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High-dose fast infusion of parenteral iron isomaltoside is efficacious in inflammatory bowel disease patients with iron-deficiency anaemia without profound changes in phosphate or fibroblast growth factor 23

Objective: Iron isomaltoside (Monofer®) is a high-dose intravenous iron preparation with good tolerability and efficacy in inflammatory bowel disease (IBD) patients with iron deficiency anaemia (IDA). This trial evaluates the safety and efficacy, including effect on intact fibroblast growth factor 23 (iFGF23) of a high single dose and cumulative doses of iron isomaltoside in IBD patients with IDA.

Hubble Space Telescope observations of the host galaxies and environments of calcium-rich supernovae

Calcium-rich supernovae (SNe) represent a significant challenge for our understanding of the fates of stellar systems. They are less luminous than other SN types and they evolve more rapidly to reveal nebular spectra dominated by strong calcium lines with weak or absent signatures of other intermediate-and iron-group elements, which are seen in other SNe. Strikingly, their explosion sites also mar

Fyra för landet nya skalbaggar funna i Häckeberga, Skåne

Four species of Coleoptera, not previously reported from Sweden are presented; Euconnus campestris (Schaufuss, 1866) (Staphylinidae: Scydmaeninae), Scopaeus ryei Wollaston, 1872 (Staphylinidae: Paederinae), Acritus homoeopaticus Wollaston, 1857 (Histeridae) and Ephistemus reitteri Casey, 1900 (Cryptophagidae). They have all been collected using car net in an area next to the lake Häckeberga in Sca

Orosomucoid, carotid plaque, and incidence of stroke

Background and Purpose - Orosomucoid (α-1-acid glycoprotein) is an acute-phase protein that has been implicated in anti-inflammatory, immunomodulating, and angiogenic pathways. Orosomucoid has also been associated with coronary disease and stroke. The relationship between orosomucoid, carotid plaque, and stroke incidence were explored in this study. Methods - Plasma levels of orosomucoid were asse

Prasugrel 5 mg inhibits platelet P-selectin and GPIIb–IIIa expression in very elderly and non elderly : results from the GENERATIONS trial, a pharmacodynamic study in stable CAD patients

Platelet P-selectin and activated glycoprotein IIb–IIIa (GPIIb–IIIa) are markers of platelet activation and mediates platelet aggregation. Prasugrel (Pras) 5 mg may be used in very elderly (VE) acute coronary syndrome (ACS) patients undergoing PCI, but its effect on platelet P-selectin and activated GPIIb–IIIa in those patients is not known. Stable ACS patients, VE (78 ± 5 years, n = 23) and non-e

“We are not in this to save the polar bears!” : the link between community renewable energy development and ecological citizenship

The transition from a fossil fuel-based energy system to a renewable one has emerged as a priority for many governments. This, in turn, has facilitated a rapid increase in renewable energy investments. However, this development raises important questions about the sustainability of energy governance when it comes to access and control of energy, public participation and transparency. In this artic

Vital capacity and COPD : The Swedish CArdioPulmonary bioImage Study (SCAPIS)

Background: Spirometric diagnosis of chronic obstructive pulmonary disease (COPD) is based on the ratio of forced expiratory volume in 1 second (FEV1)/vital capacity (VC), either as a fixed value 1/VC ratio in a general population setting. The second aim was to evaluate the characteristics of subjects with COPD who obtained a higher SVC than FVC. Methods: Subjects (n=1,050) aged 50-64 years were i

Young people with psychiatric disabilities and their views of day centres

Young people with psychiatric disabilities may require support in structuring their everyday life. To learn more about the relevance of day centres in this respect, this study aimed to examine the experiences of young people with psychiatric disabilities. A particular focus was on the perceptions of meaningful occupation when visiting day centres, their reasons for not choosing this option when gi

Occupations, perceived stress, and stress-related disorders among women and men in the public sector in Sweden

Background: Stress-related disorders are a public health problem and represent a significant burden to individuals and society. It is, therefore, of importance to regard stress in a wider context and identify risk factors not only at work but in all occupations in everyday life, to prevent ill health. Aim/objective: The aim of this study was to examine potential associations between everyday occup

The initial evaluation of an Internet-based support system for audiologists and first-time hearing aid clients

Objectives: Audiologists provide professional contact and support between appointments to clients with hearing impairment using telephone and e-mail, but more advanced and flexible technological platforms are also possible. The present study aimed to evaluate the clinical application of an Internet-based support system for audiologists and their first-time hearing aid clients. Design: An Internet-

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer

Objective Clinical genetic testing is commercially available for rs61764370, an inherited variant residing in a KRAS 3′ UTR microRNA binding site, based on suggested associations with increased ovarian and breast cancer risk as well as with survival time. However, prior studies, emphasizing particular subgroups, were relatively small. Therefore, we comprehensively evaluated ovarian and breast canc

Production of bio-oil from lignin extracted from kraft black liquor by the Sunmembrane process

It is essential for the pulp and paper industry to utilize as much of the forest raw material as possible to achieve the sustainability goals and to increase the profit. The fibres that are liberated during the kraft pulping process are used for pulp production, while the rest of the components from the wood are mainly incinerated. Lignin is one major byproduct from the kraft pulping process. It h

Cellulosic Bioethanol Production

This chapter discusses some aspects of various separation technologies applied in bioethanol production from lignocellulosic materials. Bioethanol can be produced from lignocellulosic biomass using several different process configurations. The main energy-demanding process steps in lignocellulosic ethanol production are distillation to concentrate the ethanol, adsorption to remove the final conten

Validation of the thermophysiological model by Fiala for prediction of local skin temperatures

The most complete and realistic physiological data are derived from direct measurements during human experiments; however, they present some limitations such as ethical concerns, time and cost burden. Thermophysiological models are able to predict human thermal response in a wide range of environmental conditions, but their use is limited due to lack of validation. The aim of this work was to vali

Regional Branching Reconsidered : Emergence of the Fuel Cell Industry in European Regions

The literature on economic geography suffers from a lack of attention to the emergence of new industries. Recent literature on "regional branching" proposes that new industries emerge in regions where preexisting economic activities are technologically related to the emerging industry. This article provides a more grounded basis for the emerging literature on regional branching by confronting the