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Method for evaluating learning from incidents using the idea of "level of learning"

Learning from incidents is considered a very important source for learning and improving safety in the process industries. However, the effectiveness of learning from reported incidents can often be ques-tioned. Therefore, there is a need to be able to evaluate the effectiveness of learning from incidents, and for that purpose we need methods and tools. In this paper, a method is described for eva

Identification of human S100A9 as a novel target for treatment of autoimmune disease via binding to quinoline-3-carboxamides.

Despite more than 25 years of research, the molecular targets of quinoline-3-carboxamides have been elusive although these compounds are currently in Phase II and III development for treatment of autoimmune/inflammatory diseases in humans. Using photoaffinity cross-linking of a radioactively labelled quinoline-3-carboxamide compound, we could determine a direct association between human S100A9 and

Lower Limb Amputation in Patients with Vascular Disease

Popular Abstract in Swedish Antalet personer som är amputerade ovanför tålederna i Sverige kan uppskattas till mellan 5000 och 5500. (ca 0.06 % av befolkningen). Största delen av dessa är amputerade pg.a. av kärlsjukdom (≈ 80 %). Antalet årligen nytillkomna benamputerade i Sverige kan uppskattas till mellan 1000-1100 och mindre än 5 % av dessa fall är relaterade till andra orsaker, t.ex. trauma elThe current prevalence of persons amputated at transmetatarsal level or higher in Sweden can be estimated to be between 5000 and 5500 persons (approx. 0.06 % of the population). The majority of these are patients with vascular disease (≈ 80%). In Sweden between 1000 and1100 new amputees can be expect every year. Less than 5% of all amputations will be related to causes other than vascular disease.

Effects of the DPP-4 Inhibitor Vildagliptin on Incretin Hormones, Islet Function, and Postprandial Glycemia in Subjects with Impaired Glucose Tolerance

Objective: This study was conducted to determine the effects of vildagliptin on incretin hormone levels, islet function, and postprandial glucose control in subjects with impaired glucose tolerance (IGT). Research Design and Methods: A 12-week double-blind, randomized, parallel-group study comparing vildagliptin (50 mg qd) and placebo was conducted in 179 subjects with IGT (2-h glucose= 9.1 mmol/l

What successful branding looks like: a managerial perspective

Purpose - The purpose of this paper is to develop an understanding of the ways in which food companies can work with branding to perform better in the market. The authors achieve this purpose by comparing how different managers of food brands prioritise and evaluate their brands, in relation to a theoretical ideal framework. Design/methodology/approach - A survey of 77 managers of domestic and int

On the suitability of carbon nanotube forests as non-stick surfaces for nanomanipulation

A carbon nanotube forest provides a unique non-stick surface for nanomanipulation, as the nanostructuring of the surface allows micro- and nanoscale objects to be easily removed after first being deposited via a liquid dispersion. A common problem for smooth surfaces is the strong initial stiction caused by adhesion forces after deposition onto the surface. In this work, carbon nanotube forests fa

Growth and characterization of superconducting beta-FeSe type iron chalcogenide nanowires

We have grown highly crystalline beta-FeSe type iron chalcogenide nanowires (NWs) by annealing thin film that is prepared by a pulsed laser deposition method. Three kinds of NWs with compositions of Fe0.8Se, Fe0.88Se0.32Te0.68 and Fe0.88Te0.91S0.09 have been prepared and carefully characterized by a high-resolution transmission electron microscope (HRTEM). The NWs reveal ideal tetragonal structure

Trope theory and the Bradley regress

Trope theory is the view that the world is a world of abstract particular qualities. But if all there is are tropes, how do we account for the truth of propositions ostensibly made true by some concrete particular? A common answer is that concrete particulars are nothing but tropes in compresence. This answer seems vulnerable to an argument (first presented by F. H. Bradley) according to which any

Towards imaging of ultrafast molecular dynamics using FELs

The dissociation dynamics induced by a 100 fs, 400 nm laser pulse in a rotationally cold Br-2 sample was characterized by Coulomb explosion imaging (CEI) using a time-delayed extreme ultra-violet (XUV) FEL pulse, obtained from the Free electron LASer in Hamburg (FLASH). The momentum distribution of atomic fragments resulting from the 400 nm-induced dissociation was measured with a velocity map ima

Malnutrition prevalence and precision in nutritional care differed in relation to hospital volume - a cross-sectional survey

Background: To explore the point prevalence of the risk of malnutrition and the targeting of nutritional interventions in relation to undernutrition risk and hospital volume. Methods: A cross-sectional survey performed in nine hospitals including 2 170 (82.8%) patients that agreed to participate. The hospitals were divided into large, middle, and small sized hospitals. Undernutrition risk and over

Integrin Based Isolation Enables Purification of Murine Lineage Committed Cardiomyocytes

In contrast to mature cardiomyocytes which have limited regenerative capacity, pluripotent stem cells represent a promising source for the generation of new cardiomyocytes. The tendency of pluripotent stem cells to form teratomas and the heterogeneity fromvarious differentiation stages and cardiomyocyte cell sub-types, however, are major obstacles to overcome before this type of therapy could be a

Linking Hydrogen (delta H-2) Isotopes in Feathers and Precipitation: Sources of Variance and Consequences for Assignment to Isoscapes

Background: Tracking small migrant organisms worldwide has been hampered by technological and recovery limitations and sampling bias inherent in exogenous markers. Naturally occurring stable isotopes of H (delta H-2) in feathers provide an alternative intrinsic marker of animal origin due to the predictable spatial linkage to underlying hydrologically driven flow of H isotopes into foodwebs. This

Womens' opinions on intrapartal care: development of a theory-based questionnaire

Aim. To develop a patient questionnaire specific to intrapartal care, based on the theoretical foundation of the general instrument Quality from the Patient's Perspective (QPP). Background. Existing general patient questionnaires do not take intrapartal care aspects fully into account, and available intrapartal-specific patient questionnaires tend to have a weak theoretical foundation. Design. A c

Measuring the glycemic index of foods: interlaboratory study

Background: Many laboratories offer glycemic index (GI) services. Objective: We assessed the performance of the method used to measure GI. Design: The GI of cheese-puffs and fruit-leather (centrally provided) was measured in 28 laboratories (n = 311 subjects) by using the FAO/WHO method. The laboratories reported the results of their calculations and sent the raw data for recalculation centrally.

The effects of an acceleration advisory tool in vehicles for reduced fuel consumption and emissions

This study evaluates whether the use of an acceleration advisor leads to fuel savings, to determine the change in traffic-related emissions and to analyse changes in driving patterns on various routes. The acceleration advisor provides advice to drivers through resistance in the accelerator pedal when they try to accelerate rapidly. In a test carried out in Southern Sweden, the acceleration adviso