BACKGROUND: Analyses of clinical outcomes following radiotherapy (RT) have advanced our understanding of fundamental radiobiological characteristics in head and neck squamous cell carcinoma (HNSCC). Low fractionation sensitivity appears to be a common feature, as well as susceptibility to changes in overall treatment time (OTT). Large tumors should be harder to cure if a successful RT requires the

Behövs kontor? I kölvattnet av pandemins distansarbete är det frestande att utropa kontorets undergång. Men då glöms det bort att kontoret är så mycket mer än en plats där arbetsuppgifter utförs. Kontorets plats nu och i framtiden diskuteras i denna gästkrönika i Forte Magasin.

While recent technological advancements have enabled improved performance in warehouse operations, companies still struggle with eliminating errors such as incorrect/damaged items or the wrong quantity sent to customers. Such errors result in inefficient resource use, costly returns handling, and customer dissatisfaction. Despite the importance of errors, current knowledge of the underlying causes

We present a method to produce small pitch gratings for X-ray interferometric imaging applications, allowing the phase sensitivity to be increased and/or the length of the laboratory setup to be minimized. The method is based on fabrication of high aspect ratio silicon microstructures using deep reactive ion etching (Bosch technique) of dense grating arrays and followed by conformal electroplating

Protein translocation across the endoplasmic reticulum (ER) membrane is an essential step during protein entry into the secretory pathway. The conserved Sec61 protein-conducting channel facilitates polypeptide translocation and coordinates cotranslational polypeptide-processing events. In cells, the majority of Sec61 is stably associated with a heterotetrameric membrane protein complex, the transl

The theme of ICIS 2013 in Milan is "Reshaping Society through Information Systems" (http://icis2013.aisnet.org/). One aspect of reshaping society that has been recently discussed in central Europe is that of social inclusion (http://ec.europa.eu/social/main.jsp?catId=750&langId=en). Yet, after decades of research and ambitious political programs, we still observe an imbalanced treatment toward

The goal of this study is to identify the perspectives that development NGOs attribute to organisational social media, and furthermore elaborate on an appropriate categorisation of these perspectives for social media use by development NGOs. How social media is used in the area of development, where the use goes far beyond the private sector purpose of publicity and converting a sale, is a key iss

OBJECTIVE: Sex steroids exert important biological functions within the central nervous system (CNS), but the underlying mechanisms are poorly understood. The contribution of circulating sex steroids to the levels in CNS tissue and cerebrospinal fluid (CSF) has been sparsely investigated in human and with inconclusive results. This could partly be due to lack of sensitive validated assays. To addr

The quantum mechanical equivalent of the classical Hall effect can lead to interesting results in solid state physics.A similar effect, that has received attention in recent years, occurs when large spin-orbit coupling is present in a material, the so-called quantum-spin Hall effect.In two-dimensional materials it leads to so-called helical edge states that exhibit counter-propagating electron sta

Climate policies are often assumed to have significant impacts on the nature and speed of energy transitions. To investigate this hypothesis, we develop an approach to categorise, trace, and compare energy transitions across countries and time periods. We apply this approach to analyse electricity transitions in the G7 and the EU between 1960 and 2022, specifically examining whether and how climat

This book charts the shifting boundaries of Judaism from antiquity to the modern period in order to bring clarity to what scholars mean when they claim that ancient texts or groups are “within Judaism,” as well as exploring how rabbinic Jews, Christians, and Muslims have negotiated and renegotiated what Judaism is and is not in order to form their own identities. Belief in Jesus as the Messiah was

Policies on preventing radicalization and recruitment to violent Islamist organizations have been widely criticized for reinforcing negative stereotypes of Muslims as a group. Sweden has stood out by international comparison by announcing an approach built on inclusion and participation, especially with regard to Muslim civil society. But what does it mean to make a policy process inclusive and pa

We investigate the problem of risk averse robot path planning using the deep reinforcement learning and distributionally robust optimization perspectives. Our problem formulation involves modelling the robot as a stochastic linear dynamical system, assuming that a collection of process noise samples is available. We cast the risk averse motion planning problem as a Markov decision process and prop

This thesis seeks to examine the suitability and robustness of transfer learning models in creating an efficient reCAPTCHA v2 classifier, and further evaluates their performance against various adversarial attacks. Three models - DenseNet201, EfficientNetV2, and InceptionV3 - were trained and assessed, highlighting the applicability of transfer learning techniques in the classification of reCAPTCH

We formulate a version of the low-scale Majoron model equipped with an inverse seesaw mechanism featuring lepton-number preserving dimension-6 operators in the scalar potential. Contrary to its dimension-4 counterpart, we find that the model can simultaneously provide light and ultralight Majorons, neutrino masses and their mixing, while featuring strong first-order cosmological phase transitions