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Prevalence of antibodies against Kaposi's sarcoma associated herpes virus (KSHV) complement inhibitory protein (KCP) in KSHV-related diseases and their correlation with clinical parameters.

Kaposi's sarcoma-associated herpes virus (KSHV) encodes its own inhibitor of the complement system, designated KSHV complement control protein (KCP). Previously, we detected anti-KCP antibodies in a small group of 22 patients suffering from Kaposi's sarcoma (KS) and KSHV-related lymphoproliferative diseases (Vaccine, 25:8102-9). Anti-KCP antibodies were more prevalent in individuals suffering from

Influences of space, soil, nematodes and plants on microbial community composition of chalk grassland soils

P>Microbial communities respond to a variety of environmental factors related to resources (e.g. plant and soil organic matter), habitat (e.g. soil characteristics) and predation (e.g. nematodes, protozoa and viruses). However, the relative contribution of these factors on microbial community composition is poorly understood. Here, we sampled soils from 30 chalk grassland fields located in three d

Hypoxia and cyanobacteria blooms - are they really natural features of the late Holocene history of the Baltic Sea?

During the last century (1900s) industrialized forms of agriculture and human activities have caused eutrophication of Baltic Sea waters. As a consequence, the hypoxic zone in the Baltic Sea has increased, especially during the last 50 years, and has caused severe ecosystem disturbance. Climate forcing has been proposed to be responsible for the reported trends in hypoxia (< 2 mg/l O-2) both durin

Trends in Baseline Patient Characteristics during the Years 1995-2008: Observations from Riks-Stroke, the Swedish Stroke Register

Background: Reported improvements in outcome in stroke patients treated in hospital are often attributed to advances in stroke care. However, secular trends in patient characteristics that are present already on admission to hospital may also contribute to improved outcome. Methods: Time trends for baseline data (289,854 stroke admittances) in Riks-Stroke, the Swedish national quality register for

Gastrointestinal conditions influence the solution behaviour of cereal beta-glucans in vitro

The solution behaviour of b-glucans in a gastrointestinal model was investigated in order to explore the mechanisms explaining the physiological effects of the soluble fibre. Asymmetrical flow field-flow fractionation was used to determine the molar mass distribution, and in-line calcofluor labelling allowed specific detection of b-glucans in complex samples. When dispersed in water, weight-averag

Growth hormone, prolactin and cortisol response to exercise in patients with depression

Background: A blunted growth hormone and prolactin response to pharmacological stress test have previously been found in depressed patients, as well as an increased cortisol response to psychosocial stress. This study investigated these hormones in response to acute exercise using an incremental bicycle test. Method: A cross-sectional comparison of cortisol, growth hormone, and prolactin in depres

Observations on extraction from V2 clauses in Scandinavian

Abstract in UndeterminedThis short communication presents a general overview of facts concerning wh-extraction from V2 clauses in the Scandinavian languages. While extraction from V2 clauses with a fronted non-subject is impossible in all of these languages, three classes can be distinguished with regard to extraction from subject-initial V2 clauses.

Lavage treatment of painful jaw movements at disc displacement without reduction. A randomized controlled trial in a short-term perspective.

This study compared the short-term efficacy of two treatments (local anesthetics (A) and local anesthetics and lavage (AL)) in patients with permanently displaced discs and temporomandibular disorder (TMD) pain. 45 patients participated in the single-blind randomized controlled trial. All patients had received: a Research Diagnostic Criteria/TMD diagnosis of disc displacement without reduction; an

Generalized feedforward tuning rules for non-realizable delay inversion

This paper describes the problem of load disturbance rejection using feedforward for the case when perfect compensation is not realizable due to processes delays inversion. First, a new generalized open-loop design tuning rule for feedforward compensators is proposed. Simple and intuitive guidelines are given for aggressive, moderate, and conservative performance results. Moreover, a switching fee

Alcohol use disorders are associated with venous thromboembolism.

Moderate alcohol consumption has been suggested to protect against venous thromboembolism (VTE). However, it is not known how alcohol abuse and its associated somatic complications affect the risk of VTE. The present study determined the risk of pulmonary embolism (PE) and deep vein thrombosis (DVT) of the lower extremities in patients with alcohol use disorders (AUDs) in Sweden. All inpatients wi

Analysis of the Response of AGATA Detectors at GSI

In 2012 and 2014 the γ-ray tracking spectrometer AGATA was operated at the SIS/FRS facility at GSI in Darmstadt, Germany. The performance of the array is discussed, outlining some important aspects of the offline data processing and analysis. Relying on the data obtained from measurements with standard γ-ray sources, a first estimate of the photopeak efficiency and peak-to-total (P/T) is presented

The activity of rot fungi (Postia placenta) during drying and rewetting cycles measured by isothermal calorimetry

Rot fungi are a major problem in the construction sector, and method to study under which moisture and temperature coefficients they grow are therefore of significant interest. Measurements of heat production rate have been made on wood samples with the brown rot fungus Postia placenta at different moisture contents (MCs). The results clearly show the heat production rate (a measure of respiration

The Cedell method (cerclage wire and staple) leads to less reoperations than the AO method.

Background and purpose - Fractures of the lateral malleolus often require open reduction and internal fixation (ORIF). Despite uneventful fracture healing, many patients will suffer from long-term detriments after ORIF, such as local tenderness that requires hardware removal. In Sweden, there are 2 major fixation methods, either the AO method (plate and screws) or the Cedell method (cerclage wire

Recurrent PRDM10 Gene Fusions in Undifferentiated Pleomorphic Sarcoma.

Purpose: Undifferentiated pleomorphic sarcoma (UPS) is defined as a sarcoma with cellular pleomorphism and no identifiable line of differentiation. It is typically a high-grade lesion with a metastatic rate of about 1/3. No tumor-specific rearrangement has been identified and genetic markers that could be used for treatment stratification are lacking. We performed transcriptome sequencing (RNA-Seq

Effect of heat tretment and homogenization on the rheological properties of aqueous parsnip suspensions

Parsnip (Pastinaca sativa) suspensions, at concentrations corresponding to a dilute and concentrated regime, were subjected to pasteurization, and heat treatments that favored beta-elimination reactions and pectin methyl esterase activity. The different heat treatments were combined with homogenization. Physicochemical properties such as content of insoluble/soluble material and insoluble/soluble

Extended structure tensors for multiple directionality estimation

Standard structure tensors provide a robust way of directionality estimation of waves (or edges) but only for the case when they do not intersect. In this work, a structure tensor extension using a one-way wave equation is proposed as a tool for estimating directionality in seismic data and images in the presence of conflicting dips. Detection of two intersecting waves is possible in a two-dimensi

Soluble amyloid precursor protein alpha and beta in CSF in Alzheimer's disease

Objective: Cerebral accumulation of amyloid beta (A beta) is a pathological hallmark of Alzheimer's disease (AD). Proteolytic processing of amyloid precursor protein (APP) by alpha- or beta-secretase results in two soluble metabolites, sAPP alpha and sAPP beta, respectively. However, previous data have shown that both alpha- and beta-secretase have multiple cleavage sites. The aim of this study wa

Pharmaceuticals and personal care products (PPCPs) in treated wastewater discharges into Charleston Harbor, South Carolina

This study assessed seasonal and regional trends of pharmaceuticals and personal care products (PPCPs) detected in monthly samples from two local wastewater treatment plants (WWTPs) in Charleston, South Carolina, USA, over the period of one year. Surface water of Charleston Harbor was also analyzed to examine environmental distribution in an estuarine ecosystem. Of the 19 compounds examined, 11 we

Mathematical modeling and statistical analysis of calcium-regulated insulin granule exocytosis in beta-cells from mice and humans.

Insulin is released from pancreatic beta-cells as a result of Ca(2+)-evoked exocytosis of dense-core granules. Secretion is biphasic, which has been suggested to correspond to the release of different granule pools. Here we review and carefully reanalyze previously published patch-clamp data on depolarization-evoked Ca(2+)-currents and corresponding capacitance measurements. Using a statistical mi