Background: Neuroblastoma (NB) tumours are commonly divided into three cytogenetic subgroups. However, by unsupervised principal components analysis of gene expression profiles we recently identified four distinct subgroups, r1-r4. In the current study we characterized these different subgroups in more detail, with a specific focus on the fourth divergent tumour subgroup (r4). Methods: Expression

The significant defect-induced increase in transconductance at high frequencies in some III-V MOSFETs is utilized to reveal the spatial distribution and energy profile of traps in the gate dielectric. The frequency response of the border traps is modeled as a distributed RC network inserted in the small signal model. Surface-channel InGaAs MOSFETs with Al2O3/HfO2 high-k gate dielectric are evaluat

We demonstrate changes in ecosystem stable states in a coastal lagoon that are consistent with what a regime shift would hypothesize. In the nutrient-stressed Ringkobing Fjord, Denmark, a small change in one variable (salinity) facilitated by a change in sluice management, caused a sudden regime shift from a bottom-up controlled turbid state, into a top-down controlled clear-water state. The chang

Lund University, Sweden, is the only seat of learning having Sociology of Law (hereafter SoL) at all levels in Europe. SoL was initiated in 1972 as a department at the Social Science Faculty, with professor Per Stjernquist as chair. Later on, for some 10 years, SoL was a division within the department of Sociology but from January 2006, SoL is an autonomous department at the Social Science Faculty

The current control design development process in automotive industry and elsewhere involves many expensive experiments and hand-tuning of control parameters. Model based control design is a promising approach to reduce costs and development time. In this process low complexity models are essential and model reduction methods are very useful tools. This thesis combines the areas of modeling and mo

Nanoscale contacts between metals and semiconductors are critical for further downscaling of electronic and optoelectronic devices. However, realizing nanocontacts poses significant challenges since conventional approaches to achieve ohmic contacts through Schottky barrier suppression are often inadequate. Here we report the realization and characterization of low n-type Schottky barriers (~0.35 e

The inflammatory mediator procalcitonin (PCT) has previously been associated with prognosis in myocardial infarction, cancer and sepsis patients. The importance of PCT in the general population is currently unknown. Our aim was to assess the relationship between plasma PCT and the risk of all-cause and cause-specific mortality in apparently healthy individuals with no previous history of cardiovas

Neutron dark-field imaging constitutes a seminal progress in the field of neutron imaging as it combines real space resolution capability with information provided by one of the most significant neutron scattering techniques, namely small angle scattering. The success of structural characterizations bridging the gap between macroscopic and microscopic features has been enabled by the introduction

The oxidized Ag(111) surface has been studied by a combination of experimental and theoretical methods, scanning tunneling microscopy, x-ray photoelectron spectroscopy, and density functional theory. A large variety of different surface structures is found, depending on the detailed preparation conditions. The observed structures fall into four classes: (a) individually chemisorbed atomic oxygen a

Popular Abstract in Swedish Bakgrund Kroniskt obstruktiv lungsjukdom (KOL) är en vanlig orsak till död världen över och dödligheten ökar främst bland kvinnor. Patienter med kronisk syrebrist på grund av KOL behandlas med hemsyrgas (LTOT), men har mycket hög dödlighet. Kunskapen är idag bristfällig kring könsskillnader och tidstrender i dödlighet och dödsorsaker, betydelsen av andra sjukdomar (samsBackground Chronic obstructive pulmonary disease (COPD) is a major and rising cause of mortality worldwide, especially in women. Patients with chronic hypoxia owing to COPD are treated with long-term oxygen therapy (LTOT) but have high morbidity and mortality. Knowledge is limited on sex-related differences and time trends in mortality, effects of comorbidity on mortality and whether cardiovascula

This study traces the history of publishers’ cloth-bindings in Sweden, and places them in relation to the emergence of modernity. The interaction between techno-logy, economics and aesthetics is central to the analysis, in which a sociological approach is combined with per-spectives of book history and material culture studies. • The study consists of two parts: Book culture in transit-ion, mainly

Traces of Danish-Norwegian Church life in South and Western Sweden did not disappear after 1658. Rather the nineteenth and twentieth century changes of Church structure and services weakened or dispersed of the Danish traces. But then they were not any more interpreted as Danish. The ongoing, frequent amalgamation of parishes means a final break with the original, Danish Church structure in the co

The article relates the concept of God's "plan" in Job 38:2 and 42:3 to similar concepts in earlier Ancient Near Eastern mythological literature, especially the term niklātu ("wise, ingenious things") used in the Babylonian Enuma Elish to describe the actions of Marduk - both the battle against the chaos monster Tiamat and the creation of the earthly world. Parallels are also drawn to expressions

A method is described for imaging in 3-D the interiors of meteoritic chromite grains and their inclusions using synchrotron radiation X-ray tomographic microscopy. In ordinary chondrites, chromite is the only common mineral that survives long-term weathering on Earth. Information about the silicate matrix of the original meteorite, however, can be derived from mineral inclusions preserved in the p

The variability of health complaints within individuals across time has rarely been studied, and the question whether between- and within-person factor structures of health-related variables are equivalent has not been tested so far. We examined self-reported health complaints in 101 younger (20-31 years) and 103 older adults (65-80 years) over a period of 100 daily assessments. Data were analyzed