Search results

Filter

Filetype

Your search for "*" yielded 528970 hits

Second malignancies after childhood noncentral nervous system solid cancer: results from 13 cancer registries

Children diagnosed with noncentral nervous system solid cancers (NCNSSC) experience several adverse late effects, including second malignant neoplasm. The aim of our study was to assess the risk of specific second malignancies after a childhood NCNSSC. Diagnosis and follow-up data on 10,988 cases of NCNSSC in children (0-14 years) were obtained from 13 registries. Standardized incidence ratios (SI

Water sorption isotherms of Kraft lignin and its composites

The water sorption properties of Kraft lignin before and after treatment with the enzyme laccase, and its composites with branched polyethylenimine and chitosan, respectively, have been studied. The experimental sorption isotherms were obtained by dynamic vapour sorption (DVS) method. The data were analysed using the Brunauer–Emmett–Teller (BET) and Guggenheim–Anderson–de Boer (GAB) models. Monola

Antihypertensive Therapy Is Associated with Reduced Rate of Conversion to Alzheimer's Disease in Midregional Proatrial Natriuretic Peptide Stratified Subjects with Mild Cognitive Impairment

Background: Hypertension is a major risk factor of Alzheimer's disease (AD); however, controlled studies on the effect of antihypertensive treatment on the risk of dementia are inconclusive. Therefore, a biological marker that predicts individual response to antihypertensive treatment would be of high clinical relevance. Midregional proatrial natriuretic peptide (MR-proANP), an inactive surrogate

Why do seals have cones? Behavioural evidence for colour-blindness in harbour seals.

All seals and cetaceans have lost at least one of two ancestral cone classes and should therefore be colour-blind. Nevertheless, earlier studies showed that these marine mammals can discriminate colours and a colour vision mechanism has been proposed which contrasts signals from cones and rods. However, these earlier studies underestimated the brightness discrimination abilities of these animals,

Conjugated heat transfer analysis of a film cooling passage with different rib configurations

Purpose - The purpose of this paper is to analyze the effect of thermal conductivity on gas turbine blades, and to investigate the contribution of different rib configurations to the heat flux and the film cooling effectiveness. Design/methodology/approach - The Renormalization Group (RNG) model with enhanced wall treatment was used for the turbulence modeling, and the SIMPLE algorithm was used to

Interaction and Aggregation of Charged Platelets in Electrolyte Solutions: A Coarse-Graining Approach.

A coarse-graining approach has been developed to replace the effect of explicit ions with an effective pair potential between charged sites in anisotropic colloidal particles by optimizing a potential of mean force against the results of simulations of two such colloidal particles with all ions in a cell model. More specifically, effective pair potentials were obtained for charged platelets in ele

Ethical aspects of undergoing a predictive genetic testing for Huntington's disease.

The aim of this study was to describe the experiences of undergoing a presymptomatic genetic test for the hereditary and fatal Huntington's disease, using a case study approach. The study was based on 18 interviews with a young woman and her husband from the decision to undergo the test, to receiving the results and trying to adapt to them, which were analysed using a life history approach. The fi

Rational design of D-A1-D-A2 conjugated polymers with superior spectral coverage.

The spectral coverage of a light-harvesting polymer largely determines the maximum achievable photocurrent in organic photovoltaics, and therefore constitutes a crucial parameter for improving their performance. The D-A1-D-A2 copolymer motif is a new and promising design strategy for extending the absorption range by incorporating two acceptor units with complementary photoresponses. The fundament

Differential localization and characterization of functional calcitonin gene-related peptide receptors in human subcutaneous arteries.

Calcitonin gene-related peptide (CGRP) and its receptor are widely distributed within the circulation and the mechanism behind its vasodilation not only differs from one animal species to another but is also dependent on the type and size of vessel. The present study examines the nature of CGRP-induced vasodilation, characteristics of the CGRP receptor antagonist telcagepant and localization of th

Near Ambient Pressure X-ray Photoelectron Spectroscopy Study of the Atomic Layer Deposition of TiO2 on RuO2(110)

The atomic layer deposition (ALD) of TiO2 on a RuO2(110) surface from tetrakis(dimethylamido) titanium and water at 110 degrees C was investigated using near ambient pressure X-ray photoelectron spectroscopy (NAP-XPS) at precursor pressures up to 0.1 mbar. In addition to the expected cyclic surface species, evidence for side reactions was found. Dimethylamine adsorbs on the surface during the TDMA

Diagnosis-Independent Alzheimer Disease Biomarker Signature in Cognitively Normal Elderly People

Objective: To identify biomarker patterns typical for Alzheimer disease (AD) in an independent, unsupervised way, without using information on the clinical diagnosis. Design: Mixture modeling approach. Setting: Alzheimer's Disease Neuroimaging Initiative database. Patients or Other Participants: Cognitively normal persons, patients with AD, and individuals with mild cognitive impairment. Main Outc

Approximation algorithms for optimal purchase/inventory policy when purchase price and demand are stochastic

We consider a purchase/inventory control problem in which the purchase price and demand are stochastic, a common situation encountered by firms that replenish in a foreign currency or from commodity markets. More specifically, we assume that the demand follows a Poisson arrival process and that the log-price evolves according to a general Wiener process. Under these circumstances, the optimal poli

Does income-related health inequality change as the population ages? Evidence from Swedish panel data

This paper explains and empirically assesses the channels through which Population aging may impact on income-related health inequality. Long panel data of Swedish individuals is used to estimate the observed trend in income-related health inequality, measures by the concentration index (CI). A decomposition procedure based on a fixed effects model is used to clarify the channels by which populati

Detrital zircon signatures of the Baltoscandian margin along the Arctic Circle Caledonides in Sweden: The Sveconorwegian connection

New evidence is presented here that the Sveconorwegian Orogen continued northwards from type areas in southwestern Scandinavia along the Baltoscandian outer margin into the high Arctic. The Silver Road (Silvervagen) profile through the Scandinavian Caledonides, located in Sweden along the Arctic Circle at 66-67 degrees N, provides a full section through the tectonostratigraphy of the Baltoscandian

One-Dimensional Corrugation of the h-BN Monolayer on Fe(110)

We report on a new nanopatterned structure represented by a single atomic layer of hexagonal boron nitride (h-BN) forming long periodic waves on the Fe(110) surface. The growth process and the structure of this system are characterized by X-ray absorption (XAS), core-level photo-emission spectroscopy (CL PES), low-energy electron microscopy (LEEM), microbeam low-energy electron diffraction (mu LEE

The Autism-Tics, AD/HD and other Comorbidities (A-TAC) telephone interview: Convergence with the Child Behavior Checklist (CBCL).

Objective: To compare telephone interview screening for child psychiatric/neuropsychiatric disorders using the inventory of Autism-Tics, Attention deficit/hyperactivity disorder (AD/HD) and other Comorbidities (A-TAC) with results from the Child Behavior Checklist (CBCL). Background: The A-TAC is a parent telephone interview focusing on autism spectrum disorders (ASDs) and co-existing problems, de

Immune responses to hair dyes containing toluene-2,5-diamine

Background Toluene-2,5-diamine (PTD) is the most frequently used dye in oxidative hair dyes on the Scandinavian market. However, little is known about immune responses to PTD-containing oxidative hair dyes. Objectives To study immune responses induced by PTD-containing hair dyes in mice. Methods Immune responses against two different permanent hair dye products containing 1·60% (w/w) and 0·48%