Functional Studies of Telomere-Binding Proteins in Saccharomyces castellii
Telomeres are the ends of linear eukaryotic chromosomes. The telomeres are essential for solving the end replication problem and they stabilize the genome by protection from degradation. The telomeres also protect the chromosomal ends from by being recognized as DNA breaks by the repair machinery, which could lead to end-to-end fusions. Dysfunctional telomeres are implicated in many complex cellul