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Why are some people with obesity protected from type 2 diabetes? Who is at risk of developing gestational diabetes and type 2 diabetes? The Hjelt Diabetes Foundation awards two diabetes researchers at Lund University Diabetes Centre grants for projects that are seeking new answers to these questions. Gestational diabetes happens when the body cannot produce enough insulin during pregnancy. The con

https://www.ludc.lu.se/article/research-obesity-and-gestational-diabetes-receive-support-hjelt-diabetes-foundation - 2025-12-01

People with a hereditary risk of obesity lose as much weight as a result of better diet, exercise and weight loss drugs as the rest of the population, according to an international study presented in The BMJ. “This indicates that even in people at genetic risk of obesity, lifestyle change is an effective way to lose weight”, says Professor Paul Franks of Lund University in Sweden, one of the resea

https://www.ludc.lu.se/article/no-link-between-obesity-gene-and-intentional-weight-loss - 2025-12-01

Interest in type 1 diabetes screening is growing as methods improve and new treatments become available to more patients. New research at Lund University demonstrates how screening for autoimmune diseases can be carried out on a large-scale basis. A new treatment that can delay the onset of type 1 diabetes has been approved for use in the United States. If the treatment Teplizumab becomes availabl

https://www.ludc.lu.se/article/new-method-allows-large-scale-screening-autoimmune-diseases - 2025-12-01

The EAT-Lancet diet is a framework designed to promote environmental sustainability while also preventing common diseases such as type 2 diabetes. How do we know if the diet actually works? An international research team studied seven dietary scores and found that two of them were particularly good at evaluating adherence to the diet. Reliable diet scores are important when developing sustainable

https://www.ludc.lu.se/article/research-paves-way-sustainable-dietary-recommendations - 2025-12-01

The dream of finding the “diabetes gene” is dead. However, partly thanks to Leif Groop – professor and multiple award recipient for his ground-breaking research – we will look at type 2 diabetes in a whole new way in the future. He is now retiring, and in an interview with diabetesportalen.se he looks back on his eventful career in research. The study that since 2006 has been the central hub of th

https://www.ludc.lu.se/article/time-burie-lada-interview-leif-groop - 2025-12-01

Researchers at Lund University in Sweden have discovered that the appetite hormone CART is regulated by glucose and is found in greater quantity in people with type 2 diabetes. “This could be the body’s own defence mechanism to lower blood sugar levels in case of type 2 diabetes”, says Associate Professor Nils Wierup, in charge of the study. The study shows that the appetite hormone CART not only

https://www.ludc.lu.se/article/antidiabetic-effects-discovered-appetite-hormone-cart - 2025-12-01

Heart attack and stroke are common complications of diabetes, as the body's ability to repair and form vessels is impaired. Researchers at Lund University have developed a new substance with the capacity to stimulate vascular repair response and the formation of vessels. In diabetes, the body's ability to repair vascular damage caused by the disease is impaired, which can lead to complications suc

https://www.ludc.lu.se/article/new-peptide-may-reduce-risk-diabetes-complications - 2025-12-01

Precision medicine seeks to reduce errors and improve accuracy in medical and health recommendations, but better evidence is needed to fulfil its potential. An international consortium led by Paul Franks at Lund University presents new guidelines that may increase the clinical relevance of precision medicine research. An international consensus report on precision medicine that was published in Na

https://www.ludc.lu.se/article/new-guidelines-aim-increase-accuracy-precision-medicine-research - 2025-12-01

During his more than 50-year career, diabetes researcher Åke Lernmark has made several significant discoveries that have increased knowledge about type 1 diabetes. His research contributes to creating conditions for a national screening programme in Sweden. In Sweden, around 1,000 children and an equal number of adults develop type 1 diabetes each year. The disease has major consequences for the f

https://www.ludc.lu.se/article/scientist-who-paving-way-screening-type-1-diabetes - 2025-12-01

People with type 2 diabetes have a higher risk of developing cardiovascular disease and dying prematurely due to atherosclerosis. A research team at Lund University in Sweden has now identified molecular mechanisms that may explain the increased risk. Their discovery may lead to more accurate treatments for patients with atherosclerosis and type 2 diabetes in the future. People with type 2 diabete

https://www.ludc.lu.se/article/new-explanation-dangerous-atherosclerotic-plaques-type-2-diabetes - 2025-12-01

Obesity is a common cause of diabetes, heart disease and early death, but risk differs greatly from one person to the next. In work led by researchers at Lund University in Sweden as part of the Innovative Medicine Initiative project SOPHIA, a pioneering clinical risk prediction algorithm has been developed that splits obesity into 5 separate diagnostic profiles each with contrasting health conseq

https://www.ludc.lu.se/article/new-precision-medicine-approach-helps-detect-subgroups-people-obesity-high-risk-diabetes-and-heart - 2025-12-01

Diabetes researcher Joao Duarte specialices in studying what happens in the brain in diabetes. In his research, he is also investigating how diet changes can improve brain function in connection with diabetes. He will be awarded this year's Medeon stipend on the World Diabetes Day Skåne event in Malmö on November 14. "I hope that my research can contribute to an increased awareness of the importan

https://www.ludc.lu.se/article/praised-research-diabetes-and-dementia - 2025-12-01

In 2025, children within the TEDDY study will submit their final samples at research clinics in Sweden, Finland, Germany and the United States. The international study has provided a lot of new knowledge about type 1 diabetes and how the disease develops. Analysis of the samples will continue with the aim of preventing the disease. Sweden and Finland are the two top countries for incidence rates o

https://www.ludc.lu.se/article/new-knowledge-about-type-1-diabetes-large-scale-teddy-study-will-soon-be-completed - 2025-12-01

In type 2 diabetes, the body's ability to release insulin is impaired, which leads to high blood glucose levels. Research led from Lund University shows how the levels of a particular protein are elevated in the pancreas of people with type 2 diabetes. By knocking out the gene for the protein IGFBP7, the researchers discovered that insulin secretion was improved. Reduced insulin secretion leads to

https://www.ludc.lu.se/article/protein-affects-ability-secrete-insulin-type-2-diabetes - 2025-12-01

This year's recipient of the Leif C. Groop Award for Outstanding Diabetes Research maps out mechanisms in the adipose tissue, which has increased the understanding of why some people with obesity develop type 2 diabetes. Ingrid Wernstedt Asterholm at University of Gothenburg is spurred to find new answers when observations in the lab do not agree with the general view. Justification for awarding"I

https://www.ludc.lu.se/article/ingrid-wernstedt-asterholm-receives-leif-c-groop-award-research-adipose-tissue - 2025-12-01

Ingrid Wernstedt Asterholm received the Leif C. Groop Award for Outstanding Diabetes Research at the annual LUDC Diabetes Research Day. "This award allows me to rest in the feeling that all the work I have done is good enough, at least for a short while,” said the recipient. Ingrid Wernstedt Asterholm at Sahlgrenska Academy at University of Gothenburg is this year’s recipient of the Leif C. Groop

https://www.ludc.lu.se/article/diabetes-event-highlighted-findings-may-lead-new-treatments - 2025-12-01

A large international study has identified three different pathways towards type 1 diabetes in children. Researchers at Lund University Diabetes Centre have contributed with data from a prospective study in southern Sweden. An important objective with the study published in Nature Communications is to gain a better understanding of how the disease develops to be able to take preventive measures. “

https://www.ludc.lu.se/article/large-international-study-points-three-pathways-towards-type-1-diabetes - 2025-12-01

Researchers at Lund University have discovered increased levels of a microRNA in type 2 diabetes, which has a negative effect on insulin secretion. Their experiments on human insulin producing cells in the pancreas also demonstrate that it is possible to increase the insulin secretion by reducing the levels of this microRNA. An important goal of the research is to develop new treatments for people

https://www.ludc.lu.se/article/newly-discovered-drug-candidate-increases-insulin-secretion-type-2-diabetes - 2025-12-01

Obesity and excess weight increase the risk of developing type 2 diabetes, but individuals of normal weight can also develop the disease. Researchers at Lund University have discovered that it is possible to identify at-risk individuals by measuring BMI in a new way. The authors of the study have identified metabolic alterations associated with obesity that can increase the risk of developing type

https://www.ludc.lu.se/article/new-way-measuring-bmi-can-predict-risk-type-2-diabetes-individuals-normal-weight - 2025-12-01

A new study by researchers at Lund University supports the notion that patients with type 2 diabetes should be divided into subgroups and given individualised treatment. The study demonstrates that there are distinct epigenetic differences between different groups of patients with type 2 diabetes. The epigenetic markers were also associated with different risks of developing common complications i

https://www.ludc.lu.se/article/epigenetic-markers-predict-complications-patients-type-2-diabetes - 2025-12-01