Massive expansion of erythroid progenitor cells is essential for surviving anemic stress. Research towards understanding this critical process, referred to as stress-erythropoiesis, has been hampered due to the lack of specific marker-combinations enabling analysis of the distinct stress-progenitor cells capable of providing radioprotection and enhanced red blood cell production. Here we present a

On June 13, 2013, the U.S. Supreme Court decided the Myriad gene patent case. In a unanimous judgment the Court held that patent claims directed to isolated genomic DNA are identical to the naturally occurring sequence and thus unpatentable “products of nature”. This decision affects all isolated"products of nature", including genes, gene fragments, and other naturally occurring nucleotide sequenc

Evidence-based software engineering (EBSE) aims to improve research utilization in practice. It relies on systematic methods (like systematic literature reviews, systematic mapping studies, and rapid reviews) to identify, appraise, and synthesize existing research findings to answer questions of interest. However, the lack of practitioners' involvement in the design, execution, and reporting of th

Glasfibernät och stål som appliceras i putsen eller fästes mekaniskt direkt mot väggytan möjliggör en minskning av den bärande väggens tjocklek i murade ytterväggar. Det insparade utrymmet kan användas till mer isolering och därmed bygga mer energieffektiva murade ytterväggar utan att öka den totala väggtjockleken. Väggarnas klimatavtryck minskar.

In recent years radical right parties have gained electoral strength across Europe,while the vote share of social democratic parties has declined. Using regional data and two fixed effect models this study investigates the impact of manufacturing employment and a range of other economic and demographic variables on the vote share of these parties in both national and European parliament elections

The revocation of Broad Institute’s patent EP2771468, marks the latest major development in a series of patent battles over the revolutionary and highly lucrative CRISPR- Cas 9 technology (and other gene editing technologies) in the US and Europe. While this is the first EPO decision in an opposition procedure concerning the Broad patent portfolio, the outcome may have implications for other relat

Artikel om den amerikanska historiens betydelse som politisk kraft.

The article is a comparative inquiry into the roles of Ilia Chavchavadze (1837-1907) and Taras Shevchenko (1818-1861) as national poets and anti-tsarist intellectuals within the context of their respective national traditions (in Georgia and Ukraine). During the period of their activity (19th and the beginning of 20th century), both Ukraine and Georgia were under tsarist imperial rule (albeit the

We present CNFgen, a generator of combinatorial benchmarks in DIMACS and OPB format. The proof complexity literature is a rich source not only of hard instances but also of instances that are theoretically easy but “extremal” in different ways, and therefore of potential interest in the context of SAT solving. Since most of these formulas appear not to be very well known in the SAT community, howe

Background: High-throughput sequencing often provides a foundation for experimental analyses in the life sciences. For many such methods, an intermediate layer of bioinformatics data analysis is the genomic signal track constructed by short read mapping to a particular genome assembly. There are many software tools to visualize genomic tracks in a web browser or with a stand-alone graphical user i

Dynamic resource management is a difficult problem in modern microservice applications. Many proposed methods rely on the availability of an analytical performance model, often based on queueing theory. Such models can always be hand-crafted, but this takes time and requires expert knowledge. Various methods have been proposed that can automatically extract models from logs or tracing data. Howeve

The clear cell, chromophobe and papillary carcinoma as well as oncocytoma are the most common renal tumours. While cases of hybrid renal tumours are well known, the true collision renal tumour of oncocytoma and Papillary Renal Cell Carcinoma (PRCC) is still rare. Herein, we present a case of a true collision renal tumour of an oncocytoma and a PRCC as well as a review of the literature.

Mjölkpulvrets historia. Tycker du att det låter torrt? Då känner du nog inte till att historien om det till synes menlösa mjölkpulvret kantas av allt från giftmord till miljonbedrägerier, nazistanklagelser – och världens allra första brevbomb.I Pulverpionjärerna presenterar livsmedelsteknikern Andreas Håkansson den oväntat rafflande berättelsen om mjölkpulvrets teknik- och kulturhistoria, från des