Objective - To assess the effects of intraarticular injections of hyaluronan on symptoms of knee osteoarthritis (OA). Methods - Two hundred and forty patients with symptomatic, radiological knee OA were randomly assigned to treatment with weekly injections for five weeks with either 25 mg of high molecular weight hyaluronan or vehicle. Results were evaluated at weeks 1, 2, 3, 4, 5, 13, and 20 by v

Deep flexor tendons of 30 rabbits were divided at the ankle level. The effects of unloading on the synthesis and content of matrix components, the synthesis of DNA, and dry weight were investigated. The reaction of the fibrocartilaginous and non-fibrocartilaginous segments were separately analyzed. The ability of the tendons to synthesize collagen during short-term culture and the contents of matr

There is broad consensus that good outcome measures are needed to distinguish interventions that are effective from those that are not. This task requires standardized, patient-centered measures that can be administered at a low cost. We developed a questionnaire to assess short- and long-term patient-relevant outcomes following knee injury, based on the WOMAC Osteoarthritis Index, a literature re

While the term public diplomacy (PD) has undergone a major revival in the early 21st century, the evaluation of PD programs has not been given anywhere near the same level of attention. The number of studies which consider either the methods used for the evaluation of PD campaigns or the theoretical grounds of PD evaluation methodologies remain few compared to the number which discuss PD policy or

The book looks at corporate voluntarism from a socio-legal perspective and places CSR in a regulatory context. The responsible practices of leading businesses have a role in the rule-making process by clarifying general, flexible concepts such as ‘due diligence’, ‘reasonability’, ‘foreseeability’ which all have a bearing on findings of corporate ‘negligence’. Procedural regulations seeking to enco

The book looks at corporate voluntarism from a socio-legal perspective and places CSR in a regulatory context. The responsible practices of leading businesses have a role in the rule-making process by clarifying general, flexible concepts such as ‘due diligence’, ‘reasonability’, ‘foreseeability’ which all have a bearing on findings of corporate ‘negligence’. Procedural regulations seeking to enco

Prof. Ruggie’s work, with the ‘Protect, Respect and Remedy’ Framework (2008) and Guiding Principles (2011) as its peak, is multilayered and comprehensive. Instead of a dry, tedious description this introductory chapter will give the floor often to the SRSG: readers will find numerous quotations and references that will allow him or her to follow Ruggie’s reasoning. Ruggie should be commended for t

This chapter discusses the treatment that Professor Ruggie’s Guiding Principles offer for the responsibility to respect human rights (RtR) as applied to core companies whose affiliates’ operations infringe human rights. The issue is about a core company’s responsibility to act to address abuses that occur towards the periphery of its group or network. The fairness of globalisation is often questio

Atomic C, N, and O chemisorbed on Ni(100) have been studied by x-ray-absorption spectroscopy. The atomic 2p orbitals are shown to form hybrid orbitals with the Ni 3d and 4sp bands. The spectral contributions from these hybrids are identified at the absorption threshold and in a region 6-12 eV above this. Between those regions, states derived from atomic 3p and higher np orbitals are observed. The

The formation of Sm silicides on Si(111) by means of solid phase epitaxy has been studied with low energy electron diffraction, Auger electron spectroscopy and photoelectron spectroscopy of the Sm 4f level and Si 2p level. A limited reaction is found to occur already at room temperature whereas at higher temperatures a strongly intermixed Sm/Si layer showing some long range order is formed. The Sm

The ordered c(2×2) Na on Al(100) and (3 × 3) R30°K on Al(111) structures formed at either 100 K or at room temperature are studied by high-resolution core-level spectroscopy. For both systems equal alkali coverages are found at these two temperatures. The core-level spectra, however, show strong changes with temperature. This behavior leads to the surprising conclusion that annealing at room tempe

There is currently a widespread societal expectation for businesses to respect and support human rights. The apparent simplicity of this expectation contrasts sharply against the difficulty of specifying with precision the boundaries of corporate social responsibilities (CSR). This Article argues that the basis of these difficulties is the uncertainty regarding the responsibility of a business for

This collection gathers the more important instruments dealing with the relationships of business with a range of topics such as labor rights, security issues, environmental protection, anti-corruption, good governance, poverty alleviation and development, which all have important human rights dimensions. The premise for this selection is that business has both responsibilities and opportunities t