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Estimates from Mendelian randomization studies of unrelated individuals can be biased due to uncontrolled confounding from familial effects. Here we describe methods for within-family Mendelian randomization analyses and use simulation studies to show that family-based analyses can reduce such biases. Read more here.
McMaster GRADE Centre researchers developed ‘health outcome descriptors’ for standardizing descriptions of health outcomes and overcoming these problems to support the European Commission Initiative on Breast Cancer (ECIBC) Guideline Development Group (GDG). We aimed to determine which aspects of the development, content, and use of health outcome descriptors were valuable to guideline developers.
https://www.lupop.lu.se/article/development-and-use-health-outcome-descriptors-guideline-development-case-study - 2025-12-13
Objectives: To investigate use of data from a clinical quality registry for cardiac rehabilitation in Denmark, considering the extent to which data are used for local quality improvement and what facilitates the use of these data, with a particular focus on whether there are differences between frontline staff and managers. Read more here.
Combining National Quality Registries (NQRs) with existing National Health Registries (NHRs) might make it possible to get a wider picture of older adults health situation. The aim was to examine the feasibility of aggregating data across different NQRs and existing NHRs to explore the possibility to investigate trajectories and patterns of disease and care, specifically for the most ill older adu
Forte har påbörjat en översyn av ett antal mindre bidragsformer. Under 2020 sker därför ingen utlysning av nätverksbidrag, tidskriftsbidrag, konferensbidrag och gästforskarbidrag. Läs mer på https://forte.se/nyhet/ingen-utlysning-av-natverksbidrag-gastforskarbid….
Whether you’re starting a review article or your dissertation, embarking on a literature review can feel daunting. Not sure where to start? Join our webinar to learn how to tackle literature reviews with confidence. Read more here.
https://www.lupop.lu.se/article/web-science-webinar-your-essential-guide-literature-reviews - 2025-12-13
Med anledning av coronakrisen deltar Forte i Formas akututlysning för 2020. Utlysningen ska ge möjlighet att samla in forskningsmaterial av akut karaktär för att säkerställa framtida tillgänglighet för forskning. Forskare inom Fortes områden kan ansöka om medel för datainsamling med koppling till coronapandemin. Läs mer på https://forte.se/utlysning/akututlysning-2020.
https://www.lupop.lu.se/article/corona-akut-utlysning-2020 - 2025-12-13
Generalized linear models (GLMs) are often used with binary outcomes to estimate odds ratios. Though not as widely appreciated, GLMs can also be used to quantify risk differences, risk ratios, and their appropriate standard errors (1). Here, we illustrate how GLMs can be used to quantify these latter effect measures, and we demonstrate how to obtain valid standard errors. Read more at https://doi.
https://www.lupop.lu.se/article/estimating-risk-ratios-and-risk-differences-using-regression - 2025-12-13
There has been much debate about the relative emphasis of the field of epidemiology on causal inference. We believe this debate does short shrift to the breadth of the field. Epidemiologists answer myriad questions that are not causal and hypothesize about and investigate causal relationships without estimating causal effects. Descriptive studies face significant and often overlooked inferential a
https://www.lupop.lu.se/article/epidemiologic-toolbox-identifying-honing-and-using-right-tools-job - 2025-12-13
Read more at https://journals.plos.org/plosone/article?id=10.1371/journal.pone.02340….
Read more at https://pubmed.ncbi.nlm.nih.gov/32639513/.
Read more at https://doi.org/10.1002/sim.8672.
Breastfeeding in public continues to be contentious with qualitative evidence confirming that women face many challenges. It is therefore important to gain understanding of not only the challenges but also what women perceive is helpful to breastfeed in public. Read more at https://doi.org/10.1186/s13006-020-00281-0.
The main categories of data collected include: demographics, care visits, other encounters, clinical data, visit-level costs, resources and occupancy. Clinical images, patient-generated data, genetics and visits outside Halland are not included in the platform. Read more at https://doi.org/10.1093/ije/dyz262.
https://www.lupop.lu.se/article/data-resource-profile-regional-healthcare-information-platform-halland-sweden - 2025-12-13
We argue that the causal implications of this independence assumptions are highly unrealistic, and that a causal interpretation of the extended Kaplan–Meier curve is therefore typically unwarranted. Read more at https://journals.lww.com/epidem/FullText/2020/07000/A_Cautionary_Note_o….
https://www.lupop.lu.se/article/cautionary-note-extended-kaplan-meier-curves-time-varying-covariates - 2025-12-13
Read more at https://europepmc.org/article/med/32222650.
A Bayesian Approach to Validation Substudy Design With Prospective Data Collection Read more at https://journals.lww.com/epidem/Fulltext/2020/07000/Adaptive_Validation….
https://www.lupop.lu.se/article/adaptive-validation-design - 2025-12-13
Atrophy of Ch4 precedes and predicts future dementia in PD and is followed by changes in Ch1/Ch2, reflecting a posterior-anterior pattern of basal forebrain atrophy. Read more at https://doi.org/10.1016/j.nbd.2020.104831.
Read more at https://journals.lww.com/epidem/Fulltext/2020/07000/Reducing_Bias_Due_t….
Read more at https://doi.org/10.1016/j.jad.2020.03.090.
