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Burning a holy book: the dilemma of free speech

In recent weeks, Sweden has experienced several Quran-burning incidents. These can reinforce anti-religious discourse and politicised campaigns against religious minorities. They can also put Swedish multicultural harmony at risk. Azher Hameed Qamar argues that we must interpret the laws permitting Quran-burnings as being in the best interest of the people

gatukonst

Definition of street art for The National Encyclopedia of Sweden.

Definitive aetiology of unexplained syncope after cardiovascular autonomic tests in a tertiary syncope unit

BACKGROUND AND AIM: Syncope is a common condition with many possible causes, ranging from benign to life-threatening aetiologies. Establishing a diagnosis can be difficult and specialized syncope units, using cardiovascular autonomic tests (CAT) including head-up tilt test can increase the diagnostic yield. However, up to one fifth of examined patients have inconclusive CAT results. The aim of the

A Systematic Review of Mesenchymal Epithelial Transition Factor (MET) and Its Impact in the Development and Treatment of Non-Small-Cell Lung Cancer.

Lung cancer represents the leading cause of annual cancer-related deaths worldwide, accounting for 12.9%. The available treatment options for patients who experience disease progression remain limited. Targeted therapeutic approaches are promising but further understanding of the role of genetic alterations in tumorigenesis is imperative. The MET gene has garnered great interest in this regard. Th

Theoretical and Practical Aspects of Space-Time DG-SEM Implementations

We discuss two approaches for the formulation and implementation of space-time discontinuous Galerkin spectral element methods (DG-SEM). In one, time is treated as an additional coordinate direction and a Galerkin procedure is applied to the entire problem. In the other, the method of lines is used with DG-SEM in space and the fully implicit Runge–Kutta method Lobatto IIIC in time. The two approac

A Second‑Order Finite Volume Method for Field‑Scale Reservoir Simulation

Subsurface reservoirs are large complex systems. Reservoir flow models are defined on complex grids that follow geology with relatively large block sizes to make consistent simulations feasible. Reservoir engineers rely on established reservoir simulation software to model fluid flow. Nevertheless, fluid front position inaccuracies and front smearing on large grids may cause significant errors and

Climate-change worry among two cohorts of late adolescents : Exploring macro and micro worries, coping, and relations to climate engagement, pessimism, and well-being

Few studies have explored climate change worry in an in-depth manner among adolescents. Through survey studies with two cohorts of adolescents (2010, 2019/2020) we investigated relations between different forms of climate change worry, mental well-being, and pro-environmental behavior and what role coping plays in these relationships. Results show that climate change worry was negatively associate

How people update their beliefs about climate change : An experimental investigation of the optimistic update bias and how to reduce it

People usually update their beliefs selectively in response to good news and disregard bad news. Here, we investigated in two preregistered experiments (N = 278 and N = 306) (1) whether such valence-dependent belief updating also underlies information processing in the context of climate change and (2) whether it can be altered by interventions informing about different aspects of climate change.

“Toxic, but in a good way” : H&M in Russia during the Ukraine war as seen through consumer activism on TikTok

While scholars have explored how business has increasingly been involved in socio-political issues (Scherer et al., 2016; van der Meer & Jonkman, 2021), less attention has been given to the process of how businesses are held accountable for those issues by stakeholders (Reinecke & Ansari, 2016). Current studies show that multinational corporations are sometimes forced to take a stand on di

Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia

Frontotemporal dementia (FTD) is the second most prevalent type of early-onset dementia and up to 40% of cases are familial forms. One of the genes mutated in patients is CHMP2B, which encodes a protein found in a complex important for maturation of late endosomes, an essential process for recycling membrane proteins through the endolysosomal system. Here, we have generated a CHMP2B-mutated human

Assessment of the TRX2p-yEGFP Biosensor to Monitor the Redox Response of an Industrial Xylose-Fermenting Saccharomyces cerevisiae Strain during Propagation and Fermentation

The commercial production of bioethanol from lignocellulosic biomass such as wheat straw requires utilizing a microorganism that can withstand all the stressors encountered in the process while fermenting all the sugars in the biomass. Therefore, it is essential to develop tools for monitoring and controlling the cellular fitness during both cell propagation and sugar fermentation to ethanol. In t

Optimization of a hybrid bacterial/Arabidopsis thaliana fatty acid synthase system II in Saccharomyces cerevisiae

Fatty acids are produced by eukaryotes like baker's yeast Saccharomyces cerevisiae mainly using a large multifunctional type I fatty acid synthase (FASI) where seven catalytic steps and a carrier domain are shared between one or two protein subunits. While this system may offer efficiency in catalysis, only a narrow range of fatty acids are produced. Prokaryotes, chloroplasts and mitochondria rely

Playing in the moral imaginary : Interacting with monsters and animals in The Witcher 3: The Wild Hunt

This paper explores the dark gothic fantasy world of The Witcher 3: The Wild Hunt, an open-world video game from 2015. Using The Witcher 3 as a case study, the paper examines the moral dimensions of player interaction within the game beyond dialogue trees and NPC interaction. By investigating how the player is presented with monsters and animals within the game world, the paper makes an argument f

Industry-funding for Ph.D. students : benefits and challenges

This paper investigates employment outcomes for a large sample of Ph.D. students who were enrolled in a doctoral training program in Italy in the period 2008–14. The empirical analysis is based on survey data obtained from a questionnaire distributed to 23,500 individuals in 2016. In Italy, student enrolment in a Ph.D. involves a university-based selection process; most students then receive eithe

Identify novel elements of knowledge with word embedding

As novelty is a core value in science, a reliable approach to measuring the novelty of scientific documents is critical. Previous novelty measures however had a few limitations. First, the majority of previous measures are based on recombinant novelty concept, attempting to identify a novel combination of knowledge elements, but insufficient effort has been made to identify a novel element itself

Measuring risk in science

Risk plays a fundamental role in scientific discoveries, and thus it is critical that the level of risk can be systematically quantified. We propose a novel approach to measuring risk entailed in a particular mode of discovery process – knowledge recombination. The recombination of extant knowledge serves as an important route to generate new knowledge, but attempts of recombination often fail. Dr

Probabilistic solutions to ordinary differential equations as nonlinear Bayesian filtering: a new perspective

We formulate probabilistic numerical approximations to solutions of ordinary differential equations (ODEs) as problems in Gaussian process (GP) regression with nonlinear measurement functions. This is achieved by defining the measurement sequence to consist of the observations of the difference between the derivative of the GP and the vector field evaluated at the GP—which are all identically zero