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Glucocorticoids, such as dexamethasone and prednisolone, are widely used in cancer treatment. Different hematological malignancies respond differently to this treatment which, as could be expected, correlates with treatment outcome. In this study, we have used a glucocorticoid-induced gene signature to develop a deep learning model that can predict dexamethasone sensitivity. By combining gene expr
Purpose: Although tumor infiltrating lymphocytes (TIL) assessment has been acknowledged to have both prognostic and predictive importance in triple negative breast cancer (TNBC), it is subject to inter and intra-observer variability that has prevented widespread adoption. Here we constructed a machine-learning based breast cancer TIL scoring approach and validated its prognostic potential in multi
Considering that ‘social work with older people’ refers to something that is carried out with older people, it is of crucial importance to reveal the meaning of ‘the social’ from the perspective of the elderly. The aim of this article is to reveal how older people go about achieving meaningful social interactions in everyday life in the context of eldercare services and the role of social work pra
The ability to recognize the emotions of others is a crucial skill. In the visual modality, sensorimotor mechanisms provide an important route for emotion recognition. Perceiving facial expressions often evokes activity in facial muscles and in motor and somatosensory systems, and this activity relates to performance in emotion tasks. It remains unclear whether and how similar mechanisms extend to
Irregular dietary intakes impairs estimations from food records. Biomarkers and method combinations can be used to improve estimates. Our aim was to examine reproducibility from two assessment methods, compare them, and validate intakes against objective biomarkers. We used the Malmö Offspring Study (55% women, 18-71 y) with data from a 4-day food record (4DFR) and a short food frequency questionn
Background: The ZBTB16-RARA fusion gene, resulting from the reciprocal translocation between ZBTB16 on chromosome 11 and RARA genes on chromosome 17 [t(11;17)(q23;q21)], is rarely observed in acute myeloid leukemia (AML), and accounts for about 1% of retinoic acid receptor-α (RARA) rearrangements. AML with this rare translocation shows unusual bone marrow (BM) morphology, with intermediate aspects
Acute myeloid leukemia (AML) is a grave disease with an incidence of 4 per 100,000 a year. It can present in all ages, but the median age is 70 years. One-third of such patients have secondary AML, that is, AML following chemoradiotherapy or a transformation from previous myelodysplastic syndrome (MDS) or myeloproliferative neoplasia. A combination of genetic, epigenetic, and environmental factors
In this paper, a novel membrane reactor (MR) for methanol steam reforming is modeled to produce fuel cell grade hydrogen, which can be used as the inlet fuel for a later developed 500-W horizon polymer electrolyte fuel cell (PEFC) stack. The backpropagation (BP) neural network algorithm is employed to develop the mapping relation model between the MR's prime operational parameters and fuel cell ou
The malaria parasite Plasmodium relictum is one of the most widespread species of avian malaria. As in the case of its human counterparts, bird Plasmodium undergoes a complex life cycle infecting two hosts: the arthropod vector and the vertebrate host. In this study, we examined transcriptomes of P. relictum (SGS1) during crucial timepoints within its vector, Culex pipiens quinquefasciatus. Differ
How we behave in daily life has an impact on environmental emergencies. In the decisions that we take every day, decisions that are important for the climate, the built environment has a vital but not so noticed part. The project Urban design and everyday life choices recognises the built environment as a co-producer of climate ethics. One of the project studies focuses on everyday choices regardiHow we behave in daily life has an impact on environmental emergencies. In the decisions that we take every day, decisions that are important for the climate, the built environment has a vital but not so noticed part. The project Urban design and everyday life choices recognises the built environment as a co-producer of climate ethics. One of the project studies focuses on everyday choices regardi
Natural products, also called secondary metabolites, are small molecules that are not involved in main life processes. These can be produced by any living organism and play important roles as chemical weapons, protecting the organism from the competitive environment.Due to their bioactivity, natural products present in medicinal plants, mushrooms (and other organisms such as bacteria and algae) ha
In addition to the trichilianones A–D recently reported from Trichilia adolfi, a continuing investigation of the chemical constituents of the ethanol extract of the bark of this medicinal plant yielded the five new limonoids 1–5. They are characterized by having four fused rings and are new examples of prieurianin-type limonoids, having a ε-lactone which in 4 and 5 is α, β- unsaturated. The struct
In this chapter we focus on the territorialisation of grocery shoppers and their routes and routines in the city district Western Harbour in Malmö. The Western Harbour is an urban area close to the sea that was built to afford a sustainable and ecologically- friendly way of life. Here we are interested in how the mundane territorialised role of the grocery shopper has evolved among the inhabitantsIn this chapter we focus on the territorialisation of grocery shoppers and their routes and routines in the city district Western Harbour in Malmö. The Western Harbour is an urban area close to the sea that was built to afford a sustainable and ecologically-friendly way of life. Here we are interested in how the mundane territorialised role of the grocery shopper has evolved among the inhabitants
Anmeldelse af: Ditte Darko. Kort og godt om Seksuel chikane & #Metoo. Dansk Psykologisk Forlag, 2021.
En stor majoritet av studenter som har gått humanistiska och teologiska utbildningar får arbete och dessutom har de nytta av utbildningen i privatlivet. Det skriver debattörer bakom en ny rapport från Lunds universitet.
Affiliative behaviors between previous opponents, or between either aggressor or victim and a third-party individual, after an agonistic interaction.
