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Learning to Care, Learning to Be Affected: A Study of Two Public Spaces Designed to Counter Segregation

In response to social fragmentation and segregation, public space is increasingly conceived of as an instrument for fostering openness towards differences. Drawing on two recent public spaces—Superkilen in Copenhagen, Denmark, and Jubileumsparken in Gothenburg, Sweden—this article explores the ethical potential of two different design approaches to the sharing of public space—designing for an ethi

Vascular function in adults with cyanotic congenital heart disease

Background: Patients with cyanotic congenital heart disease (CCHD) may have a low burden of atherosclerosis. Endothelial dysfunction is an early stage of atherosclerosis and endothelial function is previously studied in smaller CCHD groups with different techniques and variable results. We aimed to examine endothelial function and carotid atherosclerosis in a larger group of CCHD patients. Methods

Modes of climate variability : Synthesis and review of proxy-based reconstructions through the Holocene

Modes of climate variability affect global and regional climates on different spatio-temporal scales, and they have important impacts on human activities and ecosystems. As these modes are a useful tool for simplifying the understanding of the climate system, it is crucial that we gain improved knowledge of their long-term past evolution and interactions over time to contextualise their present an

The costs and benefits of paternal care in fish : a meta-analysis

Male-only parental care, while rare in most animals, is a widespread strategy within teleost fish. The costs and benefits to males of acting as sole carer are highly variable among fish species making it challenging to determine the selective pressures driving the evolution of male-only care to such a high prevalence. We conducted a phylogenetic meta-analysis to examine the costs and benefits of p

Spin-orbit-resolved spectral phase measurements around a Fano resonance

We apply a spectrally-resolved electron interferometry technique to the measurement of the spectral phase in the vicinity of the 3s13p64p Fano resonance of argon. We show that it allows disentangling the phases of the two nearly-overlapping electron wavepackets corresponding to different spin-orbit final states. Using simple assumptions, it is possible to process the experimental data and numerica

Tuning the selective permeability of polydisperse polymer networks

We study the permeability and selectivity ('permselectivity') of model membranes made of polydisperse polymer networks for molecular penetrant transport, using coarse-grained, implicit-solvent computer simulations. In our work, permeability P is determined on the linear-response level using the solution-diffusion model, P = KDin, i.e., by calculating the equilibrium penetrant partition ratio K and

Meaningful Activities and Recovery (MA&R) : the effect of a novel rehabilitation intervention among persons with psychiatric disabilities on activity engagement-study protocol for a randomized controlled trial

BACKGROUND: Engagement in activities meaningful to the individual may support the process of recovery in those with mental illness. Persons with psychiatric disabilities may reduce their engagement in meaningful activities to various degrees with possible fluctuations over time. We hypothesized that activity engagement can be altered when opportunities and support are offered at an individual and

Hydration-Induced Structural Changes in the Solid State of Protein : A SAXS/WAXS Study on Lysozyme

The stability of biologically produced pharmaceuticals is the limiting factor to various applications, which can be improved by formulation in solid-state forms, mostly via lyophilization. Knowledge about the protein structure at the molecular level in the solid state and its transition upon rehydration is however scarce, and yet it most likely affects the physical and chemical stability of the bi

New Light on the Mechanism of Phototransduction in Phototropin

Phototropins are photoreceptor proteins that regulate blue light-dependent biological processes for efficient photosynthesis in plants and algae. The proteins consist of a photosensory domain that responds to the ambient light and an output module that triggers cellular responses. The photosensory domain of phototropin from Chlamydomonas reinhardtii contains two conserved LOV (light-oxygen-voltage

Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein

Background: α-Synuclein (aSyn) aggregation is thought to play a central role in neurodegenerative disorders termed synucleinopathies, including Parkinson's disease (PD). Mouse aSyn contains a threonine residue at position 53 that mimics the human familial PD substitution A53T, yet in contrast to A53T patients, mice show no evidence of aSyn neuropathology even after aging. Here, we studied the neur

MBBRs as post-treatment to ozonation : Degradation of transformation products and ozone-resistant micropollutants

The degradation potential of micropollutants and transformation products in biological post-treatment after ozonation is partly unknown. A pilot plant with ozonation and subsequent biological treatment in a moving bed biofilm reactor (MBBR) was thus operated over 16 months to investigate the removal of micropollutants and the formation and removal of N-oxide transformation products. Lab-scale kine

Frequency Recognition Algorithm for Multiple Exposures : Snapshot imaging using coded light

The central challenge tackled in this thesis is the development of an optical imaging approach capable of multidimensional image capture of dynamic samples. Many conventional optical imaging approaches, which can obtain dimensional information such as spectral, polarisation, or volumetric, to name a few, about samples either employ sequential image capture or parallelised detector arrangements. Du

Biochemical signatures reveal positive effects of conservation tillage on arbuscular mycorrhizal fungi but not on saprotrophic fungi and bacteria

Since tillage can reduce the amount of organic C stored in soils, the use of conservation tillage practices, which exclude soil inversion, or include it less frequently, is often promoted. Soil microorganisms are closely linked to soil organic C (SOC), and they are assumed to respond quicker to management changes than SOC. Using two Swedish long-term tillage experiments, our aim was to determine w

Photofunctionality of iron(III) N-heterocyclic carbenes and related d5 transition metal complexes

Despite a few reports of photoluminescent and strongly photo-oxidizing transition metal complexes with a d5 electronic configuration, the photophysics and photochemistry of this class of transition metal complexes have largely remained unexplored. Recent investigations of earth-abundant iron(III) N-heterocyclic carbene (NHC) complexes have demonstrated promising photophysical and photochemical pro

Europe in Historical International Relations

Almost any conversation about Historical International Relations (IR) appears to be, at least implicitly, always already about Europe. The geographical and intellectual centrality of Europe shapes the way in which historically oriented work in IR operates. Paradoxically, despite a long and powerful lineage of disciplinary Eurocentrism, Europe has only rarely emerged as a conceptual focal point of