Global gene expression profiles, consisting mainly of genes associated with proliferation, have been shown to subdivide histological grade 2 breast cancers into groups with different prognosis. We raised the question whether this subdivision could be done using a single proliferation marker, cyclin A. Furthermore, we combined cyclin A (CA), histological grade (G), and estrogen receptor-ER (E) into

Objectives To describe the clinical and ultrasound features of fibroma and fibrothecoma of the ovary. Methods Sixty-eight women with a histological diagnosis of fibroma or fibrothecoma of the ovary who had undergone a preoperative ultrasound examination between 1999 and 2007 were identified from the databases of four ultrasound centers. The tumors were characterized on the basis of ultrasound imag

The PHENIX experiment at RHIC has measured the centrality dependence of the direct photon yield from Au + Au collisions at root s(NN) = 200 GeV down to pT = 0.4 GeV/c. Photons are detected via photon conversions to e(+)e(-) pairs and an improved technique is applied that minimizes the systematic uncertainties that usually limit direct photon measurements, in particular at low pT. We find an excess

Background: In the course of the last four decades, the profession of physiotherapy has progressively expanded its scope of responsibility and its focus on professional autonomy and evidence-based clinical practice. To preserve professional autonomy, it is crucial for the physiotherapy profession to meet society's expectations and demands of professional competence as well as ethical competence. S

Caspase 8 initiates apoptosis downstream of TNF death receptors by undergoing autocleavage and processing the executioner caspase 3 (ref. 1). However, the dominant function of caspase 8 is to transmit a pro-survival signal that suppresses programmed necrosis (or necroptosis) mediated by RIPK1 and RIPK3 (refs 2-6) during embryogenesis and haematopoiesis(7-9). Suppression of necrotic cell death by c

There is no unified view as to what partnering relationships are in the construction industry. The purpose of this paper is to examine the literature in order to identify the main assumptions about partnering relationships in construction research and practice. The literature is compared to the Construction Industry Institute's (CII, 1991) frequently cited definition of partnering as a long-term c

Group 1 grass pollen allergens are a major cause of allergic disease. Specific immunotherapy involving controlled administration of allergens can be used as a disease-modifying treatment for such disease. Recombinant allergen variants with reduced IgE binding capacity may be used as component in such vaccines, as they may induce fewer treatment side effects than materials currently in use. A mutat

I den här artikeln argumenteras för att etnologin har viktig forskningsuppgift i att studera Sanningens rörlighet i termer av kulturella processer, närmare bestämt att besvara frågorna hur, var, när, vem och varför. För att föra det ser författaren ett fruktbart analytiskt angreppssätt i att kombinera diskursteoretiska begrepp och sociologiska och hämtar inspiration från såväl Laclau och Mouffe oc

Objective: The aim of this study was to describe and assess changes in participants' experiences of everyday occupations after nature-based vocational rehabilitation (NBVR), to assess changes regarding symptoms of severe stress and the rate of return to work and possible association with experiencing the occupational value of everyday occupations. Methods: The NBVR was carried out by a transdiscip

A search is made for massive highly ionising particles with lifetimes in excess of 100 ns, with the ATLAS experiment at the Large Hadron Collider, using 3.1 pb(-1) of pp collision data taken at root s = 7 TeV. The signature of energy loss in the ATLAS inner detector and electromagnetic calorimeter is used. No such particles are found and limits on the production cross section for electric charges

Autoimmune diseases are diseases where the immune system attacks the body itself. They are commonly complex diseases with no clear aetiology, a fact that complicates treatment and the study of these diseases. This thesis focuses on the rare group of autoimmune diseases ANCA associated vasculitides (AAV) that are characterized by the presence of anti-neutrophil cytoplasmic antibodies (ANCA) direct

Fires outside school buildings caused by arson are a major problem in Sweden. The initial fire source can involve rubbish or other types of combustibles that can be found at or sometimes brought to the school. As the external fire develops the flames will extend along the façade. If the building is a one-story building, which is a common construction in Swedish school buildings, the fire can sprea

Gamma rays de-exciting isomeric states in the neutron-rich nucleus Os-198(76)122 have been observed following relativistic projectile fragmentation of a 1 GeV per nucleon Pb-208 beam. The ground-state band has properties compatible with oblate deformation. The evolution of the structure of Os isotopes characterized by sudden prolate-oblate shape change is discussed and contrasted with the smooth c

Chip area parameters, such as undeformed chip thickness, equivalent chip thickness, contact edge length, etc., along with tool angles are among defining for the mechanical and thermal conditions of the cutting process. This paper considers the case of external turning with a round insert under variation, in wide range, of back and side rake angles and their influence on the main chip area and surf

The welfare and migration regime of Sweden are undergoing substantial changes, as neo-liberal restructuring is rapidly increasing inequalities, and multicultural policies are in retreat as neo-assimilationist policies are growing. In 2014, the Sweden Democrats, a party conceptualised as culturally racist, was re-elected with 13% of the votes, with a presence in almost all municipalities. While sch

Chronic obstructive pulmonary disease (COPD) independently associates with an increased risk of coronary artery disease (CAD), but it has not been fully investigated whether this co-morbidity involves shared pathophysiological mechanisms. To identify potential common pathways across the two diseases, we tested all recently published single nucleotide polymorphisms (SNPs) associated with human lung