Death Wish
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Filmrecension.
Urological problems can be caused by diseases that affect the bladder wall and its innervation. Contraction and relaxation of smooth muscle cells (SMCs) is essential for maintaining detrusor function and for emptying the bladder. It is well established that a family of regulatory proteins called Myocardin Related Transcription Factors (MRTFs) controls the property of SMCs. SMCs have a number of un
Pathogens causing pneumonia utilize the complement regulator vitronectin to evade complement-mediated killing. Although vitronectin is associated with several chronic lung diseases, the role of bronchoalveolar vitronectin in pneumonia has not been studied. This study sought to reveal the involvement of vitronectin in the bronchoalveolar space during pneumonia, to assess the effect of outer membran
Introduction: A previous genome-wide association study found three genetic loci, rs9388451, rs10428132, and rs11708996, to increase the risk of Brugada Syndrome (BrS). Since the effect of these loci in the general population is unknown, we aimed to investigate the effect on electrocardiogram (ECG) parameters and outcomes in the general population. Materials and Methods: A cohort of 6,161 individua
Plastic is a versatile material that has contributed to numerous product innovations and convenience in everyday life. However, plastic production is growing at an alarming rate, and so has the generation of plastic waste. Unsound waste management results in plastic leakage to the environment with multiple adverse effects to ecosystems. Incineration of plastic waste produces excessive greenhouse g
Improving the product lifetime of consumer electronics can provide significant environmental benefits. However, there is a tendency among both professional users and consumers to change products, like computers and mobile phones regularly, and as a result their lifetimes become increasingly shorter. With the rise of the Circular Economy, new policies to promote longer product lifetimes have emerge
Differences in the elemental abundances of planet-hosting stars in binary systems can give important clues and constraints about planet formation and evolution. In this study we performed a high-precision, differential elemental abundance analysis of a wide binary system, HD 80606/80607, based on high-resolution spectra with high signal-to-noise ratio obtained with Keck/HIRES. HD 80606 is known to
A search is conducted for a beyond-the-Standard-Model boson using events where a Higgs boson with mass 125 GeV decays to four leptons (ℓ = e or μ). This decay is presumed to occur via an intermediate state which contains one or two on-shell, promptly decaying bosons: H → ZX/XX → 4ℓ, where X is a new vector boson Zd or pseudoscalar a with mass between 1 and 60 GeV. The search uses pp collision data
An analysis on selecting cutting speed, cutting feed and depth of cut when collecting data for the Colding Tool Life Model based on Woxen's Equivalent Chip Thickness was performed to achieve the lowest possible model error. All possible combinations of a large data set were evaluated with regard to model error. This work shows that an increase of ratio between the highest and lowest cutting speed,
Investigating the chemical homogeneity of stars born from the same molecular cloud at virtually the same time is very important for our understanding of the chemical enrichment of the interstellar medium and with it the chemical evolution of the Galaxy. One major cause of inhomogeneities in the abundances of open clusters is stellar evolution of the cluster members. In this work, we investigate va
This article presents the experimental results of stone wool–layered sandwich constructions, with either steel or gypsum claddings, tested under four different heating exposures: 7 kW/m2 incident radiant heat flux exposure, 60 kW/m2 incident radiant heat flux exposure, parametric time–temperature curve exposure and ISO 834 standard time–temperature exposure. The test apparatus used were a movable
Background: 4D-flow magnetic resonance imaging (MRI) is increasingly used. Purpose: To validate 4D-flow sequences in phantom and in vivo, comparing volume flow and kinetic energy (KE) head-to-head, with and without respiratory gating. Material and Methods: Achieva dStream (Philips Healthcare) and MAGNETOM Aera (Siemens Healthcare) 1.5-T scanners were used. Phantom validation measured pulsatile, th
A popular strategy for meeting over-determination and pre-emption challenges to the comparative counterfactual conception of harm is Derek Parfit’s suggestion, more recently defended by Neil Feit, that a plurality of events harms A if and only if that plurality is the smallest plurality of events such that, if none of them had occurred, A would have been better off. This analysis of ‘harm’ rests o
Objectives: To assess the interreader agreement and reader performance in the evaluation of patients with pancreatic cancer (PC) in two classification systems of local resectability status prior to initiation of therapy, namely the National Comprehensive Cancer Network (NCCN) and Karolinska classification system (KCS). Methods: In this ethics review board-approved retrospective study, six radiolog