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Vardagliga offentliga rum, torg och platser

Denna text visar att det offentliga rummet fyller många viktiga funktioner, och är en viktig demokratisk fråga. Olika människor har olika stort behov av de resurser som det offentliga rummet har att erbjuda, samtidigt som möjligheten till mobilitet ocksåvarierar. En större ensidighet hos offentliga platser minskar den grad av tillgänglighet som dessa platser kan erbjuda. Om det däremot finns förut

Prognostic and Predictive Factors in Early Alzheimer's Disease : A Systematic Review

Background: Alzheimer's disease (AD) causes progressive decline of cognition and function. There is a lack of systematic literature reviews on prognostic and predictive factors in its early clinical stages (eAD), i.e., mild cognitive impairment due to AD and mild AD dementia. Objective: To identify prognostic factors affecting eAD progression and predictive factors for treatment efficacy and safet

Modelling forests as social-ecological systems : A systematic comparison of agent-based approaches

The multifunctionality of forest systems calls for appropriately complex modelling approaches to capture social and ecosystem dynamics. Using a social-ecological systems framework, we review the functionality of 31 existing agent-based models applied to managed forests. Several applications include advanced cognitive and emotional decision-making, crucial for understanding complex sustainability c

Go out or stress out? Exploring nature connectedness and cumulative stressors as resilience and vulnerability factors in different manifestations of climate anxiety

Given the increasing severity of the climate crisis and, with it, rising climate anxiety, it is imperative to understand what climate anxiety is, how it functions, and how people can cope with it constructively. Nevertheless, research has often mixed different conceptualizations and operationalizations of climate anxiety, yielding sometimes seemingly contradictory findings. This study contributes

Gravitational waves from composite dark sectors

We study under which conditions a first-order phase transition in a composite dark sector can yield an observable stochastic gravitational-wave signal. To this end, we employ the Linear-Sigma model featuring Nf = 3, 4, 5 flavours and perform a Cornwall-Jackiw-Tomboulis computation also accounting for the effects of the Polyakov loop. The model allows us to investigate the chiral phase transition i

Human Leukocyte Antigen Signatures as Pathophysiological Discriminants of Microscopic Colitis Subtypes

Background and Aims: Microscopic colitis [MC] is currently regarded as an inflammatory bowel disease that manifests as two subtypes: collagenous colitis [CC] and lymphocytic colitis [LC]. Whether these represent a clinical continuum or distinct entities is, however, an open question. Genetic investigations may contribute important insight into their respective pathophysiologies. Methods: We conduc

Predicting intensive care need in women with preeclampsia using machine learning–a pilot study

Background: Predicting severe preeclampsia with need for intensive care is challenging. To better predict high-risk pregnancies to prevent adverse outcomes such as eclampsia is still an unmet need worldwide. In this study we aimed to develop a prediction model for severe outcomes using routine biomarkers and clinical characteristics. Methods: We used machine learning models based on data from an i

“What about me?” : lived experiences of siblings living with a brother or sister with a life-threatening or life-limiting condition

Background: There is a lack of knowledge regarding siblings’ experiences of being a brother or sister of a child with a life-threatening or life-limiting condition. Siblings’ perspectives are often expressed through their parents and not by siblings themselves. Method: This study has a qualitative design within hermeneutic phenomenology. Thirteen siblings (ages 3–29) of children with cancer or gen

Single Junction and Tandem Junction Nanowire Solar Cells

Solar cells based on silicon are successfully harvesting solar energy in established and increasingly widespread solar panels. However, their efficiency is limited by the Shockley–Queisser limit. For certain applications where high efficiency is the key figure of merit, the use of multi-junction solar cells is desirable.III–V multi-junction solar cells exhibit the highest efficiencies achieved to

Polymorphisms in Intron 1 of HLA-DRA Differentially Associate with Type 1 Diabetes and Celiac Disease and Implicate Involvement of Complement System Genes C4A and C4B

Polymorphisms in genes in the human leukocyte antigen (HLA) class II region comprise the most important inherited risk factors for many autoimmune diseases including type 1 diabetes (T1D) and celiac disease (CD): both diseases are positively associated with the HLA- DR3 haplotype (DRB1*03:01-DQA1*05:01-DQB1*02:01). Studies of two different populations have recently documented that T1D susceptibili

Structural determination of novel ligands in complex with galectin-8N and galectin-3C, and the discovery of new leads through fragment screening

This thesis aimed to explore the binding pocket of galectin-8N and galectin-3C. Both structure-based drug design and fragment-based drug discovery were utilized in this project, exemplifying the benefits of the different approaches. Structural determination of the proteins in complex with both high affinity ligands, and small fragments was achieved through x-ray crystallography. The structures of

Direct Visualization of Confinement and Many-Body Correlation Effects in 2D Spectroscopy of Quantum Dots

The size tunable color of colloidal semiconductor quantum dots (QDs) is probably the most elegant illustration of the quantum confinement effect. As explained by the simple “particle-in-a-box” model, the transition energies between the levels increase when the “box” becomes smaller. To investigate quantum confinement effects, typically a well-defined narrow size distribution of the nanoparticles i

Unpacking Trust in International Intelligence Cooperation

In recent years, trust has emerged as a topic of interest for scholars aiming to understand the mechanisms enabling transnational intelligence cooperation and focusing on relations of trust between intelligence agencies. The potential dynamics between the trust facilitating transnational intelligence cooperation and the public trust in intelligence agencies on a national level however remains unex

On approximating dependence function and its derivatives

Bivariate extreme value distributions can be used to model dependence of observations from random variables in extreme levels. There is no finite dimensional parametric family for these distributions, but they can be characterized by a certain one-dimensional function which is known as Pickands dependence function. In many applications the general approach is to estimate the dependence function wi

Toxicity of particles derived from combustion of Ethiopian traditional biomass fuels in human bronchial and macrophage-like cells

The combustion of traditional fuels in low-income countries, including those in sub-Saharan Africa, leads to extensive indoor particle exposure. Yet, the related health consequences in this context are understudied. This study aimed to evaluate the in vitro toxicity of combustion-derived particles relevant for Sub-Saharan household environments. Particles (< 2.5 µm) were collected using a high-vol

The bilingual character and liturgical function of "Hermeneia" in Johannine Papyrus manuscripts : A new proposal

In contrast to previous studies, this article argues that the use of ε{hooktop}ρμηνεîαi{dotless} in a group of Johannine papyrus manuscripts is fundamentally characterized by their occurrence in bilingual manuscripts or manuscripts influenced by a bilingual social setting (Greek-Coptic or Greek-Latin). Rather than seeing them as some sort of biblical commentary or oracular statements used for divi

The sulphur threat to marine archaeological artefacts : acid and iron removal from the Vasa

An outbreak of acidity and sulphate salts was observed on the hull of the 17th-century Swedish warship Vasa, following humidity variations in the Vasa Museum during the rainy summer in 2000. Analyses of total sulphur in oak cores sampled from 16 locations showed, in the outermost 2 cm., mean concentrations betwen 0.2 and 6 mass percent. Synchrotron-based sulphur K-edge X-ray absorption spectroscop

Kvinnors och mäns bonusförföräldraskap

Ett ökande omsorgsgivande från förföräldrar till barnbarn är en signifikant utveckling i Sverige (Bordone et al, 2023; Cantillon et al., 2021) en annan utveckling är att allt fler äldre har bonusbarnbarn, till följd av att de eller deras barn lever i ombildade familjer (Bildtgård & Öberg, 2017). Det intensiva förföräldraskapet utmärks av att bio-förföräldrar idag gör, och förväntas göra, mer o