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The ability of the proinflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) to influence epithelial interleukin (IL)-8 responses to the intestinal bacterium Lactobacillus plantarum 299v was analyzed in the human HT-29 colonic epithelial cell line. In the absence of TNF-alpha, IL-8 mRNA expression was not detectable by Northern blot analysis in HT-29 cells alone or in HT-29 cells co-culture
Detecting and estimating long-range dependence are important in the analysis of many environmental time series. This article proposes a periodogram roughness (PR) estimator and describes its uses for testing and estimating the dependence structure. Asymptotic critical values are generated for performing the test, and special attention is given to investigating the properties of the PR regarding si
Mercury and selenium in whole blood and serum of 245 17-year old Swedish adolescents were analysed. The relationships between these elements' concentrations and the consumption of fish as well as the number of dental amalgam fillings were studied. The geometric means (GM) of the mercury concentrations were 1.1 mug/L in blood and 0.43 mug/L in serum. The mean selenium concentration in blood was 110
This paper presents selected findings from the project 'Privatisation of public housing in Hanoi, the impacts on housing quality and social equality' which was financed by the Swedish International Development Authority (SIDA). The project analyses the consequences of privatisation on the housing conditions of those tenants and owners who live in privatised and partly privatised multi family apart
The aim of this work is to quantitatively compare two commonly used beam quality indices, IPR(20/10) and %dd(10)x, with respect to their ability to predict stopping power ratios (water to air), s(w,air), for high-energy x-rays. In particular, effects due to a varied amount of filtration of the photon beam will be studied. A new method for characterizing beam quality is also presented, where the in
The modeling of soot formation and oxidation under industrially relevant conditions has made significant progress in recent years. Simplified models introducing a small number of transport equations into a CFD Code have been used with some success in research configurations simulating a reciprocating diesel engine. Soot formation and oxidation in the turbulent flow is calculated on the basis of a
Aim: Studying changes between the ages of 20 and 35 in the use of alcohol and its meaning to the user and the relation of this to cultural background. Data and method: Qualitative interviews with 42 persons in Malmö, Sweden, aged approximately 20 years (21 women and 21 men) belonging to 3 groups, differing in social characteristics in their use of alcohol and the meaning it had for them. 34 of the
BACKGROUND: Oxidative stress and related DNA damage in human sperm may be important for fecundity and pregnancy outcome. METHODS: We studied the level of oxidative DNA damage in terms of 7-hydro-8-oxo-2'-deoxyguanosine (8-oxodG) in sperm DNA among 225 first-pregnancy planners. Over the six menstrual cycle follow-up time, after cessation of contraception, 135 pregnancies were conceived. RESULTS: Th
BACKGROUND Calcium (Ca2+) supplementation has been shown paradoxically to reduce intracellular Ca2+ and induce vascular relaxation. The aim of the study was to assess 24-h blood pressure (BP) change after Ca2+ supplementation and to investigate its relation to changes in intracellular ions and the activity of the first isoform of sodium-hydrogen exchange (NHE-1) in subjects with hypertension and t
Experience in using rapidly internalizing antibodies, such as the anti-CD22 antibody, for radioimmunotherapy of B-cell lymphomas is still limited. The present study was conducted to assess the efficacy and toxicity of a 131I-labeled anti-CD22 monoclonal antibody (mAb), LL2, in patients with B-cell lymphomas failing first- or second-line chemotherapy. Eligible patients were required to have measura
It is known that solid phase microextraction (SPME) fibers can be equilibrated directly within environmental matrices such as water, sediment and soil slurries. Here it is shown that this method can also be applied to biological tissue. SPME extraction of biological matrices reportedly causes lipophilic fouling of the fiber. However, we found no significant measurement bias when combining equilibr
Abstract is not available
Introduction: The gene encoding TGFBI is a strong functional candidate for genetic susceptibility to osteoporosis. Several polymorphisms have been identified in TGFB1, and previous work has suggested that allelic variants of TGFBI. may regulate BMD and susceptibility to osteoporotic fracture. Materials and Methods: We studied the relationship between common polymorphisms of TGFBI and several osteo
Rectal swabs were collected from Antarctic fur seal pups Arctocephalus gazella at Cape Shirreff, South Shetland Islands, and analyzed for the presence of anthropogenic pathogens. Two of the 33 pups tested positive for enteropathogenic Escherichia coli (EPEC). These samples are the first records of EPEC in Antarctic wildlife and suggest that more needs to be done to protect the Antarctic fauna from
A technique based on progressive fumigation was used to reduce soil microbial biodiversity, and the effects of such reductions upon the stability of key soil processes were measured. Mineral soil samples from a grassland were fumigated with chloroform for up to 24 h and then incubated for 5 months to allow recolonisation by surviving organisms. The diversity of cultivable and non-cultivable bacter
The immunotoxin 192 IgG-saporin induces an efficient and specific lesion of low-affinity nerve growth factor receptor-bearing cholinergic neurons in the basal forebrain. Intraventricular injection of 192 IgG-saporin, which caused a complete loss of cholinergic afferents to the hippocampus and neocortex and a partial denervation of amygdala and piriform cortex, was found to markedly facilitate the
The evolution of female promiscuity poses an intriguing problem as benefits of mating with multiple males often have to arise via indirect, genetic, effects. Studies on birds have documented that multiple paternity is common in natural populations but strong evidence for selection via female benefits is lacking. In an attempt to evaluate the evidence more broadly, we review studies of multiple pat
