Published 9 September 2021 Photo: Pixabay / Gerd Altmann In this paper, we describe the use of the target trial framework for designing agent-based models when the goal is estimation of causal effects in the presence of interference, or spillover. Read the paper at https://academic.oup.com/aje/article/190/8/1652/6140873

https://www.lupop.lu.se/article/emulating-target-trials-improve-causal-inference-agent-based-models - 2025-03-12

Published 9 September 2021 Photo: Pixabay / Arek Socha This registry is expected to provide insights into the long-term durability of different strategies of surgical repair for TAAD. Read the paper at https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019…

https://www.lupop.lu.se/article/european-registry-type-aortic-dissection-ertaad-rationale-design-and-definition-criteria - 2025-03-12

Published 10 September 2021 To extend previous simulations on the performance of propensity score (PS) weighting and trimming methods to settings without and with unmeasured confounding, Poisson outcomes, and various strengths of treatment prediction (PS c statistic), we simulated studies with a binary intended treatment T as a function of 4 measured covariates. Read the paper at https://academic.

https://www.lupop.lu.se/article/propensity-score-weighting-and-trimming-strategies-reducing-variance-and-bias-treatment-effect - 2025-03-12

Published 25 May 2018 Hormonal factors and pancreatic cancer risk in women: The Malmo Diet and Cancer Study Read it here!

https://www.lupop.lu.se/article/new-publication-malmo-diet-and-cancer-study - 2025-03-12

Published 10 September 2021 Photo: Pixabay / geralt Simulation is an important tool within epidemiology for both learning and developing new methodology. Unfortunately, few epidemiology training programs teach basic simulation methods. Read the paper at https://academic.oup.com/aje/article/190/8/1696/6140874

https://www.lupop.lu.se/article/simulation-practice-balancing-intercept - 2025-03-12

Published 11 September 2021 Photo: Pixabay / VSRao The benefits of using data from national registers as endpoints in epidemiological studies must be weighed against the impact of potentially decreased data quality. Read the paper at https://journals.sagepub.com/doi/full/10.1177/14034948211021191

https://www.lupop.lu.se/article/data-national-health-registers-endpoints-tromso-study-correctness-and-completeness-stroke-diagnoses - 2025-03-12

Published 11 September 2021 Unmeasured confounding is a common threat to the validity of observational studies. In practice, confounding bias may arise from both confounders that are completely unmeasured and from confounders that are measured with error. Read the paper at https://academic.oup.com/ije/article/50/3/711/6048186

https://www.lupop.lu.se/article/cautionary-note-recently-proposed-sensitivity-analysis-unmeasured-confounding - 2025-03-12

Published 12 September 2021 Photo: Pixabay / Brian Merrill We explored the comparability of anxiety measures from register- and survey-based data including analyses of prevalence and associations with selected psychiatric and somatic diseases. Read the paper at https://onlinelibrary.wiley.com/doi/full/10.1111/acps.13339

https://www.lupop.lu.se/article/use-register-and-survey-based-measures-anxiety-population-based-danish-cohort - 2025-03-12

Published 12 September 2021 Photo: Pixabay / Gerd Altmann Immeasurable time bias exaggerates drug benefits in pharmacoepidemiological studies due to exposure misclassification arising from the inability to measure in-hospital medications in many health care databases. Read the paper at https://academic.oup.com/ije/article/50/3/987/6048410

https://www.lupop.lu.se/article/analytical-approaches-minimizing-immeasurable-time-bias-cohort-studies - 2025-03-12

Published 13 September 2021 Interrupted time-series (ITS) designs are a robust and increasingly popular non-randomized study design for strong causal inference in the evaluation of public health interventions. Read the paper at https://academic.oup.com/ije/article/50/3/1011/5937253

https://www.lupop.lu.se/article/reflection-modern-methods-common-error-segmented-regression-parameterization-interrupted-time-series - 2025-03-12

Published 13 September 2021 Photo: Pixabay / www_slon_pics We report the current status of CKD registries in Europe in relation to their data collection on patients not on KRT so that in the future we may investigate to what extent also their data may be used for similar purposes, like collaborative research on CKD trajectories and patient outcomes. Read the paper at https://academic.oup.com/ndt/a

https://www.lupop.lu.se/article/snapshot-european-registries-chronic-kidney-disease-patients-not-kidney-replacement-therapy - 2025-03-12

Published 14 September 2021 Photo: Pixabay / Gerd Altmann The aim of this study was to explore the potential misclassification and evaluate the completeness of esophageal cancer diagnoses in the FCR and HILMO, considering misclassification. Read the paper at https://www.tandfonline.com/doi/full/10.1080/0284186X.2020.1792547

https://www.lupop.lu.se/article/completeness-esophageal-cancer-diagnosis-finnish-cancer-registry-and-hospital-discharge-registry - 2025-03-12

Published 14 September 2021 Photo: pixabay The term of overadjustment bias is used to refer to different scenarios. Here, we propose a unified definition of overadjustment, with four types. Read the paper at https://journals.lww.com/epidem/Fulltext/2021/09000/Revisiting_Overadju…

https://www.lupop.lu.se/article/revisiting-overadjustment-bias - 2025-03-12

Published 15 September 2021 Photo: Pixabay / Gerd Altmann General population-based cohort studies provide solid evidence on mass Helicobacter pylori (HP) eradication effects. Self-reported questionnaires are occasionally used in such studies to ascertain the HP eradication history. However, reports on the reliability of these questionnaires are lacking. Read the paper at https://www.nature.com/art

https://www.lupop.lu.se/article/reliability-self-reported-questionnaire-epidemiological-investigation-helicobacter-pylori - 2025-03-12

Published 25 May 2018 Forskningsrådet Formas lanserar en ny satsning på forskning för en giftfri miljö, specifikt till projekt som kan öka kunskapen kring kombinationseffekter av kemikalier och substanser. Läs mer här.

https://www.lupop.lu.se/article/giftfri-miljo-i-fokus-ny-forskningssatsning - 2025-03-12

Published 15 September 2021 Photo: Pixabay / Ben Kerckx A cardiovascular mortality algorithm applied to administrative health records had moderate validity when compared to vital statistics data. Substantial variation existed across study sites representing different geographic locations and two healthcare systems. These variations may reflect different diagnostic coding practices and healthcare u

https://www.lupop.lu.se/article/validity-algorithm-identify-cardiovascular-deaths-administrative-health-records-multi-database - 2025-03-12

Published 16 September 2021 This commentary provides a practical perspective on epidemiological analysis within a single high-dimensional study of moderate size to consider a causal question. Read the paper at https://academic.oup.com/ije/article/50/3/1016/6140018

https://www.lupop.lu.se/article/reflection-modern-methods-building-causal-evidence-within-high-dimensional-molecular-epidemiological - 2025-03-12

Published 16 September 2021 Photo: Pixabay / Sasin Tipchai The value of accurate healthcare data has never been more apparent than during the past year, and there is increasing recognition of the important role surgical registries play in driving improved patient outcomes, patient safety, and academic research. Successful registries need to be responsive and adapt to the rapidly changing clinical

https://www.lupop.lu.se/article/future-surgical-registries - 2025-03-12

Published 17 September 2021 Photo: Pixabay / Gerd Altmann Molecular pathological epidemiology research provides information about pathogenic mechanisms. A common study goal is to evaluate whether the effects of risk factors on disease incidence vary between different disease subtypes. Read the paper at https://academic.oup.com/ije/article/50/3/1030/6114706

https://www.lupop.lu.se/article/reflection-modern-methods-causal-inference-considerations-heterogeneous-disease-etiology - 2025-03-12

Published 23 February 2017 Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research from Lund University, Sweden. In a new study, doctoral student Cajsa Davegårdh has studied so-called DNA methylation in muscle stem cells in both obese and non-obese individuals. D

https://www.ludc.lu.se/article/obesity-reprogrammes-muscle-stem-cells - 2025-03-12