged as a diagnostic and prognostic tool in monitoring multiple sclerosis (MS). However, the application of periodic measurement in daily practice remains unclear. Objective: To evaluate the predictive value of individual sNFL levels in determining disease activity in patients with relapsing MS (RMS). Methods: In this two-

Punch biopsies are commonly used in dermatology for diagnosing skin diseases. Traditional methods involve the use of forceps, skin hooks, and scissors, which add to health care costs. The technique described here offers a cost-effective and efficient alternative for obtaining specimens.

Sex education can impact pupils’ sexual activity and convey the social norms regarding family formation and responsibility, which can have significant consequences to their future. To investigate the life-cycle effects of social norm transmission, this study draws on the introduction of comprehensive sex education in the curriculum of Swedish primary schools during the 1940s to the 1950s. Inspired

This thesis investigates the question ‘What is knowledge?’ In intuition-based epistemology the question is often considered to concern how ‘knowledge’ is used linguistically or conceptually rather than what knowledge is. In addition, since intuitions are used as evidence despite empirical experiments indicating that people’s intuitions vary a great deal and that little conclusive systematicity can

Reliable maps of species distributions are fundamental for biodiversity research and conservation. The International Union for Conservation of Nature (IUCN) range maps are widely recognized as authoritative representations of species’ geographic limits, yet they might not always align with actual occurrence data. In recent area of habitat (AOH) maps, areas that are not habitat have been removed fr

Background and objective: To assess the effect of surgeon sex on short- and long-term outcomes after colon cancer resections. Methods: Clinical data of patients who underwent colon cancer resections between 2010 and 2020 at Helsingborg Hospital, Sweden, were retrospectively obtained from medical records. The sex of the surgeon of each procedure was recorded. Morbidity, mortality, and long-term sur

Introduction: Planning cranioplasty (CPL) in patients with suspected or proven post-traumatic hydrocephalus (PTH) poses a significant management challenge due to a lack of clear guidance. Research question: This project aims to create a European document to improve adherence and adapt to local protocols based on available resources and national health systems. Methods: After a thorough non-systema

Bridges are an important part of the traffic infrastructure, which are subjected to high safety requirements and economic consequences in case of functionality failure. Therefore, it is needed to consider potentially substantial direct and indirect risks during service life, i.e., the need for risk and robustness analyses. Over the last decades, various quantitative performance criteria have been

The main objective of this paper is to develop a readiness index model that can serve as an analytical tool for exploring the achievements of the electrification of transportation systems. We have applied this readiness index model to evaluate the readiness positioning of China, Norway, and Sweden towards transportation electrification. We have chosen these three countries as they represent divers

Chronic obstructive pulmonary disease (COPD) is commonly caused from smoking cigarettes that induce biological stress responses. Previously we found disorganized endoplasmic reticulum (ER) in fibroblasts from COPD with different responses to chemical stressors compared to healthy subjects. Here, we aimed to investigate differences in stress-related gene expressions within lung cells from COPD and

There are likely many undiscovered impact structures on Earth, but several challenges prevent their detection, including possible concealment beneath large ice sheets. In recent years, geophysical, geochemical, and microphysical evidence has mounted for a ca. 58 Ma impact structure under the Hiawatha Glacier, northwest Greenland. Here, we report evidence for a second, much older hypervelocity impa

Determination of spatial position of the upper forest line in Khibiny mountains is important to assess its dynamics caused by global environmental changes. Through analysis of high-resolution satellite images and application of the cartographical method we have determined the position of the forest line and its spatial variations, and explained factors influencing its position. This study has resu