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The Öresund region as a destination : A reflection from an insider
Fungerar entreprenörskapsutbildning på universitetsnivå? Ett balanserat lärande för att utveckla kunskaper att företa sig entreprenöriella karriärer
I kapitel 4 utforskar Gustav Hägg hur väl entreprenörskapsutbildningar fung- erar och varför vi överhuvudtaget ska satsa på utbildning i entreprenörskap. Kapitelförfattaren lyfter inledningsvis att entreprenören ofta associeras med enhör- ningen och att det inte sällan är framgångsrika individer som lyfts fram. Enligt Hägg är detta missvisande då entreprenören kommer i alla möjliga skepnader och fI kapitel 4 utforskar Gustav Hägg hur väl entreprenörskapsutbildningar fung- erar och varför vi överhuvudtaget ska satsa på utbildning i entreprenörskap. Kapitelförfattaren lyfter inledningsvis att entreprenören ofta associeras med enhör- ningen och att det inte sällan är framgångsrika individer som lyfts fram. Enligt Hägg är detta missvisande då entreprenören kommer i alla möjliga skepnader och f
Tauopathy-Associated Tau Fragment Ending at Amino Acid 224 Is Generated by Calpain-2 Cleavage
BACKGROUND: Tau aggregation in neurons and glial cells characterizes tauopathies as Alzheimer's disease (AD), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD). Tau proteolysis has been proposed as a trigger for tau aggregation and tau fragments have been observed in brain and cerebrospinal fluid (CSF). Our group identified a major tau cleavage at amino acid (aa) 224 in CSF
Fynden i centrum : Keramik, glas och metall från Uppåkra
Dronedarone treatment following cardioversion in patients with atrial fibrillation/flutter : A post hoc analysis of the EURIDIS and ADONIS trials
Introduction: The phase 3 EURIDIS and ADONIS studies evaluated dronedarone for atrial fibrillation (AF)/atrial flutter (AFL) recurrence in patients with nonpermanent AF. Here we assessed whether patient characteristics and/or treatment outcomes in these studies differed based on the need for cardioversion before randomization. Methods: Time to adjudicated first AF/AFL recurrence, symptomatic recur
Studies of gas-particle interaction : Implications for the streaming instability in protoplanetary disks
We present the early results from a novel experiment to study a particle-laden flow, under a parameter regime relevant to the conditions in planet-forming systems. We investigate the gas-particle interactions to identify the presence of and details regarding the streaming instability, which is theoretically predicted to aid the coalescence of small dust grains to form planetesimals - the macroscop
Expression of the CGRP Family of Neuropeptides and their Receptors in the Trigeminal Ganglion
The calcitonin gene-related peptide (CGRP) family of neuropeptides, consists of CGRP, adrenomedullin, amylin, and calcitonin. The receptors consist of either calcitonin receptor-like receptor (CLR) or calcitonin receptor (CTR) which for function needs an accessory protein, receptor activity-modifying proteins (RAMPs). CGRP has a pivotal role in primary headaches but the role of the other members o
Fermentation of Cauliflower and White Beans with Lactobacillus plantarum – Impact on Levels of Riboflavin, Folate, Vitamin B12, and Amino Acid Composition
As diets change in response to ethical, environmental, and health concerns surrounding meat consumption, fermentation has potential to improve the taste and nutritional qualities of plant-based foods. In this study, cauliflower, white beans, and a 50:50 cauliflower-white bean mixture were fermented using different strains of Lactobacillus plantarum. In all treatments containing cauliflower, the pH
Multimeric fusion single-chain variable fragments as potential novel high-capacity ligands
In basic and applied biotechnology, design of affinity ligands has become essential for high-capacity applications such as affinity-based downstream processes for therapeutic molecules. Here, we established a proof-of-concept for the use of multimeric fusion single-chain variable fragment (scFvs) as high-capacity ligands in affinity adsorbents. Mono- and di/tri-scFvs separated by Pro-rich negative
The properties of α-synuclein secondary nuclei are dominated by the solution conditions rather than the seed fibril strain
Amyloid fibrils of α-synuclein (α-syn) are a component of Lewy bodies, the characteristic hallmark of Parkinson's disease. Amyloid fibrils arise through primary nucleation from monomers, which in the case of α-syn is often heterogeneous, followed by the growth of the nuclei by monomer addition. Secondary nucleation corresponds to the formation of new fibrils facilitated by pre-existing fibrils. Wh
Pelvic sentinel lymph node biopsy in endometrial cancer- A simplified algorithm based on histology and lymphatic anatomy
Objective: To achieve the full potential of sentinel lymph node (SLN) detection in endometrial cancer, both presumed low- A nd high-risk groups should be included. Perioperative resource use and complications should be minimized. Knowledge on distribution and common anatomical sites for metastatic SLNs may contribute to optimizing the concept while maintaining sensitivity. Proceeding from previous
Investment shocks and inequality dynamics
We explore the dynamics of income and income inequality under asymmetric information in credit markets. Within a stochastic overlapping-generations framework, we study the investment decision of entrepreneurs with heterogeneous abilities. Under information asymmetry, banks do not observe entrepreneurial ability and offer a single pooled loan contract to all entrepreneurs. We show that, following a
Difficult birth is the main contributor to birth-related fracture and accidents to other neonatal fractures
Aim: Specific birth-related fractures have been studied; underestimates might be a problem. We aimed to assess all fractures diagnosed as birth-related as well as other neonatal fractures. Methods: A population-based study on all infants born in Sweden 1997-2014; data were retrieved from the Swedish Health Registers (10th version of International Classification of Diseases. Outcome measures were b
Active chest tube clearance after aortic valve surgery did not influence amount residual pericardial fluid after aortic valve replacement in a randomised trial
Objective. Evaluate if the use of active clearance of chest tubes after aortic valve surgery influenced bleeding and reduced postoperative residual pericardial effusion. Design. Prospective randomised trial comparing PleuraFlow® 32 F chest tube with FlowGlide™ active clearance to a standard Argyle® 32 F chest tube in 100 patients undergoing aortic valve surgery. Chest tube outputs and pericardial
Policy Framework for Material Resource Efficiency : Pathway Towards a Circular Economy
The strategic direction of the European Union (EU) over the past twenty years has focused on increasing resource productivity and innovation in the economy, aiming at the efficient use and secured supplies of resources, economic growth and job creation, with fewer environmental impacts. One of the basic premises of the new ‘Green Deal’ for Europe is the promotion of the circular economy. The aim o
Political Exigency or religious affinity? Sectarianism in the contemporary Arab World
The STRIPAK Complex Regulates Response to Chemotherapy Through p21 and p27
The STRIPAK complex has been linked to a variety of biological processes taking place during embryogenesis and development, but its role in cancer has only just started to be defined. Here, we expand on previous work indicating a role for the scaffolding protein STRIP1 in cancer cell migration and metastasis. We show that cell cycle arrest and decreased proliferation are seen upon loss of STRIP1 i
Obsessive-compulsive symptoms and their links to depression and anxiety in clinic- and community-based pediatric samples: A network analysis
Background: Symptoms of depression and anxiety are common in children with obsessive-compulsive disorder (OCD) and associated with more severe OCD, greater impairment, and worse treatment outcome. Beyond twin studies showing that genetic factors contribute to the high co-occurrence, few studies have examined how OCD, depression, and anxiety are linked in youth, and current studies often fail to ac