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A Study on Evaporative Resistances of Two Skins Designed for Thermal Manikin Tore under Different Environmental Conditions

A cotton skin and a waterproof but permeable Gore-Tex skin were designed for the thermal manikin “Tore” to simulate different sweating styles (the wet cotton skin inside and Gore-Tex skin outside to simulate the sweating style of thermal manikin “Walter”, and Gore-Tex skin inside with wet cotton skin outside to simulate the sweating style of thermal manikins “Newton”). The evaporative resistances

Being next of kin to an elderly person with cancer

Objectives: The aim of the study was to illuminate the experience of life as next of kin to an elderly person with cancer. Background: Being next of kin to an elderly person with cancer and its impact on everyday life has been sparsely researched. Such understanding is needed to support both the sufferers and their relatives in dealing with issues arising after a cancer diagnosis in old age. Desig

Nano particles as the primary cause for long-term sunlight suppression at high southern latitudes following the Chicxulub impact - evidence from ejecta deposits in Belize and Mexico

Life on Earth was sharply disrupted 66 Ma ago as an asteroid hit the sea-floor in what is today Yucatan Peninsula, Mexico. Approximately 600 km(3) of sedimentary rock were vapourized, ejected into the atmosphere and subsequently deposited globally as an ejecta apron and fallout layer. Proximal ejecta deposits occur in Belize and southern Mexico where the so called Albion island spheroid bed is sup

Numerical Prediction Tools for Low-Frequency Sound Insulation in Lightweight Buildings

Lightweight wooden-framed constructions have steadily increased their market share in Sweden during the last two decades. Achieving acoustic and vibration comfort in wooden-based buildings is, however, still a challenging task. Wood is high in both strength and stiffness in relation to its weight, but its variability has repercussions on how sound propagates, this triggering sound insulation probl

Multiculturalism, Recogntion and the 'Kurdish Question' in Turkey: The Outline of a Normative Framework

Despite the ever-growing literature on various aspects of the Kurdish question in Turkey, there are practically no normative discussions of Kurdish demands for the public recognition of their identities. This is all the more startling given the ascendancy of philosophical accounts in the literature on minority rights. This article will try to redress the balance by proposing a normative framework

Experimental studies of sorption and transport of moisture in cement based materials with supplementary cementitious materials

Most deterioration processes in cement based materials are closely related to moisture sorption and moisture transport properties. Therefore, it is important to study these properties, both theoretically and practically. This work is an experimental investigation in this field. Nowadays, the cement industry produces cements with increasing amounts of supplementary cementitious materials (SCMs) to

Cardiomyocyte Cell Cycle, Renewal and Isolation

Popular Abstract in Swedish Hjärtsjukdom som orsakas av skador på hjärtmuskelceller är en av de vanligaste dödsorsakerna världen över. En framtida önskvärd behandling vore att kunna stimulera kroppens egna förmåga att återskapa hjärtmuskelceller, eller att isolera hjärtmuskelceller framställda i cellkultur. Arbete I är fokusera på studier rörande tillväxtmönstret hos hjärtmuskelceller under normaHeart disease results from the loss of cardiomyocytes following myocardial damage and is a leading cause of death worldwide. Stimulating the endogenous regeneration of cardiomyocytes or isolating them from in vitro culture is an attractive therapeutic strategy. In paper I, the focus is on the cellular growth patterns of murine cardiomyocytes under steady-state conditions. The turnover of cardiomyo

Exhaled Breath Temperature Increases after Exercise in Asthmatics and Controls.

Background: Exhaled breath temperature (EBT) has been suggested as a marker of airway inflammation in asthma. Objectives: The aim of the present study was to investigate EBT in asthmatic subjects compared to healthy controls after an exercise challenge test, and in subjects with exercise-induced bronchoconstriction compared to subjects without, and to compare with body temperatures. Methods: A tot

A Systematic Review of the Volume-Outcome Relationship for Radical Prostatectomy

Context: Due to the complexity and challenging nature of radical prostatectomy (RP), it is likely that both short-and long-term outcomes strongly depend on the cumulative number of cases performed by the surgeon as well as by the hospital. Objective: To review systematically the association between hospital and surgeon volume and perioperative, oncologic, and functional outcomes after RP. Evidence

TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival.

Nuclear orphan receptor TLX (Drosophila tailless homolog) is essential for the maintenance of neural stem/progenitor cell self-renewal, but its role in neuroblastoma (NB) is not well understood. Here, we show that TLX is essential for the formation of tumor spheres in three different NB cell lines, when grown in neural stem cell media. We demonstrate that the knock down of TLX in IMR-32 cells dimi

Increase of beta-Lactam-Resistant Invasive Haemophilus influenzae in Sweden, 1997 to 2010

The proportions of Haemophilus influenzae resistant to ampicillin and other beta-lactam antibiotics have been low in Sweden compared to other countries in the Western world. However, a near-doubled proportion of nasopharyngeal Swedish H. influenzae isolates with resistance to beta-lactams has been observed in the last decade. In the present study, the epidemiology and mechanisms of antimicrobial r

Neuromuscular Versus Quadriceps Strengthening Exercise in Patients With Medial Knee Osteoarthritis and Varus Malalignment

Objective. To compare the effects of neuromuscular exercise (NEXA) and quadriceps strengthening (QS) on the knee adduction moment (an indicator of medio-lateral distribution of knee load), pain, and physical function in patients with medial knee joint osteoarthritis (OA) and varus malalignment. Methods. One hundred patients with medial knee pain, mostly moderate-to-severe radiographic medial knee

Permanent Distal Occlusion of Middle Cerebral Artery in Rat Causes Local Increased ETB, 5-HT1B and AT(1) Receptor-Mediated Contractility Downstream of Occlusion

Background/Aims: In response to experimental stroke, a characteristic functional and expressional upregulation of contractile G-protein-coupled receptors has been uncovered in the affected cerebral vasculature; however, the mechanism initiating this phenomenon remains unknown. Methods: Using a model of permanent distal occlusion of rat middle cerebral arteries, we investigated whether there was a

Health effects associated with foods characteristic of the Nordic diet: a systematic literature review

Background: In preparing the fifth edition of the Nordic Nutrition Recommendations (NNR), the scientific basis of specific food-based dietary guidelines (FBDG) was evaluated. Objective: A systematic review (SR) was conducted to update the NNR evidence based on the association between the consumption of potatoes, berries, whole grains, milk and milk products, and red and processed meat, and the ris

Viral vector-mediated overexpression of α-synuclein as a progressive model of Parkinson's disease

The discovery of the role of α-synuclein in the pathogenesis of Parkinson's disease (PD) has opened new possibilities for the development of more authentic models of Parkinson's disease. Recombinant adeno-associated virus (AAV) and lentivirus (LV) vectors are efficient tools for expression of genes locally in subsets of neurons in the brain and can be used to express human wild-type or mutated α-s