Sepsis is a systemic host response to invasive infection by bacteria. Despite treatment with antibiotics, current mortality rates are in the range of 20%-25%, which makes sepsis the most important cause of death in intensive care. Gram-negative bacteria are a prominent cause of sepsis. Lipopolysaccharide (LPS), one of the major constituents of the outer membrane of Gram-negative bacteria, plays a

Methylmercury (MeHg) toxicity may vary widely despite similar levels of exposure. This is hypothetically related to genetic differences in enzymes metabolizing MeHg. MeHg causes oxidative stress in experimental models but little is known about its effects on humans. The aims of the present study was to evaluate the effects of polymorphisms in glutathione (GSH)-related genes (GSTM1, GSTT1, GSTP1 an

Abstract in Undetermined A classical solution for matching two image patches is to use the cross-correlation coefficient. This works well if there is a lot of structure within the patches, but not so well if the patches are close to uniform. This means that some patches are matched with more confidence than others. By estimating this uncertainty, more weight can be put on the confident matches thaA classical solution for matching two image patches is to use the cross-correlation coefficient. This works well if there is a lot of structure within the patches, but not so well if the patches are close to uniform. This means that some patches are matched with more confidence than others. By estimating this uncertainty, more weight can be put on the confident matches than those that are more unc

This study compared the caring situation, health, self-efficacy, and stress of young (16-25) informal carers (YICs) supporting a family member with mental illness with that of YICs supporting a friend. A sample of 225 carers, assigned to a family group (n = 97) or a friend group (n = 128) completed the questionnaire. It was found that the family group experiences a lower level of support and frien

We aimed to validate a widely used US prediction model for vaginal birth after cesarean (Grobman et al. [8]) and modify it to suit Swedish conditions.

The ATLAS experiment at the LHC has measured the production cross section of events with two isolated photons in the final state, in proton-proton collisions at root s = 7 TeV. The full data set collected in 2011, corresponding to an integrated luminosity of 4.9 fb(-1), is used. The amount of background, from hadronic jets and isolated electrons, is estimated with data-driven techniques and subtra

Mammographic density is an established risk factor for breast cancer; however, the relation to tumor pathological parameters including the androgen receptor and molecular subtypes has not been extensively studied.

In order to better address the feedbacks between climate and wetland methane (CH4) emissions, we tested several mechanistic improvements to the wetland CH4 emission model Peatland-VU with a longer Arctic data set than any other model: (1) inclusion of an improved hydrological module, (2) incorporation of a gross primary productivity (GPP) module, and (3) a more realistic soil-freezing scheme. A lo

A fundamental aspect in the regulation of the continuity of electricity supply is the identification of faults that could be caused by an exceptional event and, therefore, that are outside the utility control and responsibility. Different methods have been proposed during the years: the interpretation of the observed faults as a signal of an underlying system naturally leads to the analysis of the

To determine the relationship between changes in antibody levels towards citrullinated peptides derived from different candidate autoantigens and therapeutic outcome in early rheumatoid arthritis (RA).

Cancer of unknown primary (CUP) is diagnosed at the metastatic stage and despite extensive diagnostic work-up the primary tumor often remains unidentified. Limited population-based survival data are available for metastatic location and none are available that link the location with the cause of death, which might give clues about the tissue of origin. A total of 9,306 CUP patients with extranodal

Objective: Data remain divergent regarding the activational effects of endogenous hormones on adult cognitive function. We examined the association between cognition, hormones and androgen receptor (AR) CAG repeat length in a large cohort of men. Design: Community-based, cross-sectional study of 3369 men aged 40-79 years. Methods: Cognition tests were the Rey-Osterrieth Complex Figure, Camden Topo

We investigate the construction of tree-level MHV gluon amplitudes in multiplet bases using BCFW recursion. The multiplet basis decomposition can either be obtained by decomposing results derived in (for example) the DDM basis or by formulating the recursion directly in the multiplet basis. We focus on the latter approach and show how to efficiently deal with the color structure appearing in the r

Life threatening arrhythmias are increasingly frequent with lower body temperature. While targeted temperature management (TTM) with mild hypothermia following out-of-hospital cardiac arrest (OHCA) is generally considered safe and has been suggested as a potential antiarrhythmic add-on therapy, it is unknown whether the level of TTM affects the burden of ventricular ectopic activity. We sought to

By applying the recently developed model REVEALS (Regional Estimates of VEgetation Abundance from Large Sites) (Sugita, 2007) to pollen data from a large number of sites across Northern Germany and Denmark, we construct maps of regional patterns in landscape openness and in cover abundance of key plant taxa in the cultural landscape of north-central Europe for selected time slices in the Holocene.