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Increase in hepatic lipase activity after testosterone substitution in men with hypogonadism of pituitary origin

Ten men with hypogonadism of pituitary origin were studied before and during testosterone substitution therapy with regard to effects on the activities of hepatic lipase (HL) and lipoprotein lipase (LPL) in postheparin plasma, and on plasma lipoprotein concentrations. The mean (+/- SEM) testosterone level increased from 1.8 +/- 0.5 to 16.3 +/- 2.4 nmol/l. The mean activity of HL rose from 327.1 +/

A Framework for Evaluating Enterprise Systems Implementation Methodologies in Action

Enterprise Systems (ES) are often the largest and most important Information Systems (IS) an organisation employs. Most ES are rented or bought as COTS (Commercial Off The Shelf) software. The use of COTS leads to a distinction between the development of the ES software—done by ES software providers, like SAP and Microsoft—and the implementation of ES software in a specific organisation. Implement

A Monte Carlo study of the energy dependence of Al2O3 : C crystals for real-time in vivo dosimetry in mammography

In a previous experimental study, a novel method for in vivo dosimetry has been investigated, based on radioluminescence (RL) and optically stimulated luminescence (OSL). However, because of (fie large difference in atomic composition between the detector material and the breast tissue, relatively large energy dependence in low-energy X-ray beams can be expected. In the present work, the energy de

An experimental and theoretical investigation of the effect of flow maldistribution on the thermal performance of plate heat exchangers

An experimental and theoretical study of the effect of flow maldistribution from port to channel on the thermal performance of single and multipass plate heat exchangers is presented. In general, flow maldistribution brings about an increase in pressure drop and decrease of the thermal performance in heat exchangers. This deterioration is found to depend on flow rate, number of channels, and port

Observation and assignment of the hot band nu(2)+nu(1)(9)-nu(1)(9) in (HCN)(2)

The high-resolution infrared absorption spectrum for (HCN)(2) in the spectral region 3100-3300 cm(-1) is recorded in a static multipass cell at 240 K under equilibrium conditions. The spectrum shows extensive rovibrational structures which are due to the bound C-H stretching vibration band nu(2) of (HCN)(2) and several hot bands associated to nu(2). We manage to assign 63 new rovibrational transit

Dilute-acid hydrolysis for fermentation of the Bolivian straw material Paja Brava

Hydrolysis of the straw material Paja Brava, a sturdy grass characteristic for the high plains of Bolivia, was studied in order to find suitable conditions for hydrolysis of the hemicellulose and cellulose parts. Dried Paja Brava material was pre-steamed, impregnated with dilute sulfuric acid (0.5% or 1.0% by wt), and subsequently hydrolyzed in a reactor at temperatures between 170 and 230 degrees

District Heating Expansion Strategies in Detached House Areas

District heating is well expanded in the residential areas in Sweden, although not in detached house areas, where it is often impaired with problems of low heat density, large heat losses and high construction costs. However, due to the changes on the electricity market, increased environmental concerns and technological improvements, the detached houses’ sector is a potential market for district

Overexpression of glial cell line-derived neurotrophic factor using a lentiviral vector induces time- and dose-dependent downregulation of tyrosine hydroxylase in the intact nigrostriatal dopamine system.

The effects of continuous glial cell line-derived neurotrophic factor (GDNF) overexpression in the intact nigrostriatal dopamine (DA) system was studied using recombinant lentiviral (rLV) vector delivery of GDNF to the striatum or substantia nigra (SN) in the rat. Intrastriatal delivery of rLV-GDNF resulted in significant overexpression of GDNF in the striatum (2-4 ng/mg tissue) and anterograde tr

XPS and UPS characterization of the TiO2/ZnPcGly heterointerface: Aligmment of energy levels

The electronic structure and the highest occupied molecular orbitals (HOMO)/the lowest unoccupied molecular orbitals (LUMO) alignment at the molecular semiconductor heterointerface of nanostructured TiO2/ZnPcGly dye sensitizer were characterized by X-ray and ultraviolet photoemission spectroscopy (XPS and UPS). The HOMO level of the dye ZnPcGly was determined to be located at 1.62 eV below the Fer

Characterization of contractile P2 receptors in human coronary arteries by use of the stable pyrimidines uridine 5'-O-thiodiphosphate and uridine 5'-O-3-thiotriphosphate

The present study was designed to evaluate the relative contribution of the different contractile P2 receptors in endothelium-denuded human coronary arteries by use of extracellular nucleotides, including the stable pyrimidines uridine 5'-O-3-thiotriphosphate (UTPgammaS) and uridine 5'-O-thiodiphosphate (UDPbetaS). The isometric tension of isolated vessel segments was recorded in vitro, and P2 rec

Atmospheric transport of persistent pollutants governs uptake by Holarctic Terrestrial biota

The atmospheric deposition of PCBs, DDT, and lindane, governed uptake in terrestrial biota in the Scandinavian penninsula. Mammalian herbivores and predators as well as predatory insects contained higher levels of pollutants at locations where the fallout load was high than at stations where atmospheric deposition was lower, and the two variables were significantly correlated.

Small-angle X-ray scattering, light scattering, and NMR study of PEO-PPO-PEO triblock copolymer/cationic surfactant complexes in aqueous solution

The formation of triblock copolymer/surfactant complexes upon mixing a nonionic Pluronic polymer (PEO-PPO-PEO) with a cationic surfactant, hexadecyltrimethylammonium chloride (CTAC), has been studied in dilute aqueous solutions using small-angle X-ray scattering, static and dynamic light scattering, and self-diffusion NMR. The studied copolymer (denoted P123, EO20PO68EO20) forms micelles with a ra

Heterogeneity of homologously expressed Hypocrea jecorina (Trichoderma reesei) Cel7B catalytic module.

The catalytic module of Hypocrea jecorina (previously Trichoderma reesei) Cel7B was homologously expressed by transformation of strain QM9414. Post-translational modifications in purified Cel7B preparations were analysed by enzymatic digestions, high performance chromatography, mass spectrometry and site-directed mutagenesis. Of the five potential sites found in the wild-type enzyme, only Asn56 an