Introduction: The Hip disability and Osteoarthritis Outcome Score (HOOS) was constructed in Sweden; this questionnaire has proved to be valid for persons with hip disability with or without hip osteoarthritis (OA) and with high demands of physical function. Objective: The objective of this study was to evaluate the internal consistency, reliability, construct validity, and floor and ceiling effect

Ethics committees approved human and animal study components; informed written consent was provided (prospective human study [20 men; mean age, 62 years]) or waived (retrospective human study [16 men, four women; mean age, 59 years]). The purpose of this study was to prospectively evaluate a clinically applicable method, accounting for the partial volume effect, to automatically quantify myocardia

Forty-five female outpatients sexually abused in childhood were offered a 2-year phase-divided group therapy. Before and after treatment and at 12 months follow-up, they answered questionnaires designed to elicit responses concerning psychological symptoms (Symptom Checklist; SCL-90) and sense of coherence (SOC). Symptoms for posttraumatic stress disorder (PTSD) were assessed before and after trea

Background: The Mediterranean diet has been suggested to play a beneficial role for health and longevity. However, to our knowledge, no prospective US study has investigated the Mediterranean dietary pattern in relation to mortality. Methods: Study participants included 214 284 men and 166 012 women in the National Institutes of Health (NIH)-AARP ( formerly known as the American Association of Ret

We have investigated the inhibition of the recently identified family C13 cysteine peptidase, pig legumain, by human cystatin C. The cystatin was seen to inhibit enzyme activity by stoichiometric 1:1 binding in competition with substrate. The Ki value for the interaction was 0.20 nM, i.e. cystatin C had an affinity for legumain similar to that for the papain-like family C1 cysteine peptidase, cath

Work from our laboratories has shown that the major antigenic determinants for rheumatoid factors (RFs) are in the C gamma 2-C gamma 3 interface region of IgG in the same area that binds staphylococcal protein A (SPA). Furthermore, the Fc binding proteins of groups A, C and G streptococci as well as the Fc binding proteins induced on cell surfaces by herpes simplex virus type I also bind to the sa

Ro 25-1553 is a metabolically stable analogue of endogenous vasoactive intestinal polypeptide (VIP). This compound is a potent bronchodilator in vitro as well as in vivo. Moreover, Ro 25-1553 has been shown to be highly selective of the VPAC2 receptor. We assessed the effect of Ro 25-1553 on isolated human bronchi and pulmonary arteries in vitro. Macroscopically normal human airways and pulmonary

Drying is one of the most energy intensive and common operations in the chemical and process industries. Scope for energy recovery is substantial, particularly from the latent heat of the exhaust moist air. Using real operating data from a major Swedish mill, optimal energy conservation strategies were investigated using different heat pump systems in paper drying. Simulation results are compared

Between 1977 and 1996, cytogenetic investigations were performed on 182 childhood (< or = 16 yr) acute lymphoblastic leukemias (ALL), constituting 94% (182 of 194) of all ALL patients diagnosed and treated at the Departments of Pediatrics, Lund and Malmo University Hospitals, Sweden, during these two decades. The cytogenetic analyses were successful in 152 cases (84%). The failure rate was higher

The recent decline of the European starling in northern Europe has been associated with changes in agricultural land-use. We investigated how agricultural land-use affected starling habitat use and home-range size in a heterogeneous landscape in southern Sweden. Breeding starlings primarily foraged in pastures, a habitat with a high availability of potential food for nestlings. When the availabili

A numerical study of the mechanical behavior of heterogeneous soil systems, consisting of a bulk of sand with embedded stiff gravel inclusions or soft clay inclusions, is performed. A solution scheme using parallel computing is employed when analyzing two different categories of problems. First, a homogenization problem is studied, where use of a single representative volume element subjected to p

The influence of a poly(styrene-graft-ethylene oxide) (P(S-g-EO)) copolymer on poly(2,6-dimethyl-p-phenylene oxide)/poly(methyl methacrylate) (PPO/PMMA) blends was studied by a number of different techniques in order to characterize the properties of the interphase. Scanning electron microscopy shows that the copolymer reduces the dispersed phase size, and dynamic mechanical spectroscopy (DMS) rev

Inhibitor of DNA binding (Id) proteins function as inhibitors of members of the basic helix-loop-helix family of transcription factors and have been demonstrated to play an important role in regulating lymphopoiesis. However, the role of these proteins in regulation of myelopoiesis is currently unclear. In this study, we have investigated the role of Id1 and Id2 in the regulation of granulopoiesis

Aim: To identify important predictors among lifestyle behaviours and physiological factors of bone mineral density (BMD) in relation to body mass index (BMI) among young women over a 2-year period. Design, sample and measurements: Data were collected in 1999 and 2001. Healthy young women (n=152) completed a questionnaire. BMD measurements were performed by DEXA in the calcaneus. The women were su