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A representation and classification scheme for tree-like structures in medical images : Analyzing the branching pattern of ductal trees in x-ray galactograms

We propose a multistep approach for representing and classifying tree-like structures in medical images. Tree-like structures are frequently encountered in biomedical contexts; examples are the bronchial system, the vascular topology, and the breast ductal network. We use tree encoding techniques, such as the depth-first string encoding and the Prüfer encoding, to obtain a symbolic string represen

Parenchymal Texture Analysis in Digital Breast Tomosynthesis for Breast Cancer Risk Estimation. A Preliminary Study

Rationale and Objectives: Studies have demonstrated a relationship between mammographic parenchymal texture and breast cancer risk. Although promising, texture analysis in mammograms is limited by tissue superposition. Digital breast tomosynthesis (DBT) is a novel tomographic x-ray breast imaging modality that alleviates the effect of tissue superposition, offering superior parenchymal texture vis

Mammogram registration : A phantom-based evaluation of compressed breast thickness variation effects

The temporal comparison of mammograms is complex; a wide variety of factors can cause changes in image appearance. Mammogram registration is proposed as a method to reduce the effects of these changes and potentially to emphasize genuine alterations in breast tissue. Evaluation of such registration techniques is difficult since ground truth regarding breast deformations is not available in clinica

Evaluation of a novel method of noise reduction using computer-simulated mammograms

A novel method of noise reduction has been tested for mammography using computer-simulated images for which the truth is known exactly. This method is based on comparing two images. The images are compared at different scales, using a cross-correlation function as a measure of similarity to define the image modifications in the wavelet domain. The computer-simulated images were calculated for nois

Calculation of the properties of digital mammograms using a computer simulation

A Mote Carlo computer model of mammography has been developed to study and optimise the performance of digital mammographic systems. The program uses high-resolution voxel phantoms to model the breast, which simulate the adipose and fibroglandular tissues, Cooper's ligaments, ducts and skin in three dimensions. The model calculates the dose to each tissue, and also the quantities such as energy im

Breast dosimetry using high-resolution voxel phantoms

A computer model of X-ray mammography has been developed, which uses quasi-realistic high-resolution voxel phantoms to simulate the breast. The phantoms have 400 μm voxels and simulate the three-dimensional distributions of adipose and fibroglandular tissues, Cooper's ligaments, ducts and skin and allow the estimation of dose to individual tissues. Calculations of the incident air kerma to mean gl

Mammogram synthesis using a three-dimensional simulation. III. Modeling and evaluation of the breast ductal network

A method is proposed for realistic simulation of the breast ductal network as part of a computer three-dimensional (3-D) breast phantom. The ductal network is simulated using tree models. Synthetic trees are generated based upon a description of ductal branching by ramification matrices (R matrices), whose elements represent the probabilities of branching at various levels of a tree. We simulated

Classification of galactograms with ramification matrices : Preliminary results

Rationale and Objectives. The poor specificity of galactography, the imaging modality generally indicated in cases of nipple discharge, has led to a large number of biopsies with negative results. A quantitative scheme for classifying galactographic findings might help reduce the number of such biopsies in the future. As a first step toward that goal, the authors have studied one quantitative meth

Effects of quantum noise and binocular summation on dose requirements in stereoradiography

In the case of a quantum-noise limited detector, signal detection theory suggests that stereoradiographic images can be acquired with one half of the per-image dose needed for a standard radiographic projection, as information from the two stereo images can be combined. Previously, film-screen stereoradiography has been performed using the same per-image dose as in projection radiography, i.e., do

Non-rigid registration of mammograms obtained with variable breast compression : A phantom study

The amount of breast compression applied during a mammographic exam affects the appearance of mammograms by introducing variations in the shape, position, and contrast of breast anatomical structures, which can conceal existing breast abnormalities or generate false alarms. Due to the complex tissue organization and elastic properties of the breast and the projective nature of mammography, rigid r

Aliasing effects in digital images of line-pair phantoms

Line-pair phantoms are commonly used for evaluating screen-film systems. When imaged digitally, aliasing effects give rise to additional periodic patterns. This paper examines one such effect that medical physicists are likely to encounter, and which can be used as an indicator of super-resolution.

Mammogram synthesis using a 3D simulation. I. Breast tissue model and image acquisition simulation

A method is proposed for generating synthetic mammograms based upon simulations of breast tissue and the mammographic imaging process. A computer breast model has been designed with a realistic distribution of large and medium scale tissue structures. Parameters controlling the size and placement of simulated structures (adipose compartments and ducts) provide a method for consistently modeling im

Mammogram synthesis using a 3D simulation. II. Evaluation of synthetic mammogram texture

We have evaluated a method for synthesizing mammograms by comparing the texture of clinical and synthetic mammograms. The synthesis algorithm is based upon simulations of breast tissue and the mammographic imaging process. Mammogram texture was synthesized by projections of simulated adipose tissue compartments. It was hypothesized that the synthetic and clinical texture have similar properties, a

Generation and evaluation of physically inspired synthetic mammograms

A software breast phantom, based upon a breast tissue model derived from physical properties of breast anatomy, has been developed for mammography simulation. Synthetic mammograms, obtained by applying a breast compression model and an x-ray acquisition model to the software breast phantom, were compared by quantitative and qualitative means with real mammograms at different scales. Good agreement

CNN paradigm based multilevel halftoning of digital images

-An algorithm for displaying gray level images using a small number of flxed quantization levels is proposed. The algorithm, called multilevel halftoning, is based on the Cellular Neural Networks (CNN) paradigm. It tracks the CNN transient outputs and selects the image which is subjectively perceived to be the best when reduced to the allowed number of gray levels. The selection criterion is based

Quality assurance of texture web materials using cellular neural networks

The paper present a parallel implementation of an image processing algorithm for the on-line, non-destructive quality assurance of the non-woven, fibrous web materials. The task of the algorithm is to compute the material microstructure descriptors. The premise underlying this work is that the microstructure determines the performance of the material and characterization of the microstructure may

Digital Collaborative platforms: A challenge for both the Legislator and the Social Partners in the Nordic Model

This paper focuses on the specific problems in the labour and social security legislation as it relates to crowdworkers in the digitalised new economy, analysing their place in labour market, and especially in the collective agreements which are the standard means of regulating working conditions in the Nordic model. Sweden has a binary system where a performing party is as either an employee or s

Who counts as an employer in Sweden?

In this article, the concept of the employer is analysed for Swedish conditions from a variety of perspectives. The special difficulties that face the private sector are charted, as are the principles of the legal subject in triparty contracts with temporary employment agencies, platform work, and umbrella companies. Found to go hand in hand with the concept of employee, the concept of the employe