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Associations between APOE Genotypes and Disease Susceptibility, Joint Damage and Lipid Levels in Patients with Rheumatoid Arthritis

Objective: Apolipoprotein E (APOE) genotypes are associated with cardiovascular disease (CVD) and lipid levels. In rheumatoid arthritis (RA), an association has been found with disease activity. We examined the associations between APOE genotypes and disease susceptibility and markers of disease severity in RA, including radiographic joint damage, inflammatory markers, lipid levels and cardiovascu

Phase Behavior of Microemulsions Formulated with Sodium Alkyl Polypropylene Oxide Sulfate and a Cationic Hydrotrope

The partial ternary phase diagram of anionic extended surfactant of alkyl polypropylene oxide sulfate C-12(PO)(4)SO4 alone and combined with the cationic hydrotrope, tetrabutyl ammonium bromide with water and decane were determined under ambient conditions. Middle phase microemulsion was formulated using salinity scans in the dilute region of surfactant/brine/decane. Visual inspection as well as c

Galerkin-based mechanical integrators for finite elastodynamics formulated in principal stretches - pitfalls and remedies

In the present paper we deal with integrators relying on Finite Elements in time for general hyperelastic models which guarantee the conservation of the momentum maps as well as of the total energy within the calculation accuracy. In the isotropic case, eigenvalue-based constitutive laws are, on the one hand, very significant to model the behaviour of various materials. On the other hand, it will

High risk of tobacco-related cancers in CDKN2A mutation-positive melanoma families.

Germline mutations in the tumour suppressor gene CDKN2A occur in 5-20% of familial melanoma cases. A single founder mutation, p.Arg112dup, accounts for the majority of CDKN2A mutations in Swedish carriers. In a national program, carriers of p.Arg112dup mutation have been identified. The aim of this study was to assess cancer risks in p.Arg112dup carriers and their first degree relatives (FDRs) and

The impact of autonomic dysfunction on survival in patients with dementia with lewy bodies and Parkinson's disease with dementia.

Autonomic dysfunction is a well-known feature in neurodegenerative dementias, especially common in α-synucleinopathies like dementia with Lewy bodies and Parkinson's disease with dementia. The most common symptoms are orthostatic hypotension, incontinence and constipation, but its relevance in clinical practice is poorly understood. There are no earlier studies addressing the influence of autonomi

Interactive influence of light intensity and soil fertility on root-associated arbuscular mycorrhizal fungi

Soil nutrients and light have major effects on the economics of arbuscular mycorrhizal (AM) symbioses. This study tests the main and interactive effects of soil fertility and light on AM fungal community. We conducted a 3 year mesocosm experiment with a full two factorial design: light (full light or shade) and soil fertility (unfertilized or fertilized), on the Qinghai-Tibetan Plateau. Plant trai

Development and the documentation of indigenous knowledge: Good intentions in bad company?

There appears to be an increasing interest within library and information studies (LIS) in so-called indigenous or traditional knowledge. Discussions on usefulness and applicability of indigenous knowledge in development seem to be motivating electronic documentation and the creation of databases. Often, definitions provided by international organisations are drawn on unquestioningly, while power

beta -Delayed gamma -Ray Spectroscopy of Heavy Neutron Rich Nuclei "South" of Lead

Relativistic projectile fragmentation of a Pb-208 primary beam has been used to produce neutron-rich nuclei with proton-holes relative to the Z = 82 shell closure, i.e., "south" of Pb. beta-delayed gamma-ray spectroscopy allows to investigate the structural properties of such nuclei with A similar to 195 -> 205. The current work presents transitions de-exciting excited states in Au-204, which are

Extending the Intermediate Data Structure (IDS) for longitudinal historical databases to include geographic data

The Intermediate Data Structure (IDS) is a standardised database structure for longitudinal historical databases. Such a common structure facilitates data sharing and comparative research. In this study, we propose an extended version of IDS, named IDS-Geo, that also includes geographic data. The geographic data that will be stored in IDS-Geo are primarily buildings and/or property units, and the

Adsorbate induced surface alloy formation investigated by near ambient pressure X-ray photoelectron spectroscopy

Formation of meta-stable surface-alloys can be used as a way to tune the binding strength of reaction intermediates and could therefore be used as improved catalyst materials for heterogeneous catalysis. Understanding the role of adsorbates on such alloy surfaces can provide new insights for engineering of more active or selective catalyst materials. Dynamical surface changes on alloy surfaces due

Ecosystem impacts of hypoxia: thresholds of hypoxia and pathways to recovery

Coastal hypoxia is increasing in the global coastal zone, where it is recognized as a major threat to biota. Managerial efforts to prevent hypoxia and achieve recovery of ecosystems already affected by hypoxia are largely based on nutrient reduction plans. However, these managerial efforts need to be informed by predictions on the thresholds of hypoxia (i.e. the oxygen levels required to conserve

Analyzing an automotive testing process with evidence-based software engineering

Context: Evidence-based software engineering (EBSE) provides a process for solving practical problems based on a rigorous research approach. The primary focus so far was on mapping and aggregating evidence through systematic reviews. Objectives: We extend existing work on evidence-based software engineering by using the EBSE process in an industrial case to help an organization to improve its auto

Sodium and potassium monolayers on Be(0001) investigated by photoemission and electronic structure calculations

Photoemission spectra show that Be(0001) surface states shift to lower energy with increasing Na or K coverage in the monolayer range. At an intermediate monolayer coverage a quantum well state appears near the Fermi edge and shifts to lower energy reaching saturation energy at full monolayer coverage. At full monolayer coverage low energy electron diffraction shows 2 X 2 order for K while Na form

Problemet är att lagarna inte efterlevs

Det kinesiska samhället har blivit alltmer baserat på lag och rätt. Men tyvärr efterlevs inte lagarna. Kommunistpartiets maktmonopol är inte enda hindret för att implementera lagar. Med i bilden finns också svaga institutioner, oklara maktbefogenheter, korruption och bristande kunskaper i rättsfrågor. Den snabba ekonomiska utvecklingen har exempelvis lett till att lokalregeringar ser mellan fingra