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Abstract in Italian Arthur Prior (1914-1969) si è occupato di temi che spaziano dalla logica formale all'etica, ed ha fornito contributi di grandissima importanza soprattutto nell'ambito della logica modale, della metafisica, e della filosofia del tempo. E' considerato il padre della logica temporale e il precursore della contemporanea logica ibrida, è stato un precursore della semantica a mondi p

Up-regulation of endothelin type B receptors in the human internal mammary artery in culture is dependent on protein kinase C and mitogen-activated kinase signaling pathways.

BACKGROUND: Up-regulation of vascular endothelin type B (ETB) receptors is implicated in the pathogenesis of cardiovascular disease. Culture of intact arteries has been shown to induce similar receptor alterations and has therefore been suggested as a suitable method for, ex vivo, in detail delineation of the regulation of endothelin receptors. We hypothesize that mitogen-activated kinases (MAPK)

Molecular analysis of FRIGIDA, a major determinant of natural variation in Arabidopsis flowering time

Vernalization, the acceleration of flowering by a long period of cold temperature, ensures that many plants overwinter vegetatively and flower in spring. In Arabidopsis, allelic variation at the FRIGIDA (FRI) locus is a major determinant of natural variation in flowering time. Dominant alleles of FRI confer late flowering, which is reversed to earliness by vernalization. We cloned FRI and analyzed

Det dånar uti rättens krater

Begreppen "lag" och "ordning" tycks betinga varandra. Lagen kan sägas vara garanten för ordningens upprätthållande, ett slags juridisk kodifiering av samhällets ordningsskapande föresatser. Men omvänt förutsätter lagen en ordning. Det måste finnas legitima institutioner med auktoritet att stifta och upprätthålla lagarna. Regler kan inte tillämpas på kaos, och under de senaste åren har man i debatt

Marital status and occupation in relation to short-term case fatality after a first coronary event--a population based cohort.

BACKGROUND: Although marital status and low occupation level has been associated with mortality, the relationship with case fatality rates (CFR) after a coronary event (CE) is unclear. This study explored whether incidence of CE and short-term CFR differ between groups defined in terms of marital status and occupation, and if this could be explained by biological and life-style risk factors. METHO

Establishment of heparan sulphate deficient primary endothelial cells from EXT-1(flox/flox) mouse lungs and sprouting aortas.

Angiogenesis is a hallmark of expanding tissue e.g. during embryogenesis and wound healing in physiology as well as in diseases such as cancer and atherosclerosis. Key steps of the angiogenic process involve growth factor-mediated stimulation of endothelial cell sprouting and tube formation. Heparan sulphate proteoglycans (HSPGs) have been implicated as important co-receptors of several pro-angiog

Capacitive circuit method for fast and efficient design of wideband radar absorber

A simple, fast and efficient method for designing wideband radar absorbers is proposed. The idea is to modify the circuit analog absorber method without perturbing the bandwidth. This is done by utilizing the asymptotic behavior of such an absorber at low frequency and replacing the band-stop resonating frequency selective surfaces with low-pass capacitive ones, which can be synthesized by square

Historical Archaeology in Sweden

The article outlines the early origin and later transformations of Medieval Archaeology to Historical Archaeology, both as an antiquarian practice and as an academic subject, focusing on the development in Sweden since the 17th C.

Standardization and clinical utility of thrombin-generation assays.

Thrombin generation is a key process that determines the extent of a hemostatic plug or a thrombotic process. The ensuing thrombin burst is crucial for the formation of a stable fibrin clot. During its active life, thrombin exerts a multitude of highly regulated actions on the blood and the vessel wall, including the clotting of fibrinogen. The inappropriate generation of thrombin may lead to path

The GPER1 Agonist G-1 Attenuates Endothelial Cell Proliferation by Inhibiting DNA Synthesis and Accumulating Cells in the S and G2 Phases of the Cell Cycle.

G protein-coupled receptor 30 (GPR30) or G protein-coupled estrogen receptor 1 (GPER1) is expressed in the vasculature, but the importance of vascular GPER1 remains to be clarified. Here we investigate effects of the GPER1 agonist G-1 on endothelial cell proliferation using mouse microvascular endothelial bEnd.3 cells. The bEnd.3 cells express mRNA for GPER1. The bEnd.3 cells expressed both ERα an