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Autoimmune Disease in Turner Syndrome in Sweden : An up to 25 Years' Controlled Follow-up Study

CONTEXT: Turner syndrome (TS) is the most common chromosomal aberration in women; it is the result of structural or numeric abnormalities in the X chromosome. Autoimmune hypothyroidism has been recognized as one of the more prominent disorders associated with TS. OBJECTIVE: This work aimed to study the prevalence of autoimmune diseases in TS. METHODS: A cross-sectional, longitudinal, 25-year follo

Atmospheric deposition and soil water chemistry in Swedish forests since 1985 – Effects of reduced emissions of sulphur and nitrogen

Trends for the atmospheric deposition of sulphur (S) and inorganic nitrogen (inorg-N) to forests and changes in the forest soil water chemistry in Sweden have been assessed since 1985, with special focus on the last 25 years, based on measurements within the Swedish Throughfall Monitoring Network (SWETHRO). The reductions in the deposition of S and inorg-N in the southern part of Sweden correspond

Artificial Intelligence-Based Organ Delineation for Radiation Treatment Planning of Prostate Cancer on Computed Tomography

Purpose: Meticulous manual delineations of the prostate and the surrounding organs at risk are necessary for prostate cancer radiation therapy to avoid side effects to the latter. This process is time consuming and hampered by inter- and intraobserver variability, all of which could be alleviated by artificial intelligence (AI). This study aimed to evaluate the performance of AI compared with manu

Batrachochytrium dendrobatidis strain affects transcriptomic response in liver but not skin in latitudinal populations of the common toad (Bufo bufo)

Batrachochytrium dendrobatidis (Bd) is a fungal pathogen that has decimated amphibian populations worldwide for several decades. We examined the changes in gene expression in response to Bd infection in two populations of the common toad, Bufo bufo, in a laboratory experiment. We collected B. bufo eggs in southern and northern Sweden, and infected the laboratory-raised metamorphs with two strains

The impact of late design choices on daylight and energy use in buildings

Daylight analysis is often carried out when definitive decisions about space characteristics such as materials, colours, window characteristics and furnishing have not yet been made. Such late design choices, which are first introduced or can still be changed late in the design process or even after its conclusion, impact the daylight levels of interior spaces. This study explored the impact of la

Anxiety, depression and quality of life in relation to SARS-CoV-2 antibodies in individuals living with diabetes during the second wave of COVID-19

Aims: The objective was to compare anxiety, depression, and quality of life (QoL) in individuals living with type 1 (T1D) and type 2 (T2D) diabetes with matched controls during the second wave of the COVID-19 pandemic. Methods: Via randomization, individuals living with diabetes T1D (n = 203) and T2D (n = 413), were identified during February-July 2021 through health-care registers. Population con

Ferroelectric Memristors - Materials, Interfaces and Applications

The backbone of modern computing systems rely on two key things: logic and memory, and while computing power hasseen tremendous advancements through scaling of the fundamental building block – the transistor, memory access hasn’tevolved as rapidly, leading to significant memory-bound systems. Additionally, the rapid evolution of machine learningand deep neural network (DNN) applications, has expos

Interim Report on Gribshunden (1495) Excavations: 2019–2021

We present an interim archaeological report on the ship- wreck of the Danish-Norwegian flagship Gribshunden. Built in 1485, extensively employed by King Hans as his floating castle, and ultimately lost in June 1495 en route to Kalmar, the ship carried people and material selected to further the political goal of re-unifying the Nordic region. Three field campaigns led by Lund University and Blekin

Proteomic analysis shows decreased type I fibers and ectopic fat accumulation in skeletal muscle from women with PCOS

Background: Polycystic ovary syndrome's (PCOS) main feature is hyperandrogenism, which is linked to a higher risk of metabolic disorders. Gene expression analyses in adipose tissue and skeletal muscle reveal dysregulated metabolic pathways in women with PCOS, but these differences do not necessarily lead to changes in protein levels and biological function. Methods: To advance our understanding of