Effects of the addition of a cationic amino acid-based synthetic amphiphile, arginine N-lauroyl amide dihydrochloride (ALA), to a lipid-based transfection formulation have been investigated. It is shown that the inclusion of ALA results in a substantial enhancement of the transfection capability of lipoplexes prepared with liposomes of 1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine and chol

This paper concerns the Cesàro operator acting on various spaces of analytic functions on the unit disc. The remarkable fact that this operator is subnormal when acting on the Hardy space H2 has lead to extensive studies of its spectral picture on other spaces of this type. We present some of the methods that have been used to obtain information about the spectrum of the Cesàro operator acting on

Background: Ectonucleotidase dependent adenosine generation has been implicated in preconditioning related cardioprotection against ischemia-reperfusion injury, and treatment with a soluble ectonucleotidase has been shown to reduce myocardial infarct size (IS) when applied prior to induction of ischemia. However, ectonucleotidase treatment according to a clinically applicable protocol, with admini

Objectives: To find variables associated with outcome following thrombolytic treatment for acute lower limb ischemia. Design: Re-analysis of a prospective multicentre study. Material and methods: One hundred and twenty-one patients with acute lower limb ischemia previously included in a randomised study comparing high- with low-dose thrombolysis were re-analysed ignoring the mode of lytic treatmen

Abstract Historical studies indicate that determinants of the gender wage gap have varied through history. This paper suggests that employment discrimination dominated over wage discrimination in clerical work in Sweden in the mid-1930s. Women were largely excluded from career paths in the offices. This is explained within an analytical framework, in which segmented labour market theory, notably c

The validity of a Swedish translation of the Measures of Criminal Attitudes and Associates (MCAA) was evaluated. All four subscales showed acceptable reliability, but the Entitlement scale can be improved by replacing items with low loadings. Confirmatory factor analysis supported a model with one common criminal attitude factor and three subfactors (corresponding to subscales of the test). The An

Background: We have developed an in vitro model by organ culture of rat mesenteric arteries to imitate vascular smooth muscle cell (VSMC) receptor changes in cardiovascular disease. By using this model, alteration of VSMC thromboxane A(2) (TP) receptors was studied. Methods and Results: After organ culture of the arteries, VSMC TP receptors were studied by using myography, real-time PCR and immuno

One option for coping with wasteful uses of fresh water in landscape irrigation is to use the treated greywater(GW). In the present study, an evaluation of a simple treatment system for reusing GW to irrigate green areas,trees, and ornamentals all over the campus in Tafila Technical University (TTU), Jordan, is presented. After 12 months of using the treatment system, the necessity for using fresh

The most common cancer treatments currently available are radio- and chemo-therapy. These therapies have, however, drawbacks, such as, the reduction in quality of life and the low efficiency of radiotherapy in cases of multiple metastases. To lessen these effects, we have encapsulated an anti-cancer drug into a biocompatible matrix. In-vitro assays indicate that this bio-nanocomposite is able to i

Previous research on human fear of large carnivores has mainly been based on self-reports in which individual survey items and the objects of fear are measured, so whether a person fears attacks on humans or livestock and pets has not been identified. The objectives of this study were to differentiate between the objects of fear as well as capturing attitudes towards implementation of management a

Single-crystal neutron diffraction reveals two distinct components to the magnetic ordering in geometrically frustrated SrEr2O4. One component is a long-range ordered k = 0 structure which appears below T-N = 0.75 K. Another component is a short-range incommensurate structure which manifests itself by the presence of a strong diffuse scattering signal. On cooling from higher temperatures down to 0

Excessive complement activation contributes to joint diseases such as rheumatoid arthritis and osteoarthritis during which cartilage proteins are fragmented and released into the synovial fluid. Some of these proteins and fragments activate complement, which may sustain inflammation. The G3 domain of large cartilage proteoglycan aggrecan interacts with other extracellular matrix proteins, fibulins

Susceptibility genes and environmental factors are important for development of Type 1 diabetes (T1D). Increased birth weight (BW), increased linear growth and gestational infections are among the reported risk factors. T1D is predictable by analysis of HLA genotypes and islet cell autoantibodies. In this thesis risk factors and prediction of T1D were studied as part of the Diabetes Prediction in

Background: Major intrinsic proteins (MIPs) also named aquaporins form channels facilitating the passive transport of water and other small polar molecules across membranes. MIPs are particularly abundant and diverse in terrestrial plants but little is known about their evolutionary history. In an attempt to investigate the origin of the plant MIP subfamilies, genomes of chlorophyte algae, the sis

A pentose-rich hydrolysate fraction obtained by extraction of steam-pretreated sugarcane bagasse was analysed with regard to dissolved phenolics. The liquid obtained after steam pretreatment (2% SO2 (w/w) at 190 ◦C for 5min)was divided into two parts: one containing dissolved compounds originating from hemicellulose (with xylose as the dominating compound), and the other containing predominantly d

FLT3 and c-KIT are crucial regulators of hematopoietic stem and progenitor cells. We investigated the role of STS1 and STS2 on FLT3 and c-KIT phosphorylation, activity, and function in normal and stress-induced hematopoiesis. STS1/STS2-deficient mice show a profound expansion of multipotent progenitor and lymphoid primed multipotent progenitor cells with elevated colony-forming capacity. Although

Popular Abstract in Swedish Sedan den industriella revolutionen har världen konfronterats med många miljöproblem, t.ex. luftföroreningar, surt regn, global uppvärmning, farligt avfall, ozonhålsproblematik, ”smog” och vattenföroreningar. Det är viktigt att utveckla mätteknik för att objektivt kunna fastställa miljöförhållandena för att sedan kunna göra adekvata åtgärder. Miljön kan direkt karakteriThis thesis studies the techniques of laser remote sensing and their applications in environmental monitoring, as documented in several published papers. The environment where the human being live is degrading with an accelerating speed. Quantitative monitoring characterizes the quality of the environment and offers possibilities to solve environmental problems. Laser remote sensing actively prob