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Online Learning and Placement Algorithms for Efficient Delivery of User Generated Contents in Telco-CDNs

User generated content (UGC) makes up a significant portion of Internet traffic. As opposed to other content, UGC has so far been left outside over-the-top providing network operators content distribution networks (telco-CDN) due to the difficulty in determining optimised placement of such content. The side effect of this is that UGC content is not placed close to end users and therefore occupy un

Handledare på dubbla stolar

En studierektor för doktorander bör inte samtidigt vara handledare eller biträdande handledare. Intressekonflikter kan uppstå. En doktorand kan hamna i en onödig och svår valsituation.

Von Willebrand factor alloantibodies in type 3 von Willebrand disease

The development of neutralizing antibodies is a rare complication of von Willebrand disease treatment. In major surgical procedures for severe forms of the disease, the recognition of ineffective therapy and alternative treatment protocols are lifesaving. We report the case of a 6-year-old girl with type 3 von Willebrand disease in whom inhibitors were sought due to ineffective haemostasis togethe

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Genome-wide association studies have identified breast cancer risk variants in over 150 genomic regions, but the mechanisms underlying risk remain largely unknown. These regions were explored by combining association analysis with in silico genomic feature annotations. We defined 205 independent risk-associated signals with the set of credible causal variants in each one. In parallel, we used a Ba

EuRoSDR GeoBIM project a study in Europe on how to use the potentials of BIM and GEO data in practice

In both the Geo and BIM domains, it is widely acknowledged that the integration of geo-data and BIM-data is beneficial and a crucial step in facing the multi-disciplinary challenges of our built environment. The result of this integration - broadly termed as GeoBIM - has a range of potential uses from district study to road safety. However, from the data perspective, this integration raises the qu

Pathogenic implications of distinct patterns of iron and zinc in chronic MS lesions

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) in which oligodendrocytes, the CNS cells that stain most robustly for iron and myelin are the targets of injury. Metals are essential for normal CNS functioning, and metal imbalances have been linked to demyelination and neurodegeneration. Using a multidisciplinary approach involving synchro

Reliability of Speech Variables and Speech-Related Quality Indicators in the Swedish Cleft Lip and Palate Registry

Objective: To assess the reliability of speech variables and speech-related quality indicators in the Swedish quality registry for cleft lip and palate (CLP). Design: Retrospective study. Setting: Primary care university hospitals. Participants: Fifty-two 5-year-old children with unilateral CLP and 41 with bilateral CLP. Main Outcome Measures: Registry data for “percent nonoral errors” and “percei

Lean Startup and the business model : Experimenting for novelty and impact

Lean Startup has been impacting how startups and incumbents innovate their business models. However, academic understanding of Lean Startup and the associated experimentation process is only emerging. Recent academic critique of Lean Startup by Felin and colleagues (in press) highlights the inadequate guidance provided for hypotheses generation; limits of experiential learning from customer feedba

Limiting conditions for a sustained flame over condensed fuels : Analysis by experiments and stagnant layer theory

Ignition and extinction characteristics of a material determine whether a fire will be initiated and grow. In fire safety engineering, where modellers deal with a multitude of materials, simplified thresholds are commonly used to determine when ignition and extinction occur.Such a threshold is the critical mass flux, which describes when sufficient fuel vapour is produced to support sustained flam

Efficacy and safety of dronedarone in patients with a prior ablation for atrial fibrillation/flutter : Insights from the ATHENA study

Background: The role of antiarrhythmic drugs for atrial fibrillation/atrial flutter (AF/AFL) after catheter ablation is not well established. Hypothesis: We hypothesized that changing the myocardial substrate by ablation may alter the responsiveness to dronedarone. Methods: We assessed the efficacy and safety of dronedarone in the treatment of paroxysmal/persistent atrial fibrillation/atrial flutt

Vanskligt och kort : Om våldshändelser bland unga på institution

... en personal ville kasta en burk bearnaisesås i huvudet på mig ...... då kom det skitmånga personal och bara brotta ned oss, alltså fy fan ... ... alltså konflikter kommer vi inte undan, så enkelt är det ...I "Vanskligt och kort" analyserar författaren fem händelser från vardagen på särskilda ungdomshem i Sverige, en välkänd plats för många ungdomar med kriminella erfarenheter och psykosociala

The instrument suite of the European Spallation Source

An overview is provided of the 15 neutron beam instruments making up the initial instrument suite of the European Spallation Source (ESS), and being made available to the neutron user community. The ESS neutron source consists of a high-power accelerator and target station, providing a unique long-pulse time structure of slow neutrons. The design considerations behind the time structure, moderator

Interfacial properties and interaction between beer wort protein fractions and isohumulone

It is well known that both protein and iso-humulone, originating from barley malt and hops respectively, play important roles in beer foam stability. In this study, we hypothesize that the interaction of iso-humulone and different beer proteins will give rise to adsorbed layers with different characteristics at hydrophobic surfaces. The properties of these adsorbed layers are likely to play a cruc