Lens–based massive multiple–input multiple–output (MIMO) systems have considerable potential to reduce signal processing cost at millimeter–wave frequencies. As a result, they are able to lower the effective channel dimension via beam selection, realized with a network of radio–frequency (RF) switches. However, lens arrays suffer from the inherent quantization of the beamspace, as well as errors d

Objective To evaluate the psychometric properties of the Fatigue Severity Scale (FSS), the Fatigue Impact Scale (FIS), and the Multidimensional Fatigue Inventory (MFI-20) in persons with late effects of polio (LEoP). More specifically, we explored the data completeness, scaling assumptions, targeting, reliability, and convergent validity. Methods A postal survey including FSS, FIS, and MFI-20 was

Introduction: Arterial stiffness is recognized as an intermediate phenotype and predictor of cardiovascular disease. Arterial stiffness is complex in origin with contributions from lifestyle and genetic factors. However, the association between single nucleotide polymorphisms (SNPs) and arterial stiffness remains unclear. Objective: The aim is to assess whether a multilocus genetic risk score (GRS

Abrupt climatic changes have occurred several times in the past, leading to large-scale modifications of vegetation patterns with important consequences for the global carbon cycle. Dynamic global vegetation models (DGVM) constitute an advanced tool for reconstructing past or predicting future shifts in vegetation distributions in response to climatic change on a global scale. The Lund-Potsdam-Jen

We present a bottom-up approach to simulate the terrestriál isotopic carbon variations using the Lund-Postsdam-Jena dynamic global vegetation model (LPJ-DGVM). LPJ is extended to include isotopic fractionation of 13C at the leaf level during assimilation and includes a full isotopic terrestrial carbon cycle. The model thus allows a quantitative analysis of the net biosphere exchange of CO2 and 13C

Few could have foreseen the consequences when the British Parliament, in 1807, passed the Slave Trade Act that sought to abolish slave imports into the British Empire. From population decreases in the British Caribbean to increased prices in the Cape Colony, historical evidence suggests that the effects of the Act were felt far and wide even though commercialization of slaves was still possible wi

Severe lung inflammation and alveolar hemorrhage can be life-threatening in systemic lupus erythematosus (SLE) patients if not treated early and aggressively. Neutrophil influx is the driver key of this pathology, but little is known regarding the molecular events regulating this recruitment. Here, we uncover a role for IL-16/mir-125a in this pathology and show not only that IL-16 is a target for

Overexpression of recombinant proteins in bacteria may lead to their aggregation and deposition in inclusion bodies. Since the conformational properties of proteins in inclusion bodies exhibit many of the characteristics typical of amyloid fibrils. Based on these findings, we hypothesize that the rate at which proteins form amyloid fibrils may be predicted from their propensity to form inclusion b

Mouth ulcers are the most common ulcerative condition and encompass several clinical diagnoses, including recurrent aphthous stomatitis (RAS). Despite previous evidence for heritability, it is not clear which specific genetic loci are implicated in RAS. In this genome-wide association study (n = 461,106) heritability is estimated at 8.2% (95% CI: 6.4%, 9.9%). This study finds 97 variants which alt

Background: Intracerebral hemorrhage (ICH) is the most serious adverse effect of treatment with oral anticoagulants. Prognostic data after ICH associated with non-vitamin K antagonist oral anticoagulants (NOAC) compared to vitamin K antagonists (VKA) are sparse. We compared 90-day survival and functional outcome following NOAC-ICH versus VKA-ICH using data from the Swedish Stroke Register (Riksstr

In this paper we present an approach to gaining increased anonymity from authorities within a VANET. Standardization organizations and researchers working on VANETs recognize privacy as highly important. However, most research focuses on privacy from other vehicles and external attackers, as opposed to privacy from system-administrating authorities. Our proposed solution forces authorities to reso

CONCLUSIONS: The blood group antigen Vel has been one of immunohematology's greatest enigmas: the variation in antigen strength from one individual to another, the property of anti-Vel to readily hemolyze Vel+ red blood cells (RBCs), and the difficulty to screen for sufficient numbers of Vel- blood donors had made Vel a tough nut to crack. In 2013, a small, previously unknown protein called small

This chapter discusses the history of paleopathology in Sweden. Paleopathology of skeletal remains in Sweden is considered a subfield of historical osteology, a discipline that combines the study of human and animal bones from archaeological sites, with roots in the works of Nils-Gustaf Gejvall (1911–1991). The chapter describes the development of the field from its beginnings in paleopathological