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Dose-response analysis of protracted absorbed organ dose and site-specific cancer incidence in Sweden after the Chernobyl nuclear power plant accident

Background: Adult males in Sweden exhibit an increased risk of cancer associated with an increased absorbed dose to the colon from the Chernobyl accident. Methods: A closed cohort, with information on hunter status, included all individuals living in northern Sweden in 1986. Complete annual information on exposure to 137Cs at the dwelling coordinate was available for a total of 2,104,101 individua

Calculation of Relativistic Single-Particle States

A computational method is proposed to calculate bound and resonant states by solving the Klein–Gordon and Dirac equations for real and complex energies, respectively. The method is an extension of a non-relativistic one, where the potential is represented in a Coulomb–Sturmian basis. This basis facilitates the exact analytic evaluation of the Coulomb Green’s operator in terms of a continued fracti

Programming human cell fate : overcoming challenges and unlocking potential through technological breakthroughs

In recent years, there have been notable advancements in the ability to programme human cell identity, enabling us to design and manipulate cell function in a Petri dish. However, current protocols for generating target cell types often lack efficiency and precision, resulting in engineered cells that do not fully replicate the desired identity or functional output. This applies to different metho

Risky Sexual Behaviour and Sexual Victimization among Young People with Risky Substance Use in Europe-Perspectives from Belgium, Sweden, the Czech Republic, and Germany

BACKGROUND: Research indicates that among the risks associated with young people's alcohol and illicit drug use are sexual risks. However, insights into co-occurrence of substance use and sexual risks in adolescent samples and possible differences across countries are limited. METHODS: A sample of 1449 adolescents from Belgium, Sweden, the Czech Republic, and Germany screened positive for risky al

Galectin-3 is upregulated in frontotemporal dementia patients with subtype specificity

INTRODUCTION: Neuroinflammation is a major contributor to the progression of frontotemporal dementia (FTD). Galectin-3 (Gal-3), a microglial activation regulator, holds promise as a therapeutic target and potential biomarker. Our study aimed to investigate Gal-3 levels in patients with FTD and assess its diagnostic potential. METHODS: We examined Gal-3 levels in brain, serum, and cerebrospinal flu

A Novel Predictor for the Analysis and Prediction of Enhancers and Their Strength via Multi-View Features and Deep Forest

Enhancers are short DNA segments (50–1500 bp) that effectively activate gene transcription when transcription factors (TFs) are present. There is a correlation between the genetic differences in enhancers and numerous human disorders including cancer and inflammatory bowel disease. In computational biology, the accurate categorization of enhancers can yield important information for drug discovery

Prognostic utility and characterization of left ventricular hypertrophy using global thickness

Cardiovascular magnetic resonance (CMR) can accurately measure left ventricular (LV) mass, and several measures related to LV wall thickness exist. We hypothesized that prognosis can be used to select an optimal measure of wall thickness for characterizing LV hypertrophy. Subjects having undergone CMR were studied (cardiac patients, n = 2543; healthy volunteers, n = 100). A new measure, global wal

Alla är överens, men ingen tar ansvar? En kvalitativ undersökning om ansvar gällande långsiktiga boenden för barnfamiljer i hemlöshet

This study investigates how representatives from the Swedish Social Service and the Sweden City missions describe their responsibility concerning long-term housing for families in structural homelessness. The aim is also to have the representatives’ perspectives on how the situation for the target group can be improved. Even though the research concerning structural homelessness is well examined,

Role of FUT8 in the regulation of cellular signaling in ovarian cancer

One of the most common cancers in women Ovarian cancer is a major health issue and a leading cause of cancer-related deaths among women globally. A key factor in progression of ovarian cancer is a process called glycosylation, where sugars are added to proteins, altering their function. This process involves an enzyme named FUT8, which is crucial for adding specific sugar molecules to proteins. I

Metabolic tumour volume in Hodgkin lymphoma—A comparison between manual and AI-based analysis

Aim: To compare total metabolic tumour volume (tMTV), calculated using two artificial intelligence (AI)-based tools, with manual segmentation by specialists as the reference. Methods: Forty-eight consecutive Hodgkin lymphoma (HL) patients staged with [18F] fluorodeoxyglucose positron emission tomography/computed tomography were included. The median age was 35 years (range: 7–75), 46% female. The t

Scheduling for Industrial Control Traffic Using Massive MIMO and Large Intelligent Surfaces

Industry 4.0, with its focus on flexibility and customizability, is pushing in the direction of wireless communication in future smart factories, in particular massive multiple-input multiple-output (MIMO), and its future evolution Large Intelligent Surfaces (LIS), which provide more reliable channel quality than previous technologies. As such, there arises the need to perform efficient scheduling

Svar på kommentarer om penningpolitiken

I Ekonomisk Debatt nummer 5 2023 publicerade vi en artikel där vi studeradeorsakerna bakom kronförsvagningen mot euron (Andersson och Jonung2023). Eftersom kronan tappat i värde över en längre tid valde vi ett långsiktigt perspektiv. Här utgick vi från Cassels köpkraftsparitetsteori och visadeatt svenska priser och nominella löner stigit snabbare än i euroområdet. Kronförsvagningen är ett resultat

Clarifying and strengthening the role of law and governance in climate scenario frameworks

Shared socio-economic pathways (SSPs) and shared policy assumptions (SPAs) are lauded as a common basis for climate scenario research across disciplines, yet they lack essential legal and governance elements that are indispensable when assessing future development pathways. This article sets out to address this shortcoming by explaining the interrelated but distinct features of law and governance

Pinpointing change in virtual reality assisted treatment for violent offenders : a pilot study of Virtual Reality Aggression Prevention Training (VRAPT)

Preventing relapse into violence and its destructive consequences among persistent re-offenders is a primary concern in forensic settings. The Risk-Need-Responsivity framework models the best current practice for offender treatment, focused on building skills and changing pro-criminal cognitions. However, treatment effects are often modest, and the forensic context can obstruct the delivery of int

Genetic Predisposition to Elevated Levels of Circulating ADAM17 Is Associated with the Risk of Severe COVID-19

High levels of ADAM17 activity have emerged as an important mediator in severe COVID-19. This study aims to characterize eventual causal relationships between ADAM17 and COVID-19. Using Mendelian randomization analyses, we examined the causal effects of circulating ADAM17 on COVID-19 outcomes using summary statistics from large, genome-wide association studies of ADAM17 (up to 35,559 individuals)

DETERRENCE BY DENIAL AND RESILIENCE BUILDING

Deterrence and resilience are intimately connected. Deterrence is about understanding threats and using levers that might force an adversary to reconsider their objectives and actions against you. Resilience is about understanding yourself and the measures you can take to become a less attractive target, or to bounce back more quickly from a setback. This combination of deterrence and resilience h