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Proton-translocating NAD(P)+ transhydrogenase (NNT) is highly expressed in cardiac tissue, where it physiologically supports mitochondrial NADPH production. However, under certain pathological conditions, NNT may shift toward consuming the mitochondrial NADPH pool. Although NNT has been implicated in redox homeostasis, its contribution to cardiac function during aging remains uncertain. In this st

År 2025 presenterades SOU 2025:2 Några frågor om grundläggande fri- och rättigheter, där en kommitté fick i uppdrag att bland annat utreda om ökade möjligheter bör införas för att begränsa föreningsfriheten i förhållande till kriminella sammanslutningar. Kommittén drog slutsatsen att sådana möjligheter bör införas, och några månader senare presenterades kommittédirektiv 2025:28 Kriminalisering av In 2025, the government presented the report SOU 2025:2, Some Issues Concerning Fundamental Rights and Freedoms, which tasked a committee with, among other matters, examining whether the freedom of association should be restricted in relation to criminal organizations. The committee concluded that such measures should be introduced and a few months later Directive 2025:28, Criminalization of Parti

Av artikel 6 (1) EKMR följer att alla har rätt att få sina tvister prövade av en domstol. Rättigheten grundar sig på en tanke om rättssäkerhet där förutsebarhet av rättsliga beslut är av central betydelse. Rätten till domstolsprövning är inte absolut utan det är möjligt att avstå från denna rättighet förutsatt att vissa krav är uppfyllda. Avståendet måste exempelvis vara frivilligt samt komma tillAccording to article 6 (1) ECHR everyone has a right to get legal disputes determined by a court. This right is grounded in the principle of legal certainty, in which the predictability of legal decisions is of great importance. The right of access to court is not absolute. It is therefore possible to waive this right provided that certain conditions are met. Such a waiver must for example be made

Vid företagsförvärv är det vanligt att avtalssigneringen och tillträdet sker som två separata moment en viss tid från varandra. En viktig anledning till denna uppdelning är att det ofta föreligger lagkrav som måste vara upp-fyllda innan tillträdet, exempelvis att företagsöverlåtelsen ska godkännas av Konkurrensverket eller av bolagsstämman. Detta medför dock risker för köparen. Vem ska bära ansvarIn company acquisitions, it is common for the signing of the agreement and the transfer of ownership to take place as two separate steps at different times. A major reason for this division is that there are often legal require-ments that must be met before the transfer of ownership can occur, such as the transfer having to be approved by the Swedish Competition Authority or by the company general

Allemansrätten är en rättighet med gamla anor som omfattar stor del av Sveriges yta och tillfaller alla som bor i och vistas i Sverige. Rättighetens materiella innehåll kan endast delvis utläsas ur lag och då närmast uteslutande motsatsvis ur lagbestämmelser. Istället har allemansrätten sin lagliga grund i sedvana. Att det inte alltid står klart vilka rättigheter till annans mark allemansrätten geThe common (legal) right of access to private land, "allemansrätten", is an established privilege that concerns most of Sweden’s territory and applies to anyone living in or staying in the country. The material content of the right can only partially be recognized in the legislation and then almost exclusively e contrario. Instead, the common legal right of access to private land is main

Humans are extremely efficient in learning concepts and in forming new concepts. However, some conceptual systems are more efficient than others. One of the central tasks for conceptual engineering is to construct systems that fulfil some criteria of optimality. I argue that the methods of Knowledge Representation and Machine Learning are not sufficient. This chapter instead proposes that conceptu

This paper analyzes Nahdlatul Ulama’s (NU) involvement in Indonesia's 2024 Presidential Election, focusing on the convergence of ideological and pragmatic motives. The study examines how different factions within NU align with various presidential candidates, driven by both the desire to protect Aswaja values and the need to maintain relevance in the political sphere. Using qualitative methods by

The Neotropical butterfly genus Adelpha Hübner exhibits remarkable species diversity and striking convergence in wing colour patterns potentially explained by mimicry, making it an exceptional model for exploring trait evolution and its relationship with speciation. To date, unresolved phylogenetic relationships hinder a comprehensive understanding of the evolutionary biology of the genus. Using a

Marine copepods are the most abundant multicellular zooplankton in the global oceans. They imprint their surrounding waters with a unique bouquet of chemical compounds, including polar lipids such as copepodamides. Prey organisms can detect copepodamides and respond by inducing defensive traits including bioluminescence, toxin production, changes in colony size, and structural modifications. This

The role of long non-coding RNAs (lncRNAs) in early mammalian embryogenesis remains unclear due to the complexity of the regulatory mechanisms involving lncRNAs and the limited availability of embryo samples. Stem cell-based models, such as mouse gastruloids, provide new ways to address these challenges. Here, we investigate the function of ultra-conserved lncRNA T-UCstem1 in mammalian body plan f

Few-shot segmentation (FSS) tackles data scarcity using multiple priors, but its simplicity limits handling base and novel classes with limited data access. Generalized few-shot semantic segmentation (GFSS) enhances model performance for base classes with abundant data, while novel classes have limited data access, improving generalization with scarce data. Building on the design of query-based se

Understanding three Dimensional (3D) fundamental processes is crucial for academic and industrial applications. Nowadays, X-ray time-resolved tomography, or tomoscopy, is a leading technique for in situ and operando 4D (3D+time) characterization. Despite its ability to achieve 1000 tomograms per second at large-scale X-ray facilities, its applicability is limited by the centrifugal forces exerted

We present a genome assembly from a female specimen of Podarcis melisellensis (Dalmatian wall lizard; Chordata; Lepidosauria; Squamata; Lacertidae). The assembly contains two haplotypes with total lengths of 1,574.91 megabases and 1,437.04 megabases. Most of haplotype 1 (94.94%) is scaffolded into 20 chromosomal pseudomolecules, including the W and Z sex chromosomes, while most of haplotype 2 (97.

This introduction to the Special Issue explores the ways in which a gendered analysis illuminates histories of segregation. It argues three key points. First, it is essential to understand segregation from an intersectional perspective, one that fully integrates gender alongside other factors and dynamics in order to fully understand the differences and similarities in segregation between differen

High fidelity Large Eddy Simulations (LES) are performed on a non-premixed hydrogen-air annular rotating detonation combustor. The simulations utilize a 22-step hydrogen-air reaction mechanism and an existing flow solver that is optimized for high-speed reacting flows. The selected combustor, designed by the US Air Force Research Laboratory (AFRL), has been extensively studied experimentally acros

Continuum damage mechanics elaborates the continuum mechanics based modelling and simulation of mechanical degradation effects. The objective of this contribution is to briefly review different aspects of continuum damage mechanics of solid continua with a focus on general modelling concepts and application to isotropic as well as anisotropic damage approaches on the one hand, and to discuss possi

This article analyzes approximately two thousand political motions submitted to the Swedish Parliament between 2010 and 2022, aiming to examine whether and how an increased politicization of religion can be identified and its role in shaping political constructions of national identity. The study reveals that religion has become a more controversial issue in political motions during the examined p

Background: Medial plica is a structure with limited understanding of its pathology, but it may be related to the development of medial knee osteoarthritis (OA). We examined the association between medial plica and medial meniscus extrusion (MME), progression of MME, and the risk of early-stage knee OA development in middle-aged persons. Methods: A total of 340 subjects with tibiofemoral Kellgren–

This paper explores the role of guanxi in facilitating innovation within the Chinese construction sector. Guanxi, denoting the network of trust-based relationships, is deeply rooted in Chinese culture and orchestrates innovation activities. As the construction sector shifts toward bio-based building materials, understanding how guanxi influences innovation activities becomes crucial for the sector

Objective: To describe the frequency and types of incidental findings on prostate MRI in a screening setting. Materials and methods: Prostate MRI reports from 2020 to 2024 for men aged 50–56 years were collected from three regional organised prostate cancer testing (OPT) programmes in Sweden. Incidental findings were categorised as suspicious for extra-prostatic malignancy, otherwise likely clinic