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Using laser-Doppler flowmetry during ventriculocisternal perfusion with inulin-[14C]carboxylic acid, choroid plexus blood flow (CPBF) and CSF production were measured simultaneously in rats during periods of 3 h. Blood flow and CSF production decreased only slightly during control experiments. The effect of vasoactive intestinal polypeptide (VIP) was studied at different concentrations of the pept

A well-known effect of increasing age is the gradual reduction of muscle function, and thus of performance in the activity of daily living. Recent research has shown that, even among the very elderly, exercise can improve not only strength and endurance, but also balance and mobility, thus reducing the risk of falls. The possibility of counteracting some of the age-related muscle changes has also

Problemen med alkali-kiselsyrareaktioner i Sverige ('AKRIS') är nya och började uppträda då ett cement med högre alkalihalt ersatte det tidigare lågalkalicementet som använts i södra Skåne, där betonggrus normalt innehåller alkalireaktiva korn av opalflinta och opalsandsten.Bara på 'fuktiga inomhuskonsruktioner', som har haft en speciell fukthistoria, har pop-outs uppkommit.

A comparison between the effect of low molecular weight heparin (LMWH) and unfragmented heparin (UH) on induction of osteoporosis was made in 60 rats treated with either UH (2 IU/g bw), LMWH in 2 doses (2 XaI U/g or 0.4 XaI U/g) or placebo (saline) for 34 days. Studied variables were: bone mineral mass in femora; fragility of humera; zinc and calcium levels in serum and bone ash and albumin in pla

Altered renal function is an essential component of the pathophysiological process in preeclampsia. The kidneys play a significant part in the turnover of most low molecular weight substances such as creatinine, urate and cystatin C. The present work was undertaken to investigate if the serum levels of these components are altered in characteristic ways in preeclampsia, and can be used to assist i

Culture is undoubtedly one of the most significant aspects of identity, yet our understanding of the concept and particularly of its consequences for international conflict management is underdeveloped. In this article, we test the hypothesis that cultural differences between parties reflect diversity and contradictions, and that these differences compound the difficulties faced by conflicting par

Infection and inflammation are characterized by the release of chemotactic substances that activate cells of the immune system. One of these important mediators is LTB4, an arachidonic acid derivate that attracts e.g. monocytes and granulocytes to inflammatory sites and induces phagocytosis and degranulation. LTB4 binds to BLT1 which is a 7-transmembrane receptor that belongs to the superfamily of

In vision-based feedback control systems, the time to obtain sensor information is usually non-negligible, and these systems thereby possess fundamentally different timing behavior compared to standard real-time control applications. For many image-based tracking algorithms, however, it is possible to trade-off the computational time versus the accuracy of the produced position/orientation estimat

Apolipoprotein M (apoM) is a novel apolipoprotein presented mostly in high-density lipoprotein (HDL) in human plasma, and is exclusively expressed in liver and in kidney. The pathophysiological function of apoM has not yet been elucidated. Apolipoprotein B (apoB), the characteristic apolipoprotein of low-density lipoprotein (LDL), is like apoM, a very hydrophobic protein, and thereafter they both

Popular Abstract in Swedish Sedering vid respiratorbehandling inom intensivvård ? praxis av sedering och patienters minnen, påfrestande upplevelser och psykologiska problem Akut svårt sjuka patienter i behov av respiratorbehandling på en intensivvårds-avdelning (IVA) utsätts för akut stress och diverse obehag från sjukdomen och/eller skadan, behandlingen, andningstuben och IVA-miljön. MinnesstörnThe overall aim of this thesis was to describe and determine intensive care sedation in adult mechanically ventilated patients with the emphasis on patients? memory, stressful experiences and psychological distress. The results are based on a nationwide postal survey (Paper I) including 89 Swedish intensive care units (ICUs) followed by a prospective cohort study (Papers II?IV) conducted over 18 m

Popular Abstract in Swedish Bröstcancer är den vanligast förekommande cancerformen hos kvinnor och årligen drabbas ungefär 6000 kvinnor i Sverige. I de flesta fall uppstår bröstcancer spontant, men viss ärftlighet ligger bakom ca 10 % fallen. Det finns kopplingar till faktorer som ökar risken för bröstcancer. Till riskfaktorer hör bl.a. långvarig exponering för hormoner: tidig mens och sent klimakUnrestrained proliferation is a hallmark of cancer and genetic defects within G1/S-phase regulation and the pRb pathway occur frequently. Proliferation control can be circumvented either by excess cyclin D1 or cyclin E, alterations that can define two alternative tumour biologic pathways in breast cancer. By overexpressing cyclin E in a cell line model system we demonstrate that the capacity of ce