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Risk of pulmonary embolism and deep venous thrombosis in patients with asthma : A nationwide case-control study from Sweden

Asthma is associated with an increased risk of pulmonary embolism (PE) but little is known about whether asthma is associated with an increased risk of deep venous thrombosis (DVT). The aim in this study was to determine the risk of the first event of PE, DVT or a combination of PE and DVT in patients with asthma. We conducted this nationwide case-control study using data from Swedish nationwide r

Clinical Correlates of Benefit From Radium-223 Therapy in Metastatic Castration Resistant Prostate Cancer

BACKGROUND: We sought to identify potential clinical variables associated with outcomes after radium-223 therapy in routine practice. METHODS: Consecutive non-trial mCRPC patients who received ≥1 dose of radium dichloride-223 at four academic and one community urology-specific cancer centers from May 2013 to June 2014 were retrospectively identified. Association of baseline and on-therapy clinical

Rare and low-frequency coding variants alter human adult height

Height is a highly heritable, classic polygenic trait with approximately 700 common associated variants identified through genome-wide association studies so far. Here, we report 83 height-associated coding variants with lower minor-allele frequencies (in the range of 0.1-4.8%) and effects of up to 2 centimetres per allele (such as those in IHH, STC2, AR and CRISPLD2), greater than ten times the a

Two-Dimensional Platform for Networks of Majorana Bound States

We model theoretically a two-dimensional electron gas (2DEG) covered by a superconductor and demonstrate that topological superconducting channels are formed when stripes of the superconducting layer are removed. As a consequence, Majorana bound states (MBSs) are created at the ends of the stripes. We calculate the topological invariant and energy gap of a single stripe, using realistic values for

A healthier US diet could reduce greenhouse gas emissions from both the food and health care systems

The standard US diet contributes to greenhouse gas emissions (GHGE) from both the food system, and from the health system through its contribution to non-communicable diseases. To estimate the potential for diet change to reduce GHGE and improve public health, we analyzed the effect of adopting healthier model diets in the USA on the risk of disease, health care costs, and GHGE. We found that adop

Development of the gastrointestinal tract in young mammals : Effects of enteral provocation with protease or phytohaemagglutinin in neonatal rats

Råttan är en däggdjursart med en kort dräktighetstiden och föds därför mycket omogen. Den är vid födelsen naken, blind och döv och är helt beroende av sin moder för många funktioner, såsom näringstillförsel, termoreglering, urinering och tarmtömning. Under diperioden är råttans mag-tarmsystem och matsmältning helt anpassad till modersmjölkdieten. Bland annat är tarmens barriärfunktion omogen, vilkThe rat, as an altritial species, is born with an immature gastrointestinal tract and intestinal barrier function, which is highly absorptive to milk-borne bioactive molecules that can pass undigested and reach the general circulation of the suckling newborn. This passage occurs by the neonatal-Fc-receptor (FcRn) binding and trancytosis of immunoglobulin G in the proximal small intestine (SI) and

An analytical method for calculating the thermal conductivity of a twin pipe in district heating system

In this paper a simple analytical method is introduced for calculating the overall thermal conductivity of a twin pipe in district heating network. The method is developed based on calculating the conductive and convective heat transfer around the casing pipe in different perimetral sections. Temperature inside the supply and return pipes and also over the heating pipe is measured on different poi

Conceptual design of the AGATA 1π array at GANIL

The Advanced GAmma Tracking Array (AGATA) has been installed at the GANIL facility, Caen-France. This set-up exploits the stable and radioactive heavy-ions beams delivered by the cyclotron accelerator complex of GANIL. Additionally, it benefits from a large palette of ancillary detectors and spectrometers to address in-beam γ-ray spectroscopy of exotic nuclei. The set-up has been designed to coupl

Earth's oldest 'Bobbit worm' - Gigantism in a Devonian eunicidan polychaete

Whilst the fossil record of polychaete worms extends to the early Cambrian, much data on this group derive from microfossils known as scolecodonts. These are sclerotized jaw elements, which generally range from 0.1-2 mm in size, and which, in contrast to the soft-body anatomy, have good preservation potential and a continuous fossil record. Here we describe a new eunicidan polychaete, Websteroprio

Censored Multipath Component Cross-Polarization Ratio Modeling

In wireless channel measurements, the relatively weak cross-polarized multipath components (MPCs) are typically severely affected by the measurement noise level. As shown in this letter, the typical cross-polarization ratio (XPR) model parameter estimation, which ignores the existence of censored samples, may lead to significant errors. We demonstrate how to achieve accurate parameter estimates wi

High prevalence of Leucocytozoon parasites in fresh water breeding gulls

Seabirds are regarded as a group of species with relatively low levels or even complete lack of blood parasites. We used PCR to amplify a DNA fragment from the cytochrome b gene of the parasites to search for infections of the genera Plasmodium, Haemoproteus and Leucocytozoon in individuals of two sympatrically breeding gull species, the Herring Gull Larus argentatus, the Caspian Gull Larus cachin

Policies to support reconditioning and reuse of ICT

Circular business models are considered to be one of the key building blocks in the transition to a Circular Economy, but the viability of such business models is often dependent upon supporting policies. Relevant policies include support for waste infrastructure, regulatory frameworks, taxes and charges, and various informative instruments. This contribution reviews the literature on circular eco

Homography-Based Positioning and Planar Motion Recovery

Planar motion is an important and frequently occurring situation in mobile robotics applications. This thesis concerns estimation of ego-motion and pose of a single downwards oriented camera under the assumptions of planar motion and known internal camera parameters. The so called essential matrix (or its uncalibrated counterpart, the fundamental matrix) is frequently used in computer vision appli

Explosive ice multiplication induced by multiplicative-noise fluctuation of mechanical breakup in ice-ice collisions

The number of ice fragments generated by breakup of large graupel in collisions with small graupel fluctuates randomly owing to fluctuations in relative sizes and densities of colliding graupel particles and the stochastic nature of fracture propagation. This paper investigates the impact of the stochasticity of breakup on ice multiplication. When both the rate of generation of primary ice and the