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High variability in stem cell research is a well-known limiting phenomenon, with technical variation across experiments and laboratories often surpassing variation caused by genotypic effects of induced pluripotent stem cell (iPSC) lines. Evaluation of kidney organoid protocols and culture conditions across laboratories remains scarce in the literature. We used the original air-medium interface pr
Sufficiently strong and long-lasting first-order phase transitions can produce primordial black holes (PBHs) that contribute substantially to the dark matter abundance of the Universe, and can produce large-scale primordial magnetic fields. We study these mechanisms in a generic class of conformal U(1)'models that also explain active neutrino oscillation data via the type-I seesaw mechanism. We fi
Dynamisk motorisk talbedömning, DYMTA, är ett test som används för bedömning av talstörning, särskilt vid misstanke om motoriska talsvårigheter. DYMTAs dynamiska testmetod innebär att logopeden ger stöd och ledtrådar under bedömningen för att få en uppfattning om individens maximala förmåga. Yttre tecken ger information som kan härledas till grundorsaker, tex talplaneringssvårigheter.
The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) have collaborated to produce these post-resuscitation care guidelines for adults, which are based on the International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations (CoSTR) pubished by the International Liaison Committee on Resuscitation (ILCOR). The topics cover
These European Resuscitation Council Guidelines 2025 on epidemiology of resuscitation provides key information about incidence, patients’ characteristics, system organisation and outcomes for both out-of-hospital and in-hospital cardiac arrest in Europe and beyond. Information regarding patients’ post survival experience and causes of cardiac arrest, including genetic factors, are also reported. R
Adaptive network dynamical systems describe the co-evolution of dynamical quantities on the nodes and the dynamics of the network connections themselves. For dense networks of many nodes, the resulting dynamics are typically high-dimensional. Here, we consider adaptive dynamical systems subject to constraints on network adaptation: Asymptotically, the adaptive dynamics of network connections evolv
Understanding the dynamics of post-fire carbon recovery is critical for managing boreal forests under climate change. This study evaluates the LPJ-GUESS-BLAZE models’ performance in simulating vegetation structure, fire emissions, and post-fire carbon dynamics at the stand scale in a boreal forest in Sweden. Combining current climate and future scenarios (SSP1–2.6, SSP5–8.5), we investigated the i
Resilience is a critical issue for water resource systems. Over the past few decades, these systems have been significantly disrupted by natural disasters and human activities, resulting in substantial economic losses. This study develops a resilience evaluation framework based on a comprehensive literature review and applies it to assess the resilience of the Yangtze River Basin (YRB). The result
Eddy covariance measurement of species that are co-emitted with carbon dioxide (CO2), such as carbon monoxide (CO) and nitrogen oxides NO and NO2 (NOx), provides an opportunity to attribute a net flux to individual source or sink categories. We present eight months of continuous simultaneous measurements of fluxes (F) of CO2, CO, NOx, methane (CH4), and nitrous oxide (N2O) from a tall tower (112 m
Diabetic kidney disease (DKD) is a health burden that lacks specific and early diagnostic biomarkers. For their discovery, we sequenced urinary extracellular vesicle miRNAs in a type 1 diabetes cohort of males with and without DKD. The results were replicated by sequencing or qPCR in two independent cohorts and six published datasets, including type 1 and 2 diabetes, and both sexes. We also valida
Introduction: Fatigue is a troublesome symptom after heart transplantation and is poorly studied in a long-term perspective. One hypothesis is that there is a strong relationship between fatigue, sleep problems, and self-efficacy, and that fatigue decreases self-efficacy. The aim of this study was to explore self-reported fatigue from the time on the waiting list to 5 years after heart transplanta
Thirteenth-century interpreters of Aristotle’s Topics put forward metaphysical accounts aiming to underpin Aristotle’s account of dialectical argumentation. The reason for this, I surmise, is that they took Aristotelian logic to be a scientific method, a crucial part of which is the dialectical method provided in the Topics. Dialectical arguments proceed distinctively from acceptable premises whic
We show how the endowment effect can be interpreted in terms of ambiguity aversion. Agents take status quo as their reference point, relative to which they evaluate potential trades. The value of exchanged goods is ambiguous, represented by a set of probability distributions over possible values. Agents are ambiguity averse, modeled as maxmin expected utility maximisers. This characteristic leads
Climate change calls for adaptive strategies to manage land system across governance levels, as differing multi-level policies distinctly shape land system and long-term ecosystem resilience. This study proposes an iterative approach for optimizing land-use pathways that balance competing policy objectives across national, provincial, and local levels without compromising ecosystem integrity in a
Background: Endocrine science remains underrepresented in European Union research programmes despite the fundamental role of hormone health in human wellbeing. Analysis of the CORDIS database reveals a persistent gap between the societal impact of endocrine disorders and their research prioritisation. At national funding level, endocrine societies report limited or little attention of national res
