Over 14 000 patients aged 15-24 are estimated to be diagnosed with cancer in the European Union (EU) each year. Teenagers and young adults (TYA) often fall down gaps between children's and adults cancer services. The specific challenges of providing optimal care to them are described, but we present a summary of recent progress. Progress to overcome these challenges is happening at different rates

Present knowledge on natural history and how to treat penetrating aortic ulcers or different forms of pseudoaneurysms with or without infection is limited as there are only case reports and small series of unusual aortic pathology and its treatment available. MATERIAL: From our centre we collected 65 patients treated with open (n = 15) or endovascular reconstruction (n= 50) during a 20-year period

Calculation of Box Compression Resistance (BCR) is a challenging task and here the possibility of an engineering approach is considered. The strive has been towards obtaining a simple and general predictive tool with as few parameters as possible and still obtaining an accurate estimate of the BCR. The model proposed is based on the concept of dividing the package into panels and corner panels. Wi

A predictive genetic test for Huntington's disease can be used before any symptoms are apparent, but there is only sparse knowledge about the long-term consequences of a positive test result. Such knowledge is important in order to gain a deeper understanding of families' experiences.

Background: Some studies have suggested a lower incidence of cancer in patients with dementia. We studied this further for 18 cancer types in population-based registers. Methods: In 19,756 cases and in 147,324 age- and sex-matched controls a diagnosis of dementia was studied 9-45 months prior to the diagnosis of cancer. Results: Overall a diagnosis of dementia was significantly less common among t

Treatment of Mv1Lu mink lung epithelial cells with transforming growth factor-beta 1 (TGF-beta 1) prevents phosphorylation of the retinoblastoma susceptibility gene product, RB, in late G1 phase of the cell cycle, which is thought to retain RB in a growth-suppressive state. This effect is paralleled by cell cycle arrest in late G1 (M. Laiho, J. A. DeCapric, J. W. Ludlow, D. M. Livingston, and J. M

Background/Aims: Experimental studies have suggested that trypsinogen may enhance tumor progression and that the ratio between anionic trypsinogen and cationic trypsinogen (HAT/HCT) and between the sum of trypsinogens and pancreatic secretory trypsin inhibitor (PSTI) ((HAT + HCT)/PSTI) are disturbed in patients with pancreatic cancer. The aim of this study was to investigate if pre-diagnostic leve

OBJECTIVE: To examine the number of trials needed to achieve performance stability of the Timed Up & Go (TUG) test using a standardized walking aid in patients with hip fracture who are allowed full weight bearing (FWB). DESIGN: Prospective methodologic study. SETTING: An acute 14-bed orthopedic hip fracture unit. PARTICIPANTS: Patients (N=122; 89 women, 33 men) with hip fracture wit

Radiative lifetimes of two levels in Ce I, eight levels in Ce rr, and nine levels in Ce III have been measured using the time-resolved laser-induced fluorescence technique. Free cerium atoms and singly and doubly ionized ions were obtained in a laser-produced plasma. A narrow bandwidth UV laser pulse was employed to selectively populate the short-lived upper levels and the lifetime values were eva

Experiences of relocation in dementia care from the perspective of six care workers. International Journal of Older People Nursing6, 93-101 doi: 10.1111/j.1748-3743.2010.00246.x Background. Relocation of persons with dementia might be considered when quality of care cannot be sustained due to increasing needs. Relocation has been studied from the aspects of mortality and morbidity. Aim. To explore

The simultaneous measurement of thousands of genes gives the opportunity to personalize and improve cancer therapy. In addition, the integration of meta-data such as protein-protein interaction (PPI) information into the analyses helps in the identification and prioritization of genes from these screens.Here, we describe a computational approach that identifies genes prognostic for outcome by comb

The directional stability of an originally straight crack under symmetric remote loading is studied after introduction of an infinitesimal disturbance at one or both tips of the crack. The crack is assumed to grow slowly under vanishing mode II stress intensity factor. Directional stability is defined to prevail if the angle formed by the straight line between the crack tips and the original crack

PURPOSE: Treatment with calcium channel blockers have been associated with increased colon cancer mortality in epidemiologic studies. We examined the potential expression and function of calcium channels in two human colon cancer cell lines. METHODS: Both primary (collected at operation) and commercially-available human colon cancer cell lines were used. The colon cancer cells were incubated with

We aimed to investigate the etiology and clinical management of vaginal bleeding in girls aged 0-9 years and to compare our results with previous publications.

Questions concerning the human–nature relationship have received attention both within contemporary Christianity and Buddhism. Since the twentieth century an interesting and fruitful dialogue has been going on between the two religions. This article describes and discusses possible themes for a Buddhist–Christian dialogue on issues of environmental philosophy. The theoretical starting-point is the

Approximately 8% of clear cell renal cell carcinoma cases contain regions of radically different morphology, demonstrating a mesenchymal appearance histologically resembling sarcomas. These biphasic neoplasms are called sarcomatoid clear cell renal cell carcinoma. Patients diagnosed with sarcomatoid clear cell renal cell carcinoma face a considerably worse prognosis due to an increased propensity