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Equivalence and polyvalence : A case for the stratification of semantics

The article presents a semantic theory suggesting that equivalence and polyvalence are closely connected phenomena. The connection between them is utilised by making equivalence the basis of an argument for polyvalence within semantics, or in other terms, for a stratified semantics encompassing two levels of description. This argument from equivalence lends new support to frameworks assuming a str

Motstridigheter : Om upplevda integrationsproblem och formuleringen av svensk integrationspolicy

During 2014–2016, Sweden received almost 300,000 people seeking protection. Politically, this asylum reception has been presented as a “crisis”, and a threat to the welfare system as well as Swedish culture. At the same time, many argue that immigration contributes to society's prosperity, both culturally and economically. The aim of this ethnographic study is to examine how problems are formulate

Misdiagnosis of Rheumatoid Arthritis in a Long-Term Cohort of Early Arthritis Based on the ACR-1987 Classification Criteria

Objective: Correct diagnosis of early rheumatoid arthritis (RA) is essential for optimal treatment choices. No pathognomonic test is available, and diagnosis is based on classification criteria, which can result in misdiagnosis. Here, we examined the differences between actual and misdiagnosed RA cases in a long-term cohort of patients included based on the ACR-1987 classification criteria. Method

DeepRecon : Joint 2D Cardiac Segmentation and 3D Volume Reconstruction via a Structure-Specific Generative Method

Joint 2D cardiac segmentation and 3D volume reconstruction are fundamental in building statistical cardiac anatomy models and understanding functional mechanisms from motion patterns. However, due to the low through-plane resolution of cine MR and high inter-subject variance, accurately segmenting cardiac images and reconstructing the 3D volume are challenging. In this study, we propose an end-to-

A CHEOPS-enhanced view of the HD 3167 system

Much remains to be understood about the nature of exoplanets smaller than Neptune, most of which have been discovered in compact multi-planet systems. With its inner ultra-short period planet b aligned with the star and two larger outer planets d-c on polar orbits, the multi-planet system HD 3167 features a peculiar architecture and offers the possibility to investigate both dynamical and atmosphe

Retinal toxicity in a multinational inception cohort of patients with systemic lupus on hydroxychloroquine

Objective To evaluate hydroxychloroquine (HCQ)-related retinal toxicity in the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort. Methods Data were collected at annual study visits between 1999 and 2019. We followed patients with incident SLE from first visit on HCQ (time zero) up to time of retinal toxicity (outcome), death, loss-to-follow-up or end of study. Potential r

One-Year Treatment Outcomes of Secukinumab Versus Tumor Necrosis Factor Inhibitors in Spondyloarthritis : Results From Five Nordic Biologic Registries Including More Than 10,000 Treatment Courses

Objective: To describe baseline characteristics and to compare treatment effectiveness of secukinumab versus tumor necrosis factor inhibitors (TNFi) in patients with spondyloarthritis (SpA) using adalimumab as the main comparator. Methods: This was an observational, prospective cohort study. Patients with SpA (clinical ankylosing spondylitis, nonradiographic axial SpA, or undifferentiated SpA) sta

The interaction between smoking and bladder cancer genetic variants on urothelial cancer risk by disease aggressiveness

Background: Smoking has shown interactions with bladder cancer (BC) genetic variants, especially N-acetyltransferase-2 (NAT2), a tobacco smoke metabolism gene, on BC risk. The interactions by disease aggressiveness are unknown. Methods: We investigated the interaction between smoking and 18 single nucleotide polymorphisms (SNPs) for BC, individually and in a genetic risk score (GRS), on urothelial

A unified design proposal for shear stress prediction in crossing areas for cross laminated timber at in-plane shear and beam loading conditions

Environmental and urbanization challenges during the last few decades encouraged steady growth of mass timber construction where attention is drawn to cross laminated timber (CLT) as one of the most interesting products in terms of mechanical properties, versatility, efficient prefabrication and sustainability. Standardisation and codification regarding testing and design of CLT elements are hence

Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes

Febrile seizures represent the most common type of pathological brain activity in young children and are influenced by genetic, environmental and developmental factors. In a minority of cases, febrile seizures precede later development of epilepsy. We conducted a genome-wide association study of febrile seizures in 7635 cases and 83 966 controls identifying and replicating seven new loci, all with

The Limits of Intergovernmental Flexibility in EU Law: Evidence from the Irish Opt-out in the Area of Freedom, Security and Justice and the New Surrender Mechanism with the UK

This paper discusses the limits of intergovernmental flexibility in the area of freedom, security and justice with a main focus on the case of SN and SD. The judgment represents the first legal challenge to the new surrender mechanism between the EU and the UK post-Brexit. Reflecting on general criteria of legal basis litigation, the crux of the matter concerns the Irish opt-out under Protocol No

Prediction of Hospitalizations in Systemic Lupus Erythematosus Using the Systemic Lupus International Collaborating Clinics Frailty Index

Objective: The Systemic Lupus International Collaborating Clinics (SLICC) frailty index (FI) predicts mortality and damage accrual in systemic lupus erythematosus (SLE), but its association with hospitalizations has not been described. Our objective was to estimate the association of baseline SLICC-FI values with future hospitalizations in the SLICC inception cohort. Methods: Baseline SLICC-FI sco

Cost-effectiveness of cervical length screening and progesterone treatment to prevent spontaneous preterm delivery in Sweden

Objective: To estimate the cost-effectiveness of strategies to prevent spontaneous preterm delivery (PTD) in asymptomatic singleton pregnancies, using prevalence and healthcare cost data from the Swedish healthcare context. Methods: We designed a decision analytic model based on the Swedish CERVIX study to estimate the cost-effectiveness of strategies to prevent spontaneous PTD in asymptomatic wom

Comparative analysis of planted and unplanted controls for assessment of rhizosphere priming effect

The rhizosphere priming effect (RPE) is increasingly being considered to be an important regulator of soil organic matter (SOM) decomposition and nutrient turnover, with potential importance for the global CO2 budget. As a result, studies on the RPE have rapidly increased in number over the last few years. Most of these experiments have been performed using unplanted soil as the control, which cou

Differences in accumulation of polycyclic aromatic compounds (PACs) among eleven broadleaved and conifer tree species

PACs (polycylic aromatic compounds) are air pollutants formed in incomplete combustion, e.g., in vehicle engines. Vegetation can potentially remove substantial amounts and act as bioindicators of these pollutants. Increased knowledge of the pollutant removal efficiencies of different tree species is essential for understanding the potential benefits trees can provide urban residents. We investigat

Nonoccupational Allergic Contact Dermatitis to 4-Acryloylmorpholine in Smartwatch Screen Protectors Glue

Background We recently identified an outbreak of occupational allergic contact dermatitis (ACD) involving workers of a Spanish company selling smartphone protective cases from a glue product. A chemical analysis of one glue sample revealed the presence of 4-acryloylmorpholine among other allergens. The same glue is also used to attach tempered glass protective cases to Apple smartwatches. Objectiv