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Effects of acute stress provocation on cortisol levels, zonulin and inflammatory markers in low- and high-stressed men

The virtual version of the Trier Social Stress Test (V-TSST) is an effective and standardized tool for social stress induction. This study aimed to examine gut permeability and physiological and inflammatory markers of reactivity to acute psychosocial stress. Forty young men were classified as high-stressed (HIGHS) or low-stressed (LOWS) according to the Shirom-Melamed Burnout Questionnaire. Cardi

Quantum Transport in Superconductor-Semiconductor Nanowire Hybrid Devices

In this thesis, we study quantum transport properties of superconductor-semiconductor nanowire hybrid devices. We mainly focus on the quantum transport in InSb nanowire Josephson quantum dot devices, i.e. quantum dots coupled to two pieces of superconductors. In such a structure, many-body interacting phenomena occur, such as Kondo correlation, multiple Andreev reflection, and the formation of And

Effects of a pocket cavity on heat transfer and flow characteristics of the endwall with a bluff body in a gas turbine engine

A pocket cavity is generated at the connection of two parts, namely the transition part between the Low Pressure Turbine (LPT) and Outlet Guide Vane (OGV) in a gas turbine engine. This kind of pocket cavities, due to the high Reynolds number and the specific shapes, are hardly investigated in previous researches. In the present work, the effect of the pocket on the heat transfer of the endwall wit

Chapter 24, The Netherlands

This chapter discusses the tax gap in the Netherlands, access to information needed by the Dutch tax administration, exchange of information between the tax administration of the Netherlands and of other countries, cooperation between the Dutch tax administration and other Dutch law enforcement agencies, cooperative compliance and risk management in the Netherlands, the way the collection of taxes

Search for new phenomena using the invariant mass distribution of same-flavour opposite-sign dilepton pairs in events with missing transverse momentum in √s=13 Te pp collisions with the ATLAS detector

A search for new phenomena in final states containing an e+e- or μ+μ- pair, jets, and large missing transverse momentum is presented. This analysis makes use of proton–proton collision data with an integrated luminosity of 36.1fb-1, collected during 2015 and 2016 at a centre-of-mass energy s=13TeV with the ATLAS detector at the Large Hadron Collider. The search targets the pair production of super

Search for pair production of heavy vector-like quarks decaying into high-p T W bosons and top quarks in the lepton-plus-jets final state in pp collisions at √s=13 TeV with the ATLAS detector

A search is presented for the pair production of heavy vector-like B quarks, primarily targeting B quark decays into a W boson and a top quark. The search is based on 36.1 fb−1 of pp collisions at s=13 TeV recorded in 2015 and 2016 with the ATLAS detector at the CERN Large Hadron Collider. Data are analysed in the lepton-plus-jets final state, characterised by a high-transverse-momentum isolated e

Spices in the postprandial metabolic regulation of healthy humans : An integrated physiological and omics approach

Metabolic syndrome (MetS) is a consequence of obesity and defined as cluster of at least three out of five criteria covering insulin resistance/glucose intolerance, abdominal obesity, hypertension, low HDL-c and elevated TG levels. Imbalance between energy intake and expenditure is known to alter normal physiological function in many aspects, and leads to obesity, which in the long run may turn in

Not all those who wander are lost : A study of cancer cells by digital holographic imaging, fluorescence and a combination thereof

Cancer är den näst vanligaste dödsorsaken i världen idag och en tredjedel av Sveriges befolkning blir diagnosticerade med cancer under sin livstid. Av alla cancerfall i Sverige, så är prostatacancer den vanligaste och bröstcancer den näst vanligaste, medan hos enbart kvinnor så är bröstcancer den vanligaste med 29,2 % av cancerfallen. Överlevnaden efter en cancerdiagnos har i Sverige ökat sedan 70Cells are commonly used in research to evaluate toxicity and efficiency of drugs. However, to further increase the usefulness of cells as well as the understandings of effects of different interventions, new methods must constantly be developed and refined. Today, many assays use end-point analysis of large populations of cells, to evaluate the research question. However, there are many cases when

Measurements of b-jet tagging efficiency with the ATLAS detector using tt¯ events at √s=13 TeV

The efficiency to identify jets containing b-hadrons (b-jets) is measured using a high purity sample of dileptonic top quark-antiquark pairs (tt¯) selected from the 36.1 fb−1 of data collected by the ATLAS detector in 2015 and 2016 from proton-proton collisions produced by the Large Hadron Collider at a centre-of-mass energy s=13 TeV. Two methods are used to extract the efficiency from tt¯ events,

Neutral pion and η meson production in p–Pb collisions at √sNN = 5.02 TeV

Neutral pion and η meson invariant differential yields were measured in non-single diffractive p–Pb collisions at sNN = 5.02 TeV with the ALICE experiment at the CERN LHC. The analysis combines results from three complementary photon measurements, utilizing the PHOS and EMCal calorimeters and the Photon Conversion Method. The invariant differential yields of π0 and η meson inclusive production are

Enhanced expression of MycN/CIP2A drives neural crest toward a neural stem cell-like fate : Implications for priming of neuroblastoma

Neuroblastoma is a neural crest-derived childhood tumor of the peripheral nervous system in which MycN amplification is a hallmark of poor prognosis. Here we show that MycN is expressed together with phosphorylation-stabilizing factor CIP2A in regions of the neural plate destined to form the CNS, but MycN is excluded from the neighboring neural crest stem cell domain. Interestingly, ectopic expres

The new LUCID-2 detector for luminosity measurement and monitoring in ATLAS

The ATLAS luminosity monitor, LUCID (LUminosity Cherenkov Integrating Detector), had to be upgraded for the second run of the LHC accelerator that started in spring 2015. The increased energy of the proton beams and the higher luminosity required a redesign of LUCID to cope with the more demanding conditions. The novelty of the LUCID-2 detector is that it uses the thin quartz windows of photomulti

Detector rates for the Small Angle Neutron Scattering instruments at the European Spallation Source

Building the European Spallation Source (ESS), the most powerful neutron source in the world, requires significant technological advances at most fronts of instrument component design. Detectors are not an exception. The existing implementations at current neutron scattering facilities are at their performance limits and sometimes barely cover the scientific needs. At full operation the ESS will y

Linking developmental diet to adult foraging choice in Drosophila melanogaster

Rather than maximizing intake of available macronutrients, insects increase intake of some nutrients and restrict intake of others. This selective consumption influences, and potentially optimizes, developmental time, reproduction and lifespan of the organism. Studies so far have focused on discriminating between protein and carbohydrate uptake and the consequences on fitness components at differe

Genome-wide regulatory deterioration impedes adaptive responses to stress in inbred populations of Drosophila melanogaster : inbreeding under stress assessed by RNAseq

Inbreeding depression is often intensified under environmental stress (i.e., inbreeding–stress interaction). Although the fitnessconsequences of this phenomenon are well-described, underlying mechanisms such as an increased expression of deleterious allelesunder stress, or a lower capacity for adaptive responses to stress with inbreeding, have rarely been investigated. We investigated afitness compon

Shouting at the wall : Does negativity drive ideological cross-posting in Brexit Facebook comments?

Using a novel methodological approach to measure emotions in Facebook comments, this Work in Progress (WIP) paper explores the relationship between negative feelings and ideological cross-posting behavior. Using the VoxPopuli data harvester, we collect over 770,000 public Facebook comments1 from the three major political campaign pages active during the Brexit referendum. After sorting users into

Spectacular language and creative marketing in a Singapore tailor shop

A tailor shop located in Singapore’s Chinatown is explored as a case of creative linguistic marketing practice, examining how such practice can be understood in relation to the interaction of local and global forces on the linguistic landscape. The shop uses a range of Scandinavian semiotic resources (language and artefacts) which for us, coming upon the shop, seemed unexpected or, using Sweetland

Spatial Separation of Closely-Located Users in Measured Massive MIMO Channels

We investigate the ability of Massive multiple-input multiple-output (MIMO) systems to spatially separate up to eighteen users located close to one another in line-of-sight (LOS) propagation conditions, in both indoor and outdoor environments. For that, we use fully-synchronous measured channels at 2.6 GHz of single-antenna users moving within a small area and concurrently communicating with a bas

Clinical impact of direct stenting and interaction with thrombus aspiration in patients with ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention : Thrombectomy Trialists Collaboration

Aims Preliminary studies suggest that direct stenting (DS) during percutaneous coronary intervention (PCI) may reduce microvascular obstruction and improve clinical outcome. Thrombus aspiration may facilitate DS. We assessed the impact of DS on clinical outcome and myocardial reperfusion and its interaction with thrombus aspiration among ST-segment elevation myocardial infarction (STEMI) patients