Introduction: Ovarian cancer is a lethal disease with low survival rates for women diagnosed in advanced stages. Current cancer immunotherapies are not efficient in ovarian cancer, and there is therefore a significant need for novel treatment options. The β-galactoside-binding lectin, Galectin-3, is involved in different immune processes and has been associated with poor outcome in various cancer

I september 2022 blev den elev som dödat två lärare på Malmö Latinskola den första 18-åringen att dömas till livstids fängelse. Tova Bennet, juris doktor i straffrätt, menar att målet har flera aspekter som kan motivera en prövning i högsta instans.

This article critically examines the dual role of the Georgian Orthodox Church (GOC) as both a cultural guardian of national identity and a barrier to covenantal pluralism in Georgia. Drawing on legal-financial and comparative-historical analysis, it demonstrates how the GOC’s institutional dominance perpetuates systemic inequalities, including disproportionate state funding, inequitable property

Adopting technological innovations is crucial for organizations to survive in dynamic and competitive market scenarios. Moreover, it is essential to understand the customer needs and respond accordingly. The present research makes use of Technology-Organization-Environment (TOE) framework for Lean Six Sigma Integrated Industry 4.0 (LSSI) adoption. Scholarly literature shows that adopting LSSI dras

In this thesis, we provide a number of novel algebraic means of certifying stability and performance for linear systems constrained in various ways by cones. The purpose is mainly threefold: to provide mathematical statements with applicative potential, to unify seemingly dissimilar results in the literature and thereby increase understanding, and to advance the state of the art on dynamical syste

Beyond 5G/6G communication systems promise to significantly impact the development of a New Generation of CCAM. Reconfigurable Intelligent Metasurfaces (RIM) are by now established as a key enabling technology for 6G Systems. They have been extensively investigated the last few years, as they possess exotic properties allowing for precise control over any aspect of an impinging wave. As such, they

This paper gives a global solution to an H-infinity control problem for systems with symmetric state matrix and state-dependent input matrix. A simple, closed-form expression for the minimizing controller is obtained. This is in contrast to already established theory in which nonlinear H-infinity problems are solved locally. The result is then illustrated through an example, and the potential for

In this paper, we provide the following simple equivalent condition for a nonsymmetric Algebraic Riccati Equation to admit a stabilizing cone-preserving solution: an associated coefficient matrix must be stable. The result holds under the assumption that said matrix be cross-positive on a proper cone, and it both extends and completes a corresponding sufficient condition for nonnegative matrices i

Secondary ice production (SIP) has been attributed to the generation of most ice particles observed in precipitating clouds with cloud tops warmer than 2368C, from various aircraft- and ground-based field observations across the globe. One of the known SIP mechanisms is fragmentation during collisions among ice particles. It has been studied with our theoretical formulation, which has been applied

Introduction The role of global health and sustainable development in medical education is often debated. However, research regarding medical doctors' views on the application of their global health knowledge in the clinical setting remains scarce. This study aimed to explore junior doctors' perceptions of global health and sustainable development, the education they have received on these issues

Det finns kunskap om hur barn rekryteras till brottslighet och vilka åtgärder som kan bryta utvecklingen – och det är inte skärpta straff, skriver Tova Bennet och Sigrid Nikka, forskare i straffrätt vid Lunds universitet.

”All min strävan under denna skoldag – som ett jordeliv utgör – har varit att så mycket som möjligt främja det mänskliga broderskapets förverkligande på vår lilla jord.”Med dessa ord sammanfattade Nelly Thüring (1875–1972) sin livsfilosofi när hon vid 94 års ålder blev intervjuad av Socialdemokratiska kvinnoförbundets tidskrift Morgonbris. Som resetalare hade hon varit med och byggt upp det nystar”All I have strived for during this school day – that an earthly life amounts to – has been to do my utmost to promote the realization of human brotherhood on our little Earth.”This is how Nelly Thüring (1875–1972), at the age of 94, summarized her philosophy of life in an interview with Morgonbris, a journal published by the Swedish Social Democratic Women’s Federation. During the 1920s, she had

Background: In the Sahel, one of the largest semi-arid areas in the world, pastoral livestock is the main source of protein for the local population. The quantification of herbaceous biomass in the Sahelian rangelands is of major importance since it provides food for the livestock. The main method used to monitor the biomass consists of cutting, drying, and weighting it. However, indirect methods

G protein-coupled receptors (GPCRs) are the largest family of cell surface receptors in humans. The binding and dissociation of ligands tunes the inherent conformational flexibility of these important drug targets towards distinct functional states. Here we show how to trigger and resolve protein-ligand interaction dynamics within the human adenosine A2A receptor. For this, we designed seven photo

How do political parties function abroad? How do political parties mobilize overseas supporters during elections? This chapter focuses on the cases of the Justice and Development Party (AKP) and the Peoples’ Democratic Party (HDP), the two most successful Turkish political parties among emigrants. It compares their distinct organisational structures and mobilisation techniques when seeking to reac

IntroductionBeta-lactam antibiotics are essential in the treatment of Gram-negative bloodstream infections. The effect of beta-lactam antibiotics depends on the time of unbound antibiotic concentration above the minimal inhibitory concentration (MIC). An antibiotic concentration above MIC during the whole dosing interval (100% ƒT > MIC) has been suggested as a target for severe infections. The aim