Purpose: Biomedical data governance strategies should ensure that data are collected, stored, and used ethically and lawfully. However, research participants’ preferences for how data should be governed is least studied. The Diabetes Research on Patient Stratification (DIRECT) project collected substantial amounts of health and genetic information from patients at risk of, and with type II diabete

Importance: Low academic achievement (AA) in childhood and adolescence is associated with increased substance use. Empirical evidence, using longitudinal epidemiologic data, may provide support for interventions to improve AA as a means to reduce risk of drug abuse (DA). Objective: To clarify the nature of the association between adolescent AA and risk of DA by using instrumental variable and co-r

To assess etiological and clinical consequences of second primary cancers (SPCs) in prostate cancer (PC) patients, we followed newly diagnosed patients to identify men who were diagnosed with a SPC and recorded their causes of death. We used the Swedish Family-Cancer Database to assess relative risks (RRs) and causes of death in SPCs until the year 2015 in patients with a PC diagnosis between 2001

Leptospirosis is a widespread zoonotic and neglected infectious disease of human and veterinary concern that is caused by pathogenic Leptospira species. After entrance in the host, pathogenic leptospires evade the host natural defense mechanisms in order to propagate and disseminate to multiple organs. Myeloperoxidase is an enzyme stored in neutrophils azurophilic granules, and is released upon ne

The rapid growth of cities requires effective management of transport demand and restructuring of transport systems to address the needs of growing urban populations in an environmentally, socially and economically sustainable way. In recent years, car sharing has emerged as an alternative to owning cars in cities, which has potential to bring environmental gains and address social considerations.

This paper aims to contribute to the ongoing conceptual development and practical pursuit of resilience, the ability to absorb and respond to shocks, in an agricultural and climate change context. It builds on work that aims to dissolve the nature-society dualism and naturalisation of power relations inherent in systems thinking by developing and extending a framework originally conceived to integ

BACKGROUND: Berry pomace is a valuable but little used by-product of juice manufacturing. When processed to a stable fruit powder, the composition differs from that of the whole fruit. To facilitate application in foods, a detailed knowledge of its composition and physicochemical properties is essential. RESULTS: Blackcurrant, redcurrant, chokeberry, rowanberry and gooseberry were selected for ana

Denna bok bygger på aktuell forskning om opioidmissbruk i dess olika former och om lösningar för personer som fastnat i ett opioidmissbruk. Utifrån forskningen besvarar vi frågor som: Varför börjar unga människor använda dessa preparat? Varför är det så svårt att sluta när man har blivit beroende av opioider? Hur ser framgångsrik behandling ut?Under de senaste tjugo åren har olika opioidpreparat s

Objectives: Constant infusion lumbar infusion test (LIT) is an important way to find which patients, of those with signs and symptoms corresponding to normal pressure hydrocephalus (NPH) who will improve from shunt operation. LIT is a stress test on the ability for cerebrospinal fluid re-absorbtion. The aim of this study is to show how the information from LIT can be improved by quantitative analy

Perovskite based photovoltaic devices are popularised by the rapid increase in their efficiencies. Understanding the fundamental physics and chemistry processes occurring upon excitation is key. We monitored the temporal evolution of the population and depopulation dynamics of various electronic states in FA0.85MA0.15PbI2.55Br0.45 by means of ultrafast transient absorption spectroscopy in the visi

Children with medulloblastoma (MB) are predisposed for negative cognitive sequela, which has been widely identified in this population. The purpose of the present study was to explore cognitive deficits and psychopathological symptoms and analyse their relation among MB survivors. The Wechsler Intelligence Scale for Children and the Mini International Neuropsychiatric Interview (MINI-KID) was admi

Statistical information such as death risk estimates is frequently used for illustrating the magnitude of a problem. Such mortality statistics are however easier to evaluate if presented next to an earlier estimate, as the two data points together will illustrate an upward or downward change. How are people influenced by such changes? In seven experiments, participants read mortality statistics (e

Based on his study on the American black ghetto and the French working-class banlieues, Loic Wacquant (2007) conceptualises territorial stigmatisation to capture how the negative perception of relegated urban territories affects their inhabitants and the public policies toward them. Most of the subsequent studies on the topic are done in similar Western post-Fordist and post-colonial settings, and

Objectives. An acute coronary occlusion and its possible subsequent complications is one of the most common causes of death. One such complication is ventricular fibrillation (VF) due to myocardial ischemia. The severity of ischemia is related to the amount of coronary arterial collateral flow. In dog studies collateral flow has also been shown to be associated with QRS prolongation. The aim of th

In cytoplasm, protein γ-tubulin joins with various γ-tubulin complex proteins (GCPs) to form a heterotetramer γ-tubulin small complex (γ-TuSC) that can grow into a ring-shaped structure called the γ-tubulin ring complex (γ-TuRC). Both γ-TuSC and γ-TuRC are required for microtubule nucleation. Recent knowledge on γ-tubulin with regard to its cellular functions beyond participation in its creation o

The effects of weathering on the in-service moisture behavior of wood have received only limited attention so far, with much focus being on the effect of photodegradation on the hydrophobicity of the wood surface. The objective of the present study was to examine the effect of weathering surfaces on the overall moisture behavior of wood specimens exposed to short-term cyclic spraying, with special

BACKGROUND: It is well known that electrical accidents can cause physical injury. Less well known is that long-term consequences may include emotional and cognitive problems. OBJECTIVE: To explore electricians' experiences and perceptions of work-related electrical accidents, with focus on psychological short- and long-term consequences, including how contacts with health care services and the wor

Background: Prostate-specific antigen (PSA) measurement in midlife predicts long-term prostate cancer (PCa) mortality among white men. Objective: To determine whether baseline PSA level during midlife predicts risk of aggressive PCa in black men. Design, setting, and participants: Nested case-control study among black men in the Southern Community Cohort Study recruited between 2002 and 2009. A pr