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Psychosocial risk factors in families with infants: a municipality survey

Difficulties in a family's psychosocial situation during the period of infancy are associated with mental problems and behavioural disorders in children. The aim of the study was to identify the extent and type of psychosocial factors in families with infants, including social aspects, mental problems and substance abuse as well as circumstances surrounding the birth. All infants born between Marc

The role of poly(ethyleneimine) in stabilization against metal-catalyzed oxidation of proteins: a case study with lactate dehydrogenase.

The protection provided by poly(ethyleneimine) (PEI) to muscle lactate dehydrogenase (LDH) in metal-catalyzed oxidation (MCO) systems (CuSO(4) or FeCl(2) combined with H(2)O(2)) was studied, and comparisons were made with the chelators EDTA and desferal, respectively. The analytical chelating capacity of PEI was estimated to be around 1 mol Cu(2+)/10 mol ethyleneimine for all molecular weights of

The probability of successful IVF outcome after poor ovarian response

Background. To evaluate the relationship between age and poor ovarian response to pregnancy and cancellation rate after IVF stimulation. Methods. Poor ovarian response was defined as 37 years, who were poor responders, had a significantly lower pregnancy rate per OPU (3.0%) compared to normal to high responders in the same age group (22.1%, p < 0.05). Also, 43.6% of women > 37 years, who were cla

Interstitial carbon related defects in low-temperature irradiated Si: FTIR and DLTS studies

The evolution of radiation-induced carbon-related defects in low temperature irradiated oxygen containing silicon has been studied by means of Fourier transform infrared absorption spectroscopy (FTIR) and deep level transient spectroscopy (DLTS). FTIR measurements have shown that annealing of interstitial carbon atom C-i, occurring in the temperature interval 260-300 K, results in a gradual appear

Cryo-TEM studies of DNA and DNA-lipid structures

Studies published between 2001 and 2005 that utilise cryogenic transmission electron microscopy as a tool for investigating solutions containing DNA with or without amphiphiles present are reviewed. DNA or oligonucleotides form complexes with amphiphilic molecules such as lipids, so-called lipoplexes, and the structures and morphologies are excellent objects to study by cryogenic transmission elec

Residual insulin secretion is not coupled to a maintained glucagon response to hypoglycaemia in long-term type 1 diabetes.

OBJECTIVES: To evaluate the influence of residual beta-cell function on glucagon secretion and glucose counter-regulation following hypoglycaemia in type 1 diabetes. DESIGN AND SUBJECTS: The hormonal counter-regulatory responses to standardized insulin-induced hypoglycaemia were investigated, 18 patients with type 1 diabetes of long duration and 12 healthy subjects were investigated. Nine of the d

Monotone operator functions, gaps and power moment problem

The article is devoted to investigation of the classes of functions belonging to the gaps between classes Pn+1 (I) and P, (I) of matrix monotone functions for full matrix algebras of successive dimensions. In this paper we address the problem of characterizing polynomials belonging to the gaps P-n(I) Pn+1 (I) for bounded intervals L We show that solution of this problem is closely linked to soluti

MFA for overdetermined systems reviewed and compared with RNA expression data to elucidate the difference in shikimate yield between carbon- and phosphate-limited continuous cultures of E. coli W3110.shik1

The present contribution focuses on the mathematical techniques used to solve steady state metabolic models for the case of an overdetermined system. Even when parts of the system are underdetermined it is possible to solve the model partially and obtain statistically meaningful results. This is illustrated with data gathered from a set of E. coli W3110.shik1 phosphate- or carbon-limited continuou

Synthesis of chiral, amphiphilic, and water-soluble chiral macrocycles via urea formation.

A simple, efficient, and flexible procedure for the synthesis of chiral, amphiphilic, and water-soluble macrocycles is reported. Acylation of p-xylylenediamine with N-Fmoc-protected glycine, -aspartic acid, -glutamic acid, and -arginine, followed by removal of Fmoc-groups, gave amino acid:p-xylylene conjugate diamines, which were converted to ten macrocycles via stepwise urea formation using p-nit

Geriatrik är ett försummat ämne i svensk läkarutbildning "Äldreparadoxen" kräver rejäl satsning

A survey at all six medical faculties in Sweden in the spring 2004 showed that basic medical schooling (Medical School) only included an average of 59 full hours of geriatrics, with a fivefold variation between universities (19 to 106 hours). This is despite the fact that the need for geriatric skills in the health care sector is steadily increasing. A test of general knowledge in geriatrics just

Methodologies for model calibration to assist the design of a preparative ion-exchange step for antibody purification

This work proposes methodologies using a model-based approach to gain knowledge on and assist the development of an ion-exchange step in a protein purification process; the separation of IgG from a mixture containing IgG, insulin and transferrin. This approach is suitable for capture and intermediate steps in a process. Both methods involve four consecutive steps. Firstly, the retention of the dif

Solute transport dynamics by high-resolution dye tracer experiments - Image analysis and time moments

Accurate measurements of solute concentration are needed to conduct studies of solute transport process in unsaturated soil. In this paper we present a method of obtaining accurate measurements in and space using dye infiltration and image analysis. The soil color was related to the dye concentration in the soil (C-s) using 74 small calibration samples. The overall root mean square error (RMSE) 0.

Different cysteine proteinases involved in bone resorption and osteoclast formation

Cysteine proteinases, especially cathepsin K, play an important role in osteoclastic degradation of bone matrix proteins and the process can, consequently, be significantly inhibited by cysteine proteinase inhibitors. We have recently reported that cystatin C and other cysteine proteinase inhibitors also reduce osteoclast formation. However, it is not known which cysteine proteinase(s) are involve

Southward migration and fuel deposition of Red Knots Calidris canutus

We compared the differences between spring and autumn in migration speed, fuelling rates and fuel loads of migrating Red Knots Calidris canutus. As a basis we used ringing data from Ottenby Bird Observatory, southeastern Sweden, collected 1948–2003, with morphometrical data from 1990–2003. Numbers ringed varied between 0 and 301 per year (average 56). Morphometrics, recoveries and recaptures of ri