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On the scope and assessment of pesticides in groundwater in Skåne, Sweden

Popular Abstract in Swedish Grundvatten, det vatten som förekommer i hålrum i underjorden, är en av våra allra viktigaste naturresurser. Grundvattnet utgör den absolut största andelen för oss tillgängligt färskvatten och används för att producera mat och som processvatten inom olika industrier. Ungefär hälften av jordens dricksvattenförsörjning baseras på grundvattenuttag och ekosystem världen övePesticides are known to occur in groundwater worldwide. However, long-term pollution concerns and cause-effect relationships for specific regions remain limited. This thesis explores the occurrence of pesticides in south-Swedish groundwater, with the aims of providing a better knowledge basis for assessment and management of present-day and future pollution risks. The investigations are restricted

Befolkning, samhälle och förändring : Dynamik i Halmstad under fyra decennier

Popular Abstract in Swedish Förändringar i samhället diskuteras ofta på en aggregerad nivå där det argumenteras för att samhället förändras från ett modernt industrisamhälle till ett postindustriellt samhälle. Genom att studera samhället på en lokal nivå är det möjligt att studera komplexitet och variationer av de aggregerade teorierna kring samhällsförändring, det vill säga studera förändring i eChanges in society are often discussed on an aggregated level and it is argued that society is changing from a modern industrial society to a post-industrial society. Through studying changes on a local level it is possible to study the complexity and variations of the general and aggregated theories of societal changes, and place changes in a context of time and place. The main object of this stu

Stressful Life Events and the Metabolic Syndrome - The Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia Study

OBJECTIVE - Stress may play a role in the pathogenesis of the metabolic syndrome. However, the scant evidence available is not population-based, restricting the external validity of the findings. Our aim was to test associations between stressful life events, their accumulation, and the metabolic syndrome in a large population-based cohort. We also tested associations between stress and the indivi

Thermodynamically based fictitious crack/interface model for general normal and shear loading

For small deformations a crack/interface model that considers general 3D normal and shear loading is proposed. It involves elasticity, plasticity and damage and it is thermodynamically based. An essential feature of the model is its consistency with the concepts behind the fictitious crack model. In particular, no crack deformation occurs before the crack is initiated and when a crack has just bee

Vacuum-Assisted Closure Therapy after Cardiac Surgery. Sternal Stability, Cost of Care, Learning Curve and Hemodynamic Outcome

Deep sternal wound infection (DSWI) following cardiothoracic surgery is a rare but potentially life-threatening complication with high morbidity and mortality. DSWI is associated with a significant increase in the length of hospital stay and the cost of hospitalization. The socioeconomic impact of DSWI is considerable. Conventional treatment includes reexploration, surgical debridement, mediastin

HOST EPIGENETIC REGULATOR BMI1 AND VIRAL FIBER PROTEIN FOR EQUILIBRIUM BETWEEN ADENOVIRUS AND HOST

Popular Abstract in Swedish Adenovirus från människa (Ad) används ofta vid genterapi mot cancer, vaccinutveckling och genöverföring. Modifierade Ad5 och Ad2 virus har framgångsrikt använts som cancercelldödande (onkolytiska) agens i experimentella studier som dock inte kunnat överföras till kliniskt bruk av flera skäl, inklusive bristande spridning av virusinfektionen inom tumörvävnaden. De onkolyHuman adenoviruses (Ads) are broadly used in cancer gene therapy, vaccine development and gene delivery. The modified Ad5 or Ad2 viruses have been successfully used as oncolytic agents in pre-clinical studies. However they could not be translated into clinic utility due to a number of limitations including inefficient Ad spread among tumor cells. The cancer cell killing capacity of oncolytic Ad is

Role of NFAT (nuclear factor of activated T cells) in vascular smooth muscle

The calcium-dependent transcription factor NFAT was first described as a key player in immune cell regulation. Since then, NFAT signaling has been shown to be crucial for normal vascular development during embryogenesis. This pathway is also an important regulator of cell growth and differentiation in various cell types, however, the functional significance of NFAT in the vasculature is largely un

Lavfloran i Lunds stadspark

Även parker kan vara tämligen artrika och hysa rödlistade arter. Nedan redovisar Ulf Arup resultatet av en inventering av Lunds stadspark, som trots att den är omgiven av vägar med delvis stark trafik uppvisar en god artrikedom.

Drug survival on TNF inhibitors in patients with rheumatoid arthritis comparison of adalimumab, etanercept and infliximab

Objective To compare drug survival on adalimumab, etanercept and infliximab in patients with rheumatoid arthritis (RA). Methods Patients with RA (n=9139; 76% women; mean age 56 years) starting their first tumour necrosis factor (TNF) inhibitor between 2003 and 2011 were identified in the Swedish Biologics Register (ARTIS). Data were collected through 31 December 2011. Drug survival over up to 5 ye

Effects of cyanobacteria on fitness components of the herbivore Daphnia

Cyanobacteria are known to negatively affect their herbivores either by being of low nutritional value, by clogging the feeding apparatus or by producing toxins, and specifically, the role of toxins has been debated. Hence, in order to assess to what extent cyanobacterial toxins affect a major herbivore (Daphnia magna) that has had previous experience of cyanobacterial toxins, we conducted a life-

Migration Patterns in Duhok Governorate, Iraq, 2000-2010

Migration is commonly associated with large scale movements of people, from one country to another, both in terms of refugee displacement and voluntary migration. The internal movement within countries is however less studied despite the fact that this is an important indicator for imbalance and also crucial for planning the future for the country. In Iraq, a major reason for migration has been se

The fibrinogen cleavage product A alpha-Val(360), a specific marker of neutrophil elastase activity in vivo

Background Alpha-1-antitrypsin (A1AT) deficiency is the only recognised genetic risk factor for chronic obstructive pulmonary disease (COPD), a leading cause of morbidity and mortality worldwide. Since A1AT is the major inhibitor of neutrophil elastase (NE), this enzyme has become widely implicated in the pathogenesis of COPD in general; however, there is currently no specific biomarker for its pr

Optimal Nonparametric Covariance Function Estimation for Any Family of Nonstationary Random Processes

A covariance function estimate of a zero-mean nonstationary random process in discrete time is accomplished from one observed realization by weighting observations with a kernel function. Several kernel functions have been proposed in the literature. In this paper, we prove that the mean square error (MSE) optimal kernel function for any parameterized family of random processes can be computed as

Improving photo-stability of conjugated polymer MEH-PPV embedded in solid matrices by purification of the matrix polymer

For single molecule spectroscopy (SMS), molecules under study are usually immobilized in a polymer matrix e. g. poly(methyl methacrylate). We show a very significant improvement of the conjugated polymer MEH-PPV photo-stability and decrease of the luminescence impurities concentration when the matrix is purified. We identify benzoyl peroxide (a common radical initiator) as a possible oxidizing age