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The yield of screening symptomatic contacts of multidrug-resistant tuberculosis cases at a tertiary hospital in Addis Ababa, Ethiopia.

BackgroundEarly detection and treatment of multidrug-resistant tuberculosis (MDR-TB, resistant to isoniazid and rifampicin) is an urgent global priority. Identifying and tracing close contacts of patients with MDR-TB could be a feasible strategy to achieve this goal. However, there is limited experience with contact tracing among patients with drug-resistant tuberculosis both globally and in Ethio

Collaboratively reframing mental health for integration of HIV care in Ethiopia

Background Integrating mental health with general medical care can increase access to mental health services, but requires helping generalists acquire a range of unfamiliar knowledge and master potentially complex diagnostic and treatment processes.Method We describe a model for integrating complex specialty care with generalist/primary care, using as an illustration the integration of mental heal

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Since 1995, agri-environmental support partly funded by the EU has formed the core of Finland’s agri-environmental policy. This system has had a variety of impacts on the relationship between agriculture and the environment. Today’s agri-environmental support is one of the packages included in the Rural Development Programme for Mainland Finland (2007–2013/2014), which both in itself and through t

Optimal wound closure of diabetic foot ulcers with early initiation of TLC-NOSF treatment : Post-hoc analysis of Explorer

Objective: In March 2018, the Explorer study, an international, double-blind, randomised controlled trial (RCT), established that adding a TLC-NOSF (UrgoStart Contact, Laboratoires Urgo, France) dressing to good local standard of care (SoC) significantly and substantially increases wound closure and reduces the healing time of neuroischaemic diabetic foot ulcers (DFU). Besides the TLCNOSF treatmen

Effect of assisted walking-movement in patients with genetic and acquired neuromuscular disorders with the motorised Innowalk device : an international case study meta-analysis

People with physical disabilities (PD) suffer from consequences due to lack of physical activity and consequently, are at increased risk of chronic diseases. We aimed to evaluate the ability of a motorised assistive device for dynamic standing with weight-bearing in addition to standard state-of-the-art therapy to improve clinical outcome in a meta-analysis of available studies. A total of 11 stud

Anaerobes in industrial- and environmental biotechnology

Anaerobic microorganisms present in diverse ecological niches employ alternative strategies for energy conservation in the absence of oxygen which enables them to play a key role in maintaining the global cycles of carbon, nitrogen, and sulfur, and the breakdown of persistent compounds. Thereby they become useful tools in industrial and environmental biotechnology. Although anaerobes have been rel

Levels of islet amyloid polypeptide in cerebrospinal fluid and plasma from patients with Alzheimer’s disease

The biologically active pancreatic hormone peptide islet amyloid polypeptide (IAPP) regulates brain functions such as appetite and cognition. It also plays a role in clearance of amyloid beta (Aβ), a peptide implicated in the dementia disorder Alzheimer’s disease (AD). If IAPP becomes modified, it loses its biological activity and starts to aggregate. Such aggregations have been found in the AD br

Högintensiv träning – En träningsform med möjlighet att påverka metabolismen.

Rekommendationerna för hur träning bör formas för att ge största möjliga hälsovinster har ändrats genom tiderna. Under 90-talet sökte man en nedre gräns gällande intensitet på träningen för att få en träningseffekt. Under 2000-talet växte sedan tankar kring träning på recept fram och koncepten FaR och FYSS myntades. Syftet med träning på recept är dubbelt, både primär- och sekundärprevention. Vid

Out of Space

An academic journal is a special place – even more so an online journal. On the one hand, it is surely one of the main stages of professional qualification, presentation and academic discourse, though regulated through its gatekeeping structures of peer review, official invitation, of academic critique and corrections: it represents an open and accessible, yet not unregulated public space in the b