Pharmacological interventions that combine pro-anabolic and anti-catabolic drugs to treat recalcitrant fractures have shown remarkable efficacy in augmenting the regenerative response. Specifically, in rodent models of fracture repair, treatment with BMP-7 and Zoledronate (ZA) has almost uniformally resulted in complete union. However, delayed remodeling may be problematic for ZA-treated fractures

The discovery, at the beginning of the 20th century, that elements can transform into other elements, due to the spontaneous decay of an instable to a stable atomic nuclei, gave rise to a powerful source for age information in many fields of earth science. For impact structures, it is crucial to establish well-defined and precise ages in order to understand how impact events affect the Earth’s geoThe discovery, at the beginning of the 20th century, that elements can transform into other elements, due to the spontaneous decay of an instable to a stable atomic nuclei, gave rise to a powerful source for age information in many fields of earth science. For impact structures, it is crucial to establish well-defined and precise ages in order to understand how impact events affect the Earth’s geo

A characterisation is given of bounded embeddings from weighted L2 spaces on bounded intervals into L2 spaces on the half-plane, induced by isomorphisms given by the Laplace transform onto weighted Hardy and Bergman spaces (Zen spaces). As an application necessary and sufficient conditions are given for the boundedness of truncated Hankel and Toeplitz integral operators, including the weighted cas

BibA, a group B streptococcus (GBS) surface protein, has been shown to protect the pathogen from phagocytic killing by sequestering a complement inhibitor: C4b-binding protein (C4BP). Here, the X-ray crystallographic structure of a GBS BibA fragment (BibA126-398) and a low-resolution small-angle X-ray scattering (SAXS) structure of the full-length N-terminal domain (BibA34-400) are described. The

We present the first application of a new approach, proposed in (2016 J. Phys. G: Nucl. Part. Phys. 43 04LT01) to derive coupling constants of the Skyrme energy density functional (EDF) from ab initio Hamiltonian. By perturbing the ab initio Hamiltonian with several functional generators defining the Skyrme EDF, we create a set of metadata that is then used to constrain the coupling constants of t

Serum vitamin D deficiency is widespread among older adults and is a potential modifiable risk factor for frailty. Moreover, frailty has been suggested as an intermediate step in the association between low levels of vitamin D and mortality. Hence, we conducted a systematic review of the literature and meta-analysis to test the possible association of low concentrations of serum 25-hydroxyvitamin

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Denna bok ger en integrerad framställning av de mestadels sakrättsliga aspekter som aktualiseras vid kreditgivning och finansiering, med särskilt fokus på realsäkerhetsfrågor.Boken inleds med en koncis översikt av ämnet sakrätt. Därefter följer presentationer av ägarförbehåll (återtagandeförbehåll) som kreditsäkerhet, olika slag av panträtt i lös egendom, fastighetspant och lagstiftningen om föret

Med projektet Ordbro sätter Centrum för Öresundsstudier fokus på och undersöker språk och språkkultur i det svenska och danska språket. Vi ber personer med olika bakgrund, inriktning och modersmål att utveckla hur de ser på ett visst danskt eller svenskt ord, begrepp eller talesätt.

Om vikten av att se till helheten när man jämför. Patrik Lindskoug, docent i civilrätt reflekterar över skillnader och likheter inom affärsjuridiken och samhällsstrukturer i Norden.

The hypothalamus is the central regulator of energy homeostasis. Hypothalamic neuronal circuits are disrupted upon overfeeding, and play a role in the development of metabolic disorders. While mouse models have been extensively employed for understanding the mechanisms of hypothalamic dysfunction, functional magnetic resonance imaging (fMRI) on hypothalamic nuclei has been challenging. We implemen